Human atlastin GTPases mediate differentiated fusion of endoplasmic reticulum membranes

References

[1] Anwar K, Klemm RW, Condon A, Severin KN, Zhang M, Ghirlando R, Hu J, Rapoport TA, Prinz WA (2012) The dynamin-like GTPase Sey1p mediates homotypic ER fusion in S. cerevisiae. J Cell Biol197: 209-217

[2] Bian X, Klemm RW, Liu TY, Zhang M, Sun S, Sui X, Liu X, Rapoport TA, Hu J (2011) Structures of the atlastin GTPase provide insight into homotypic fusion of endoplasmic reticulum membranes. Proc Natl Acad Sci USA108: 3976-3981

[3] Byrnes LJ, Sondermann H (2011) Structural basis for the nucleotidedependent dimerization of the large G protein atlastin-1/SPG3A. Proc Natl Acad Sci USA108: 2216-2221

[4] Byrnes LJ, Singh A, Szeto K, Benvin NM, O’Donnell JP, Zipfel WR, Sondermann H (2013) Structural basis for conformational switching and GTP loading of the large G protein atlastin. EMBO J32 (3): 369-384

[5] Hoppins S, Lackner L, Nunnari J (2007) The machines that divide and fuse mitochondria. Annu Rev Biochem76: 751-780

[6] Hu J, Shibata Y, Zhu PP, Voss C, Rismanchi N, Prinz WA, Rapoport TA, Blackstone C (2009) A class of dynamin-like GTPases involved in the generation of the tubular ER network. Cell138: 549-561

[7] Ishihara N, Eura Y, Mihara K (2004) Mitofusin 1 and 2 play distinct roles in mitochondrial fusion reactions via GTPase activity. J Cell Sci117: 6535-6546

[8] Kornak U, Mademan I, Schinke M, Voigt M, Krawitz P, Hecht J, Barvencik F, Schinke T, Giesselmann S, Beil FT (2014) Sensory neuropathy with bone destruction due to a mutation in the membrane-shaping atlastin GTPase 3. Brain137: 683-692

[9] Liu TY, Bian X, Sun S, Hu X, Klemm RW, Prinz WA, Rapoport TA, Hu J (2012) Lipid interaction of the C terminus and association of the transmembrane segments facilitate atlastin-mediated homotypic endoplasmic reticulum fusion. Proc Natl Acad Sci109: E2146-E2154

[10] Orso G, Pendin D, Liu S, Tosetto J, Moss TJ, Faust JE, Micaroni M, Egorova A, Martinuzzi A, McNew JA (2009) Homotypic fusion of ER membranes requires the dynamin-like GTPase atlastin. Nature460: 978-983

[11] Rismanchi N, Soderblom C, Stadler J, Zhu PP, Blackstone C (2008) Atlastin GTPases are required for Golgi apparatus and ER morphogenesis. Hum Mol Genet17: 1591-1604

[12] Salinas S, Proukakis C, Crosby A, Warner TT (2008) Hereditary spastic paraplegia: clinical features and pathogenetic mechanisms. Lancet Neurol7: 1127-1138

[13] Wu F, Hu X, Bian X, Liu X, Hu J (2014) Comparison of human and Drosophila atlastin GTPases. Protein Cell press6: 139-146

[14] Zhang M, Hu J (2013) Homotypic fusion of endoplasmic reticulum membranes in plant cells. Front plant sci4: 514

[15] Zhang M, Wu F, Shi J, Zhu Y, Zhu Z, Gong Q, Hu J (2013) ROOT HAIR DEFECTIVE3 family of dynamin-like GTPases mediates homotypic endoplasmic reticulum fusion and is essential for Arabidopsis development. Plant Physiol163: 713-720

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