[1] Abdi, K. (2002). IL-12: the role of p40 versus p75.
Scand J Immunol 56, 1-11 .
10.1046/j.1365-3083.2002.01101.x[2] Anderson, P. (2008). Post-transcriptional control of cytokine production.
Nat Immunol 9, 353-359 .
10.1038/ni1584[3] Bandres, E., Cubedo, E., Agirre, X., Malumbres, R., Zarate, R., Ramirez, N., Abajo, A., Navarro, A., Moreno, I., Monzo, M.,
. (2006). Identification by Real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissues. Mol Cancer 5, 29.10.1186/1476-4598-5-29
[4] Bhoj, V.G., and Chen, Z.J. (2009). Ubiquitylation in innate and adaptive immunity. Nature 458, 430-437 .10.1038/nature07959
[5] Denli, A.M., Tops, B.B., Plasterk, R.H., Ketting, R.F., and Hannon, G.J. (2004). Processing of primary microRNAs by the Microprocessor complex. Nature 432, 231-235 .10.1038/nature03049
[6] Garzon, R., Calin, G.A., and Croce, C.M. (2009). MicroRNAs in Cancer. Annu Rev Med 60, 167-179 .10.1146/annurev.med.59.053006.104707
[7] Gatot, J.S., Gioia, R., Chau, T.L., Patrascu, F., Warnier, M., Close, P., Chapelle, J.P., Muraille, E., Brown, K., Siebenlist, U., . (2007). Lipopolysaccharide-mediated interferon regulatory factor activation involves TBK1-IKKepsilon-dependent Lys(63)-linked polyubiquitination and phosphorylation of TANK/I-TRAF. J Biol Chem 282, 31131-31146 .10.1074/jbc.M701690200
[8] Gregory, R.I., Yan, K.P., Amuthan, G., Chendrimada, T., Doratotaj, B., Cooch, N., and Shiekhattar, R. (2004). The Microprocessor complex mediates the genesis of microRNAs. Nature 432, 235-240 .10.1038/nature03120
[9] Guo, H., Ingolia, N.T., Weissman, J.S., and Bartel, D.P. (2010). Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature 466, 835-840 .10.1038/nature09267
[10] Hake, L.E., Mendez, R., and Richter, J.D. (1998). Specificity of RNA binding by CPEB: requirement for RNA recognition motifs and a novel zinc finger. Mol Cell Biol 18, 685-693 .
[11] Henics, T. (1999). Microfilament-dependent modulation of cytoplasmic protein binding to TNFalpha mRNA AU-rich instability element in human lymphoid cells. Cell Biol Int 23, 561-570 .10.1006/cbir.1999.0418
[12] Holm, L., and Rosenstrom, P. (2010). Dali server: conservation mapping in 3D. Nucleic Acids Res 38, W545-549 .10.1093/nar/gkq366
[13] Hudson, B.P., Martinez-Yamout, M.A., Dyson, H.J., and Wright, P.E. (2004). Recognition of the mRNA AU-rich element by the zinc finger domain of TIS11d. Nat Struct Mol Biol 11, 257-264 .10.1038/nsmb738
[14] Hutvagner, G., McLachlan, J., Pasquinelli, A.E., Balint, E., Tuschl, T., and Zamore, P.D. (2001). A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 293, 834-838 .10.1126/science.1062961
[15] Jiang, S., Zhang, L.F., Zhang, H.W., Hu, S., Lu, M.H., Liang, S., Li, B., Li, Y., Li, D., Wang, E.D., . (2012). A novel miR-155/miR-143 cascade controls glycolysis by regulating hexokinase 2 in breast cancer cells. EMBO J 31, 1985-1998 .10.1038/emboj.2012.45
[16] Khader, S.A., Partida-Sanchez, S., Bell, G., Jelley-Gibbs, D.M., Swain, S., Pearl, J.E., Ghilardi, N., Desauvage, F.J., Lund, F.E., and Cooper, A.M. (2006). Interleukin 12p40 is required for dendritic cell migration and T cell priming after Mycobacterium tuberculosis infection. J Exp Med 203, 1805-1815 .10.1084/jem.20052545
[17] Kishimoto, T. (1989). The biology of interleukin-6. Blood 74, 1-10 .
