Objectives: Lumbar ligamentum flavum cyst is a rare degenerative disease of the spine, which remains poorly reported in the literature. Although full endoscopic surgery has been used for cyst resection, there is no well depicted and accepted technique so far. In this report, we introduce our preliminary experience of the surgical technique for piecemeal cyst resection with a uniaxial large working channel spinal endoscope, and provide the detailed description of endoscopic pathological anatomy.
Methods: This is a retrospective review of a predesigned three-step uniaxial full endoscopic surgical technique. The lumbar ligamentum flavum cysts were removed using a large working channel spinal endoscope. The spinal endoscopic database of the author's department was retrospectively reviewed for patients treated from February 2023 to December 2024. Patients diagnosed as lumbar ligamentum flavum cysts and treated with this technique were included for analysis. The basic information, complications and follow-up clinical outcome parameters (visual analogue scale, VAS, Oswestry Disability Index, ODI, modified MacNab criteria) were collected for evaluation (Shapiro–Wilk test, Wilcoxon's signed-rank test).
Results: Totally, seven patients with ligamentum flavum cyst were included for analysis. All the surgical procedures were successfully performed. The brownish-red soft jelly-like contents and serious adhesion between the ventral wall of the cyst and the dura were notable features of ligamentum flavum cyst. No intraoperative complications were found. The patients were followed up for at least 1 year. The clinical outcomes were satisfactory. Visual analogue scale and Oswestry Disability Index at all follow-up time points were significantly improved (p < 0.05). The excellent and good rate according to modified MacNab criteria was 100% at the last follow-up.
Conclusion: Uniaxial large working channel spinal endoscopy is potentially a safe and effective choice in minimally invasive surgery to remove lumbar ligamentum flavum cyst.
| [1] |
R. H. Moiel, G. Ehni, and M. S. Anderson, “Nodule of the Ligamentum Flavum as a Cause of Nerve Root Compression. Case Report,” Journal of Neurosurgery 27, no. 5 (1967): 456–458.
|
| [2] |
J. Tang, K. Liu, W. Xie, et al., “Endoscopic Treatment of Lumbar Ligamentum Flavum Cyst by Interlaminar Approach: A Minimally Invasive and Effective Alternative to Open Surgery,” Journal of Orthopaedic Surgery and Research 18, no. 1 (2023): 344.
|
| [3] |
V. Singh, T. Rustagi, R. Mahajan, M. Priyadarshini, and K. Das, “Ligamentum Flavum Cyst: Rare Presentation Report and Literature Review,” Neurology India 68, no. 5 (2020): 1207–1210.
|
| [4] |
S. B. Sharma, G. X. Lin, and J. S. Kim, “Full-Endoscopic Resection of Ligamentum Flavum Cyst in Lumbar Spine,” World Neurosurgery 130 (2019): 427–431.
|
| [5] |
H. Taha, Y. Bareksei, W. Albanna, and M. Schirmer, “Ligamentum Flavum Cyst in the Lumbar Spine: A Case Report and Review of the Literature,” Journal of Orthopaedics and Traumatology 11, no. 2 (2010): 117–122.
|
| [6] |
S. Asamoto, H. Jimbo, Y. Fukui, et al., “Cyst of the Ligamentum Flavum—Case Report,” Neurologia Medico-Chirurgica 45, no. 12 (2005): 653–656.
|
| [7] |
E. Cakir, K. Kuzeyli, H. Usul, et al., “Ligamentum Flavum Cyst,” Journal of Clinical Neuroscience 11, no. 1 (2004): 67–69.
|
| [8] |
K. K. V. Kalidindi, M. R. Bhat, M. Gupta, A. Mannem, and H. S. Chhabra, “Ligamentum Flavum Cyst With Acute Onset Motor Deficit: A Literature Review and Case Series,” International Journal of Spine Surgery 14, no. 4 (2020): 544–551.
|
| [9] |
W. M. Nizamani, “Ligamentum Flavum Cyst: An Uncommon but Recognizable and Surgically Correctable Category of Juxtafacet Cyst,” Radiology Case Reports 13, no. 1 (2018): 302–304.
|
| [10] |
D. H. Seo, H. R. Park, J. S. Oh, and J. W. Doh, “Ligamentum Flavum Cyst of Lumbar Spine: A Case Report and Literature Review,” Korean Journal of Spine 11, no. 1 (2014): 18–21.
