Synaptonemal complex protein 2 (SYCP2) mediates the association of the centromere with the synaptonemal complex

Jianrong Feng, Shijuan Fu, Xuan Cao, Hao Wu, Jing Lu, Ming Zeng, Lin Liu, Xue Yang, Yuequan Shen

PDF(1653 KB)
PDF(1653 KB)
Protein Cell ›› 2017, Vol. 8 ›› Issue (7) : 538-543. DOI: 10.1007/s13238-016-0354-6
LETTER
LETTER

Synaptonemal complex protein 2 (SYCP2) mediates the association of the centromere with the synaptonemal complex

Author information +
History +

Cite this article

Download citation ▾
Jianrong Feng, Shijuan Fu, Xuan Cao, Hao Wu, Jing Lu, Ming Zeng, Lin Liu, Xue Yang, Yuequan Shen. Synaptonemal complex protein 2 (SYCP2) mediates the association of the centromere with the synaptonemal complex. Protein Cell, 2017, 8(7): 538‒543 https://doi.org/10.1007/s13238-016-0354-6

References

[1]
BisigCG, GuiraldelliMF, KouznetsovaA, ScherthanH, HoogC, DawsonDS, PezzaRJ (2012) Synaptonemal complex components persist at centromeres and are required for homologous centromere pairing in mouse spermatocytes. PLoS Genet8: e1002701
CrossRef Google scholar
[2]
BolorH, MoriT, NishiyamaS, ItoY, HosobaE, InagakiH, KogoH, OhyeT, TsutsumiM, KatoT(2009) Mutations of the SYCP3 gene in women with recurrent pregnancy loss. Am J Hum Genet84:14–20
CrossRef Google scholar
[3]
FrauneJ, SchrammS, AlsheimerM, BenaventeR (2012) The mammalian synaptonemal complex: protein components, assembly and role in meiotic recombination. Exp Cell Res318:1340–1346
CrossRef Google scholar
[4]
HatzopoulosGN, EratMC, CuttsE, RogalaKB, SlaterLM, StansfeldPJ, VakonakisI (2013) Structural analysis of the G-box domain of the microcephaly protein CPAP suggests a role in centriole architecture. Structure21:2069–2077
CrossRef Google scholar
[5]
HosoyaN, OkajimaM, KinomuraA, FujiiY, HiyamaT, SunJ, TashiroS, MiyagawaK (2012) Synaptonemal complex protein SYCP3 impairs mitotic recombination by interfering with BRCA2. EMBO Rep13:44–51
CrossRef Google scholar
[6]
KouznetsovaA, BenaventeR, PastinkA, HoogC (2011) Meiosis in mice without a synaptonemal complex. PLoS ONE6:e28255
CrossRef Google scholar
[7]
LuJ, GuYL, FengJR, ZhouWH, YangX, ShenYQ (2014) Structural insight into the central element assembly of the synaptonemal complex. Sci Rep4:7059
CrossRef Google scholar
[8]
MaH, CookeHJ, ShiQ (2014) Meiosis: recent progress and new opportunities. J Genet Genomics41:83–85
CrossRef Google scholar
[9]
PageSL, HawleyRS (2004) The genetics and molecular biology of the synaptonemal complex. Annu Rev Cell Dev Biol20:525–558
CrossRef Google scholar
[10]
SyrjanenJL, PellegriniL, DaviesOR (2014) A molecular model for the role of SYCP3 in meiotic chromosome organisation. Elife3:02963
CrossRef Google scholar
[11]
VergnolleMAS, TaylorSS (2007) Cenp-F links kinetochores to Ndel1/Nde1/Lis1/Dynein microtubule motor complexes. Curr Biol17:1173–1179
CrossRef Google scholar
[12]
VolkovVA, GrissomPM, ArzhanikVK, ZaytsevAV, RenganathanK, McClure-BegleyT, OldWM, AhnN, McIntoshJR (2015) Centromere protein F includes two sites that couple efficiently to depolymerizing microtubules. J Cell Biol209:813–828
CrossRef Google scholar
[13]
WinkelK, AlsheimerM, OllingerR, BenaventeR (2009) Protein SYCP2 provides a link between transverse filaments and lateral elements of mammalian synaptonemal complexes. Chromosoma118:259–267
CrossRef Google scholar
[14]
YangF, De La FuenteR, LeuNA, BaumannC, McLaughlinKJ, WangPJ (2006) Mouse SYCP2 is required for synaptonemal complex assembly and chromosomal synapsis during male meiosis. J Cell Biol173:497–507
CrossRef Google scholar

RIGHTS & PERMISSIONS

2017 The Author(s) 2017. This article is published with open access at Springerlink.com and journal.hep.com.cn
AI Summary AI Mindmap
PDF(1653 KB)

Accesses

Citations

Detail

Sections
Recommended

/