[18] Kishimoto, T. (2005). Interleukin-6: from basic science to medicine--40 years in immunology. Annu Rev Immunol 23, 1-21 .10.1146/annurev.immunol.23.021704.115806
[19] Kolattukudy, P.E., and Niu, J. (2012). Inflammation, endoplasmic reticulum stress, autophagy, and the monocyte chemoattractant protein-1/CCR2 pathway. Circ Res 110, 174-189 .10.1161/CIRCRESAHA.111.243212
[20] Komander, D., Clague, M.J., and Urbe, S. (2009). Breaking the chains: structure and function of the deubiquitinases. Nat Rev Mol Cell Biol 10, 550-563 .10.1038/nrm2731
[21] Kopf, M., Baumann, H., Freer, G., Freudenberg, M., Lamers, M., Kishimoto, T., Zinkernagel, R., Bluethmann, H., and Kohler, G. (1994). Impaired immune and acute-phase responses in interleukin- 6-deficient mice. Nature 368, 339-342 .10.1038/368339a0
[22] Lai, W.S., Kennington, E.A., and Blackshear, P.J. (2002). Interactions of CCCH zinc finger proteins with mRNA: non-binding tristetraprolin mutants exert an inhibitory effect on degradation of AU-rich element-containing mRNAs. J Biol Chem 277, 9606-9613 .10.1074/jbc.M110395200
[23] Lee, Y., Ahn, C., Han, J., Choi, H., Kim, J., Yim, J., Lee, J., Provost, P., Radmark, O., Kim, S., . (2003). The nuclear RNase III Drosha initiates microRNA processing. Nature 425, 415-419 .10.1038/nature01957
[24] Lee, Y., Kim, M., Han, J., Yeom, K.H., Lee, S., Baek, S.H., and Kim, V.N. (2004). MicroRNA genes are transcribed by RNA polymerase II. EMBO J 23, 4051-4060 .10.1038/sj.emboj.7600385
[25] Lee, Y.S., and Dutta, A. (2009). MicroRNAs in cancer. Annu Rev Pathol 4,199-227 .10.1146/annurev.pathol.4.110807.092222
[26] Liang, J., Saad, Y., Lei, T., Wang, J., Qi, D., Yang, Q., Kolattukudy, P.E., and Fu, M. (2010). MCP-induced protein 1 deubiquitinates TRAF proteins and negatively regulates JNK and NF-kappaB signaling. J Exp Med 207, 2959-2973 .10.1084/jem.20092641
[27] Liang, J., Wang, J., Azfer, A., Song, W., Tromp, G., Kolattukudy, P.E., and Fu, M. (2008). A novel CCCH-zinc finger protein family regulates proinflammatory activation of macrophages. J Biol Chem 283, 6337-6346 .10.1074/jbc.M707861200
[28] Liu, Y.C., Penninger, J., and Karin, M. (2005).Immunity by ubiquitylation: a reversible process of modification . Nat Rev Immunol 5, 941-952 .10.1038/nri1731
[29] Matsushita, K., Takeuchi, O., Standley, D.M., Kumagai, Y., Kawagoe, T., Miyake, T., Satoh, T., Kato, H., Tsujimura, T., Nakamura, H., . (2009). Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay. Nature 458, 1185-1190 .10.1038/nature07924
[30] Mizgalska, D., Wegrzyn, P., Murzyn, K., Kasza, A., Koj, A., Jura, J., and Jarzab, B. (2009). Interleukin-1-inducible MCPIP protein has structural and functional properties of RNase and participates in degradation of IL-1beta mRNA. FEBS J 276, 7386-7399 .10.1111/j.1742-4658.2009.07452.x
