Crystal structure of HLA-B*5801, a protective HLA allele for HIV-1 infection

References

[1] Adams JJ, Narayanan S, Birnbaum ME, Sidhu SS, Blevins SJ, Gee MH, Sibener LV, Baker BM, Kranz DM, Garcia KC (2016) Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity. Nat Immunol 17:87–94

[2] Buseyne F, Stevanovic S, Rammensee HG, Riviere Y (1997) Characterization of an HIV-1 p24gag epitope recognized by a CD8+ cytotoxic T-cell clone. Immunol Lett 55:145–149

[3] Buseyne F, Chaix ML, Rouzioux C, Blanche S, Riviere Y (2001) Patient-specific cytotoxic T-lymphocyte cross-recognition of naturally occurring variants of a human immunodeficiency virus type 1 (HIV-1) p24gag epitope by HIV-1-infected children. J Virol 75:4941–4946

[4] Chen H, Ndhlovu ZM, Liu D, Porter LC, Fang JW, Darko S, Brockman MA, Miura T, Brumme ZL, Schneidewind A (2012) TCR clonotypes modulate the protective effect of HLA class I molecules in HIV-1 infection. Nat Immunol 13:691–700

[5] Currier JR, Harris ME, Cox JH, McCutchan FE, Birx DL, Maayan S, Ferrari G (2005) Immunodominance and cross-reactivity of B5703-restricted CD8 T lymphocytes from HIV type 1 subtype C-infected Ethiopians. AIDS Res Hum Retroviruses 21:239–245

[6] Deeks SG, Walker BD (2007) Human immunodeficiency virus controllers: mechanisms of durable virus control in the absence of antiretroviral therapy. Immunity 27:406–416

[7] Kloverpris HN, Stryhn A, Harndahl M, Payne R, Towers GJ, Chen F, Riddell L, Walker BD, Ndung’u T, Leslie A (2013) HLAspecific intracellular epitope processing shapes an immunodominance pattern for HLA-B*57 that is distinct from HLA-B*58:01. J Virol 87:10889–10894

[8] Ladell K, Hashimoto M, Iglesias MC, Wilmann PG, McLaren JE, Gras S, Chikata T, Kuse N, Fastenackels S, Gostick E (2013) A molecular basis for the control of preimmune escape variants by HIV-specific CD8+ T cells. Immunity 38:425–436

[9] Navis M, Schellens I, van Baarle D, Borghans J, van Swieten P, Miedema F, Kootstra N, Schuitemaker H (2007) Viral replication capacity as a correlate of HLA B57/B5801-associated nonprogressive HIV-1 infection. J Immunol 179:3133–3143

[10] O’Brien SJ, Gao X, Carrington M (2001) HLA and AIDS: a cautionary tale. Trends Mol Med 7:379–381

[11] Pereyra F, Jia X, McLaren PJ, Telenti A, de Bakker PI, Walker BD, Ripke S, Brumme CJ, Pulit SL, Carrington M (2010) The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. Science 330:1551–1557

[12] Teng MK, Smolyar A, Tse AG, Liu JH, Liu J, Hussey RE, Nathenson SG, Chang HC, Reinherz EL, Wang J-H (1998) Identification of a common docking topology with substantial variation among different TCR-peptide-MHC complexes. Curr Biol 8:409–412

[13] Walker BD, Yu XG (2013) Unravelling the mechanisms of durable control of HIV-1. Nat Rev Immunol 13:487–498

[14] Zhao G, Perilla JR, Yufenyuy EL, Meng X, Chen B, Ning J, Ahn J, Gronenborn AM, Schulten K, Aiken C (2013) Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics. Nature 497:643–646

[15] Zinkernagel RM, Doherty PC(1997) The discovery of MHC restriction. Immunol Today 18:14–17

RIGHTS & PERMISSIONS

2016 The Author(s) 2016. This article is published with open access at Springerlink.com and journal.hep.com.cn