MiRNA-203 suppresses tumor cell proliferation, migration and invasion by targeting Slug in gastric cancer

Liuqing Yang, Hongwei Liang, Yanbo Wang, Shanting Gao, Kai Yin, Zhijian Liu, Xi Zheng, Ying Lv, Lei Wang, Chen-Yu Zhang, Xi Chen, Guifang Xu, Weijie Zhang, Xiaoping Zou

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Protein Cell ›› 2016, Vol. 7 ›› Issue (5) : 383-387. DOI: 10.1007/s13238-016-0259-4
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MiRNA-203 suppresses tumor cell proliferation, migration and invasion by targeting Slug in gastric cancer

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Liuqing Yang, Hongwei Liang, Yanbo Wang, Shanting Gao, Kai Yin, Zhijian Liu, Xi Zheng, Ying Lv, Lei Wang, Chen-Yu Zhang, Xi Chen, Guifang Xu, Weijie Zhang, Xiaoping Zou. MiRNA-203 suppresses tumor cell proliferation, migration and invasion by targeting Slug in gastric cancer. Protein Cell, 2016, 7(5): 383‒387 https://doi.org/10.1007/s13238-016-0259-4

References

[1]
Behnsawy HM, Miyake H, Harada K, Fujisawa M (2013) Expression patterns of epithelial-mesenchymal transition markers in localized prostate cancer: significance in clinicopathological outcomes following radical prostatectomy. BJU Int 111:30–37
CrossRef Google scholar
[2]
John B, Enright AJ, Aravin A, Tuschl T, Sander C, Marks DS (2004) Human MicroRNA targets. PLOS Biol 2:e363
[3]
Krek A, Grun D, Poy MN, Wolf R, Rosenberg L, Epstein EJ, MacMenamin P, Da PI, Gunsalus KC, Stoffel M (2005) Combinatorial microRNA target predictions. Nat Genet 37:495–500
CrossRef Google scholar
[4]
Lewis BP, Shih IH, Jones-Rhoades MW, Bartel DP, Burge CB (2003) Prediction of mammalian microRNA targets. Cell 115:787–798
CrossRef Google scholar
[5]
Markiewicz A, Ahrends T, Welnicka-Jaskiewicz M, Seroczynska B, Skokowski J, Jaskiewicz J, Szade J, Biernat W, Zaczek AJ (2012) Expression of epithelial to mesenchymal transition-related markers in lymph node metastases as a surrogate for primary tumor metastatic potential in breast cancer. J Transl Med 10:226
CrossRef Google scholar
[6]
Phillips S, Kuperwasser C (2014) SLUG: Critical regulator of epithelial cell identity in breast development and cancer. Cell Adhes Migr 8:578–587
CrossRef Google scholar
[7]
Shi Y, Tan YJ, Zeng DZ, Qian F, Yu PW (2015) miR-203 suppression in gastric carcinoma promotes Slug-mediated cancer metastasis. Tumour Biol 8(2):1328–1340
[8]
Smith A, Teknos TN, Pan Q (2013) Epithelial to mesenchymal transition in head and neck squamous cell carcinoma. Oral Oncol 49:287–292
CrossRef Google scholar
[9]
Tanaka Y, Terai Y, Kawaguchi H, Fujiwara S, Yoo S, Tsunetoh S, Takai M, Kanemura M, Tanabe A, Ohmichi M (2013) Prognostic impact of EMT (epithelial-mesenchymal-transition)-related protein expression in endometrial cancer. Cancer Biol Ther 14: 13–19
CrossRef Google scholar
[10]
Zhang K, Chen D, Jiao X, Zhang S, Liu X, Cao J, Wu L, Wang D (2011) Slug enhances invasion ability of pancreatic cancer cells through upregulation of matrix metalloproteinase-9 and actin cytoskeleton remodeling. Lab Invest 91:426–438
CrossRef Google scholar

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2016 The Author(s) 2016. This article is published with open access at Springerlink.com and journal.hep.com.cn
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