[31] Naugler, W.E., and Karin, M. (2008). The wolf in sheep's clothing: the role of interleukin-6 in immunity, inflammation and cancer. Trends Mol Med 14, 109-119 .10.1016/j.molmed.2007.12.007
[32] Niu, J., Azfer, A., Zhelyabovska, O., Fatma, S., and Kolattukudy, P.E. (2008). Monocyte chemotactic protein (MCP)-1 promotes angiogenesis via a novel transcription factor, MCP-1-induced protein (MCPIP). J Biol Chem 283, 14542-14551 .10.1074/jbc.M802139200
[33] Niu, J., Wang, K., Graham, S., Azfer, A., and Kolattukudy, P.E. (2011). MCP-1-induced protein attenuates endotoxin-induced myocardial dysfunction by suppressing cardiac NF-small ka, CyrillicB activation via inhibition of Ismall ka, CyrillicB kinase activation. J Mol Cell Cardiol 51, 177-186 .10.1016/j.yjmcc.2011.04.018
[34] O'Connell, R.M., Rao, D.S., and Baltimore, D. (2012). microRNA regulation of inflammatory responses. Annu Rev Immunol 30, 295-312 .10.1146/annurev-immunol-020711-075013
[35] O'Neill, L.A., Sheedy, F.J., and McCoy, C.E. (2011). MicroRNAs: the fine-tuners of Toll-like receptor signalling. Nat Rev Immunol 11, 163-175 .10.1038/nri2957
[36] Paschoud, S., Dogar, A.M., Kuntz, C., Grisoni-Neupert, B., Richman, L., and Kuhn, L.C. (2006). Destabilization of interleukin-6 mRNA requires a putative RNA stem-loop structure, an AU-rich element, and the RNA-binding protein AUF1. Molecular and cellular biology 26, 8228.10.1128/MCB.01155-06
[37] Qi, D., Huang, S., Miao, R., She, Z.G., Quinn, T., Chang, Y., Liu, J., Fan, D., Chen, Y.E., and Fu, M. (2011). Monocyte chemotactic protein-induced protein 1 (MCPIP1) suppresses stress granule formation and determines apoptosis under stress. J Biol Chem 286, 41692-41700 .10.1074/jbc.M111.276006
[38] Rathinam, V.A., Vanaja, S.K., and Fitzgerald, K.A. (2012). Regulation of inflammasome signaling. Nat Immunol 13, 333-332 .10.1038/ni.2237
[39] Reyes-Turcu, F.E., Ventii, K.H., and Wilkinson, K.D. (2009). Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes. Annu Rev Biochem 78, 363-397 .10.1146/annurev.biochem.78.082307.091526
[40] Skalniak, L., Mizgalska, D., Zarebski, A., Wyrzykowska, P., Koj, A., and Jura, J. (2009). Regulatory feedback loop between NF-kappaB and MCP-1-induced protein 1 RNase. FEBS J 276, 5892-5905 .10.1111/j.1742-4658.2009.07273.x
[41] Sun, S.C. (2008). Deubiquitylation and regulation of the immune response. Nat Rev Immunol 8, 501-511 .10.1038/nri2337
[42] Suzuki, H.I., Arase, M., Matsuyama, H., Choi, Y.L., Ueno, T., Mano, H., Sugimoto, K., and Miyazono, K. (2011). MCPIP1 ribonuclease antagonizes dicer and terminates microRNA biogenesis through precursor microRNA degradation. Mol Cell 44, 424-436 .10.1016/j.molcel.2011.09.012
[43] Tanaka, T., Narazaki, M., and Kishimoto, T. (2012). Therapeutic targeting of the interleukin-6 receptor. Annu Rev Pharmacol Toxicol 52, 199-219 .10.1146/annurev-pharmtox-010611-134715
