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CSN1 inhibits c-Jun phosphorylation and down-regulates ectopic expression of JNK1
Tomohiko Tsuge1,4(), Suchithra Menon2, Yingchun Tong3, Ning Wei1
Protein Cell ›› 2011, Vol. 2 ›› Issue (5) : 423-432.
CSN1 inhibits c-Jun phosphorylation and down-regulates ectopic expression of JNK1
CSN1 is a component of the COP9 signalosome (CSN), a conserved protein complex with pleiotropic functions in many organs and cell types. CSN regulates ubiquitin-proteasome dependent protein degradation
activator protein 1 (AP-1) / c-Jun phosphorylation / COP9 signalosome (CSN) / CSN1/GPS1 / c-Jun N-terminal kinase 1 (JNK1)
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