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A genome-wide RNAi screen identifies genes regulating the formation of P bodies in
Yinyan Sun1, Peiguo Yang1,2, Yuxia Zhang1, Xin Bao1, Jun Li1, Wenru Hou1, Xiangyu Yao1, Jinghua Han1, Hong Zhang1()
Protein Cell ›› 2011, Vol. 2 ›› Issue (11) : 918-939.
A genome-wide RNAi screen identifies genes regulating the formation of P bodies in
Cytoplasmic processing bodies, termed P bodies, are involved in diverse post-transcriptional processes including mRNA decay, nonsense-mediated RNA decay (NMD), RNAi, miRNA-mediated translational repression and storage of translationally silenced mRNAs. Regulation of the formation of P bodies in the context of multicellular organisms is poorly understood. Here we describe a systematic RNAi screen in
P body /
stress granules /
nonsense-mediated RNA decay (NMD) /
RNA interference /
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