[44] Taylor, G.A., Carballo, E., Lee, D.M., Lai, W.S., Thompson, M.J., Patel, D.D., Schenkman, D.I., Gilkeson, G.S., Broxmeyer, H.E., Haynes, B.F., . (1996). A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency. Immunity 4, 445-454 .10.1016/S1074-7613(00)80411-2
[45] Vinuesa, C.G., Cook, M.C., Angelucci, C., Athanasopoulos, V., Rui, L., Hill, K.M., Yu, D., Domaschenz, H., Whittle, B., Lambe, T., . (2005). A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity. Nature 435, 452-458 .10.1038/nature03555
[46] Volinia, S., Calin, G.A., Liu, C.G., Ambs, S., Cimmino, A., Petrocca, F., Visone, R., Iorio, M., Roldo, C., Ferracin, M., . (2006). A microRNA expression signature of human solid tumors defines cancer gene targets.Proc Natl Acad Sci U S A 103, 2257-2261 .10.1073/pnas.0510565103
[47] Vrotsos, E.G., Kolattukudy, P.E., and Sugaya, K. (2009). MCP-1 involvement in glial differentiation of neuroprogenitor cells through APP signaling. Brain Res Bull 79, 97-103 .10.1016/j.brainresbull.2009.01.004
[48] Xu, J., Peng, W., Sun, Y., Wang, X., Xu, Y., Li, X., Gao, G., and Rao, Z. (2012). Structural study of MCPIP1 N-terminal conserved domain reveals a PIN-like RNase. Nucleic Acids Res . (In Press).10.1093/nar/gks359
[49] Yang, W. (2011). Nucleases: diversity of structure, function and mechanism. Rev Biophys 44, 1-93 .10.1017/S0033583510000181
[50] Younce, C.W., Azfer, A., and Kolattukudy, P.E. (2009). MCP-1 (monocyte chemotactic protein-1)-induced protein, a recently identified zinc finger protein, induces adipogenesis in 3T3-L1 pre-adipocytes without peroxisome proliferator-activated receptor gamma. J Biol Chem 284, 27620-27628 .10.1074/jbc.M109.025320
[51] Younce, C.W., and Kolattukudy, P.E. (2010). MCP-1 causes cardiomyoblast death via autophagy resulting from ER stress caused by oxidative stress generated by inducing a novel zinc-finger protein, MCPIP. Biochem J 426, 43-53 .10.1042/BJ20090976
[52] Yu, D., Tan, A.H., Hu, X., Athanasopoulos, V., Simpson, N., Silva, D.G., Hutloff, A., Giles, K.M., Leedman, P.J., Lam, K.P., . (2007). Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA. Nature 450, 299-303 .10.1038/nature06253
[53] Zhang, Y., Wang, Z., Chen, M., Peng, L., Wang, X., Ma, Q., Ma, F., and Jiang, B. (2012). MicroRNA-143 targets MACC1 to inhibit cell invasion and migration in colorectal cancer. Mol Cancer 11, 23.10.1186/1476-4598-11-23
[54] Zhou, L., Azfer, A., Niu, J., Graham, S., Choudhury, M., Adamski, F.M., Younce, C., Binkley, P.F., and Kolattukudy, P.E. (2006). Monocyte chemoattractant protein-1 induces a novel transcription factor that causes cardiac myocyte apoptosis and ventricular dysfunction. Circ Res 98, 1177-1185 .10.1161/01.RES.0000220106.64661.71
[55] Zielinski, C.E., Mele, F., Aschenbrenner, D., Jarrossay, D., Ronchi, F., Gattorno, M., Monticelli, S., Lanzavecchia, A., and Sallusto, F. (2012). Pathogen-induced human TH17 cells produce IFN-gamma or IL-10 and are regulated by IL-1beta. Nature 484, 514-518 .10.1038/nature10957