Genome-wide in vivo screen identifies host molecule in promoting cancer metastasis

Yan Gu , Yanfang Liu , Xuetao Cao

Protein Cell ›› 2017, Vol. 8 ›› Issue (6) : 398 -400.

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Protein Cell ›› 2017, Vol. 8 ›› Issue (6) : 398 -400. DOI: 10.1007/s13238-017-0391-9
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Genome-wide in vivo screen identifies host molecule in promoting cancer metastasis

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Yan Gu, Yanfang Liu, Xuetao Cao. Genome-wide in vivo screen identifies host molecule in promoting cancer metastasis. Protein Cell, 2017, 8(6): 398-400 DOI:10.1007/s13238-017-0391-9

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References

[1]

ChenF, QiX, QianM, DaiY, SunY (2014) Tackling the tumor microenvironment: what challenge does it pose to anticancer therapies?Protein Cell5:816–826

[2]

JoyceJA, FearonDT (2015) T cell exclusion, immune privilege, and the tumor microenvironment.Science348:74–80

[3]

LiuY, CaoX (2016) Characteristics and significance of the premetastatic niche.Cancer Cell30:668–681

[4]

LiuY, GuY, HanY, ZhangQ, JiangZ, ZhangX, HuangB, XuX, ZhengJ, CaoX (2016) Tumor exosomal RNAs promote lung premetastatic niche formation by activating alveolar epithelial TLR3 to recruit neutrophils.Cancer Cell30:243–256

[5]

MatloubianM, LoCG, CinamonG, LesneskiMJ, XuY, BrinkmannV, AllendeML, ProiaRL, CysterJG (2004) Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1.Nature427:355–360

[6]

PardollDM (2012) The blockade of immune checkpoints in cancer immunotherapy.Nat Rev Cancer12:252–264

[7]

QuailDF, JoyceJA (2013) Microenvironmental regulation of tumor progression and metastasis.Nat Med19:1423–1437

[8]

TanS, ChenD, LiuK, HeM, SongH, ShiY, LiuJ, ZhangCW, QiJ, YanJ (2016) Crystal clear: visualizing the intervention mechanism of the PD-1/PD-L1 interaction by two cancer therapeutic monoclonal antibodies.Protein Cell7:866–877

[9]

vander Weyden L, ArendsMJ, CampbellAD, BaldT, Wardle-JonesH, GriggsN, Velasco-HerreraMD, TutingT, SansomOJ, KarpNA (2017) Genome-wide in vivo screen identifies novel host regulators of metastatic colonization.Nature541:233–236

[10]

WhiteJK, GerdinAK, KarpNA, RyderE, BuljanM, BussellJN, SalisburyJ, ClareS, InghamNJ, PodriniC (2013) Genomewide generation and systematic phenotyping of knockout mice reveals new roles for many genes.Cell154:452–464

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The Author(s) 2017. This article is published with open access at Springerlink.com and journal.hep.com.cn

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