EF4 knockout E. coli cells exhibit lower levels of cellular biosynthesis under acidic stress

References

[1] Bauerschmitt H, Funes S, Herrmann JM (2008) The membranebound GTPase Guf1 promotes mitochondrial protein synthesis under suboptimal conditions. J Biol Chem 283: 17139-17146

[2] Bijlsma JJE (2000) Identification of loci essential for the growth of helicobacter pylori under acidic conditions. J Infect Dis182: 1566-1569

[3] Bjorkman AJ, Binnie RA, Zhang H, Cole LB, Hermodson MA, Mowbray SL (1994) Probing protein-protein interactions. The ribose-binding protein in bacterial transport and chemotaxis. J Biol Chem269: 30206-30211

[4] Datsenko KA, Wanner BL (2000) One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc Natl Acad Sci USA97: 6640-6645

[5] Karim Z (2010) The importance of the ribosomal elongation factor 4 (LepA). PhD Dissertation, Freie Universität Berlin, Berlin

[6] Keseler IM, Mackie A, Peralta-Gil M, Santos-Zavaleta A, Gama-Castro S, Bonavides-Martinez C, Fulcher C, Huerta AM, Kothari A, Krummenacker M (2013) EcoCyc: fusing model organism databases with systems biology. Nucleic Acids Res41: D605-D612

[7] Kruse T, Bork-Jensen J, Gerdes K (2005) The morphogenetic MreBCD proteins of Escherichia coli form an essential membrane-bound complex. Mol Microbiol55: 78-89

[8] Lane AN, Kirschner K (1991) Mechanism of the physiological reaction catalyzed by tryptophan synthase from Escherichia coli. Biochemistry30: 479-484

[9] Nierhaus KH, Wilson DN (2004) Protein synthesis and ribosome structure: translating the genome (LibreDigital). Wiley, Weinheim

[10] Ote T, Hashimoto M, Ikeuchi Y, Su’etsugu M, Suzuki T, Katayama T, Kato J (2006) Involvement of the Escherichia coli folate-binding protein YgfZ in RNA modification and regulation of chromosomal replication initiation. Mol Microbiol59: 265-275

[11] Pech M, Karim Z, Yamamoto H, Kitakawa M, Qin Y, Nierhaus KH (2011) Elongation factor 4 (EF4/LepA) accelerates protein synthesis at increased Mg2+ concentrations. Proc Natl Acad Sci USA108: 3199-3203

[12] Qin Y, Polacek N, Vesper O, Staub E, Einfeldt E, Wilson DN, Nierhaus KH (2006) The highly conserved LepA is a ribosomal elongation factor that back-translocates the ribosome. Cell127: 721-733

[13] Shoji S, Janssen BD, Hayes CS, Fredrick K (2010) Translation factor LepA contributes to tellurite resistance in Escherichia colibut plays no apparent role in the fidelity of protein synthesis. Biochimie92: 157-163

[14] Zhang X, Newman E (2008) Deficiency in l-serine deaminase results in abnormal growth and cell division of Escherichia coli K-12. Mol Microbiol69: 870-881

RIGHTS & PERMISSIONS

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.