|
| [11] |
K. Shah, D. Segui, and S. Gonzalez-Arias, “Midline Ligamentum Flavum Cyst of Lumbar Spine,” World Neurosurgery 110 (2018): 284–287.
|
| [12] |
O. Vernet, H. Fankhauser, P. Schnyder, and J. P. Déruaz, “Cyst of the Ligamentum Flavum: Report of Six Cases,” Neurosurgery 29, no. 2 (1991): 277–283.
|
| [13] |
A. P. Chan, T. C. Wong, K. M. Sieh, S. S. Leung, K. Y. Cheung, and K. Y. Fung, “Rare Ligamentum Flavum Cyst Causing Incapacitating Lumbar Spinal Stenosis: Experience With 3 Chinese Patients,” Journal of Orthopaedic Surgery and Research 5 (2010): 81.
|
| [14] |
S. O. Tomasi, G. E. Umana, G. Scalia, et al., “Lumbar Spinous Process-Splitting Technique for Ligamentum Flavum Cyst Removal,” Journal of Neurological Surgery Part A, Central European Neurosurgery 85, no. 2 (2024): 195–201.
|
| [15] |
H. Y. Jung, G. U. Kim, Y. W. Joh, and J. S. Lee, “Ankle and Toe Weakness Caused by Calcified Ligamentum Flavum Cyst: A Case Report,” World Journal of Clinical Cases 11, no. 35 (2023): 8392–8398.
|
| [16] |
L. M. Wildi, M. O. Kurrer, A. Benini, D. Weishaupt, B. A. Michel, and P. Brühlmann, “Pseudocystic Degeneration of the Lumbar Ligamentum Flavum: A Little Known Entity,” Journal of Spinal Disorders & Techniques 17, no. 5 (2004): 395–400.
|
| [17] |
S. DiMaio, E. Marmor, S. Albrecht, and G. Mohr, “Ligamentum Flavum Cysts Causing Incapacitating Lumbar Spinal Stenosis,” Canadian Journal of Neurological Sciences 32, no. 2 (2005): 237–242.
|
| [18] |
J. Haase, “Extradural Cyst of Ligamentum Flavum L 4—A Case,” Acta Orthopaedica Scandinavica 43, no. 1 (1972): 32–38.
|
| [19] |
A. F. Abdullah, R. W. Chambers, and D. P. Daut, “Lumbar Nerve Root Compression by Synovial Cysts of the Ligamentum Flavum. Report of Four Cases,” Journal of Neurosurgery 60, no. 3 (1984): 617–620.
|
| [20] |
J. K. Baker and G. W. Hanson, “Cyst of the Ligamentum Flavum,” Spine 19, no. 9 (1994): 1092–1094.
|
| [21] |
H. Mahallati, C. J. Wallace, K. M. Hunter, J. M. Bilbao, and A. W. Clark, “MR Imaging of a Hemorrhagic and Granulomatous Cyst of the Ligamentum Flavum With Pathologic Correlation,” AJNR. American Journal of Neuroradiology 20, no. 6 (1999): 1166–1168.
|
| [22] |
C. B. Bärlocher and R. W. Seiler, “Vertebral Erosion and a Ligamentum Flavum Cyst. Case Illustration,” Journal of Neurosurgery 93, no. 2 (2000): 335.
|
| [23] |
H. Terada, Y. Yokoyama, N. Kamata, T. Hozumi, and T. Kondo, “Cyst of the Ligamentum Flavum,” Neuroradiology 43, no. 1 (2001): 49–51.
|
| [24] |
R. Gazzeri, A. Canova, C. Fiore, M. Galarza, M. Neroni, and M. Giordano, “Acute Hemorrhagic Cyst of the Ligamentum Flavum,” Journal of Spinal Disorders & Techniques 20, no. 7 (2007): 536–538.
|
| [25] |
G. Ayberk, F. Ozveren, B. Gök, et al., “Lumbar Synovial Cysts: Experience With Nine Cases,” Neurologia Medico-Chirurgica 48, no. 7 (2008): 298–303.
|
| [26] |
M. Miscusi, V. Petrozza, F. M. Polli, S. Forcato, C. D. Rocca, and A. Raco, “Symptomatic Ganglion Cyst of Ligamentum Flavum as a Late Complication of Lumbar Fixation,” Neurologia i Neurochirurgia Polska 46, no. 1 (2012): 82–86.
|
| [27] |
F. Ghent, T. Davidson, and R. J. Mobbs, “Haemorrhagic Lumbar Juxtafacet Cyst With Ligamentum Flavum Involvement,” Case Reports in Orthopedics 2014 (2014): 126067.
|
| [28] |
A. Börekci, P. Kuru Bektaşoğlu, B. Gürer, and E. Çelikoğlu, “Acute Bilateral Foot Drop as Presenting Symptom of Hemorrhagic Synovial Cyst of Lumbar Spine,” World Neurosurgery 108 (2017): 999.
|
| [29] |
S. C. Wang and F. F. Wang, “Lumbar Spinal Canal Stenosis Complicated With Lumbar Ligamentum Flavum Cyst: A Case Report,” Zhongguo Gu Shang 30, no. 5 (2017): 479–480.
|
| [30] |
H. S. Kim, R. Singh, N. M. Adsul, et al., “Symptomatic Tuberculous Ligamentum Flavum Cyst Treated by Full Endoscopic Resection: Review With Technical Notes,” World Neurosurgery 122 (2019): 112–115.
|
| [31] |
K. Watanabe, K. Mitsui, J. Sasaki, and D. Kumaki, “Subacute Hemorrhagic Cyst of the Ligamentum Flavum Occurred in the Lumbosacral Transitional Vertebra Presenting as Progressive Lumbar Nerve Root Compression: A Case Report,” Journal of Spine Surgery 7, no. 2 (2021): 238–243.
|
| [32] |
B. Mohapatra, N. H. Jagadeesh, M. Guha, A. Agarwal, J. George, and T. F. Rehman, “Hemorrhagic Ligamentum Flavum Cyst in the Adjacent Level of Lytic Spondylolisthesis - A Case of Diagnostic and Therapeutic Dilemma,” Journal of Orthopaedic Case Reports 14, no. 4 (2024): 41–46.
|
| [33] |
A. M. Chau, N. R. Pelzer, J. Hampton, et al., “Lateral Extent and Ventral Laminar Attachments of the Lumbar Ligamentum Flavum: Cadaveric Study,” Spine Journal 14, no. 10 (2014): 2467–2471.
|
| [34] |
A. D. Olszewski, M. J. Yaszemski, and A. A. White, “The Anatomy of the Human Lumbar Ligamentum Flavum. New Observations and Their Surgical Importance,” Spine 21, no. 20 (1996): 2307–2312.
|
| [35] |
S. Lawrence, D. Sturgess, and D. Reutens, “The Lumbar Ligamentum Flavum Does Not Have Two Layers and Is Confluent With the Interspinous Ligament,” Clinical Anatomy 33, no. 7 (2020): 978–979.
|
| [36] |
K. A. Gillespie and J. P. Dickey, “Biomechanical Role of Lumbar Spine Ligaments in Flexion and Extension: Determination Using a Parallel Linkage Robot and a Porcine Model,” Spine 29, no. 11 (2004): 1208–1216.
|
| [37] |
A. Merter, M. O. Karaca, and T. Yazar, “Biomechanical Effects of Sequential Resection of the Posterior Ligamentous Complex on Intradiscal Pressure and Resistance to Compression Forces,” Acta Orthopaedica et Traumatologica Turcica 53, no. 6 (2019): 502–506.
|
| [38] |
J. U. Howington, E. S. Connolly, and R. M. Voorhies, “Intraspinal Synovial Cysts: 10-Year Experience at the Ochsner Clinic,” Journal of Neurosurgery 91, no. 2 Suppl (1999): 193–199.
|
| [39] |
B. M. Onofrio and A. D. Mih, “Synovial Cysts of the Spine,” Neurosurgery 22, no. 4 (1988): 642–647.
|
| [40] |
A. G. Brotis, E. Z. Kapsalaki, E. K. Papadopoulos, and K. N. Fountas, “A Cervical Ligamentum Flavum Cyst in an 82-Year-Old Woman Presenting With Spinal Cord Compression: A Case Report and Review of the Literature,” Journal of Medical Case Reports 6 (2012): 92.
|
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2026 The Author(s). Orthopaedic Surgery published by Tianjin Hospital and John Wiley & Sons Australia, Ltd.