Objective: Arthroscopic surgery is recommended for the treatment of hip synovial chondromatosis, as it allows patients to resume daily activities quickly and requires only a short rehabilitation period. Despite its advantages, there is currently no standardized protocol for arthroscopic hip synovectomy, and complete removal of intra-articular loose bodies remains challenging. The objective of this study is to evaluate long-term clinical outcomes of arthroscopic treatment for hip synovial chondromatosis using a standardized protocol based on clock-face-guided, imaging-based lesion localization.
Methods: A consecutive cohort of patients undergoing arthroscopic treatment and diagnosed with synovial chondromatosis between June 2016 and July 2019 was included in the study. All patients underwent preoperative imaging-guided localization of loose bodies followed by arthroscopic removal performed by a single surgeon, with a minimum postoperative follow-up of 30 months. Preoperative and postoperative assessments included standard radiographs (x-ray), three-dimensional computed tomography (3D-CT), magnetic resonance imaging (MRI), intraoperative arthroscopic images, visual analog scale (VAS) for pain, range of motion (ROM), modified Harris Hip Score (mHHS), and International Hip Outcome Tool (iHOT-12). The percentage of patients achieving the minimal clinically important difference (MCID) was calculated to summarize and compare differences in clinical outcomes.
Results: Seventeen patients were enrolled, with a mean postoperative follow-up duration of 71 months. No major complications were observed. Patients achieved weight-bearing ambulation at a mean of 7 days postoperatively and were discharged at a median of 2.5 days (range: 1–3 days). PROs demonstrated significant improvements: VAS for pain decreased from 7.6 to 2.1, mHHS increased from 54.6 preoperatively to 89.4 postoperatively, and iHOT-12 improved from 38.1 to 75.2 (all p < 0.001). At long-term follow-up, all patients met MCID thresholds for both mHHS and iHOT-12 scores.
Conclusion: Arthroscopic treatment using a standardized protocol can result in favorable long-term clinical outcomes.
| [1] |
J. W. Milgram, “Synovial Osteochondromatosis: A Histopathological Study of Thirty Cases,” Journal of Bone and Joint Surgery. American Volume 59 (1977): 792–801.
|
| [2] |
F. Amary, L. Perez-Casanova, H. Ye, et al., “Synovial Chondromatosis and Soft Tissue Chondroma: Extraosseous Cartilaginous Tumor Defined by FN1 Gene Rearrangement,” Modern Pathology 32 (2019): 1762–1771, https://doi.org/10.1038/s41379-019-0315-8.
|
| [3] |
M. D. Murphey, J. A. Vidal, J. C. Fanburg-Smith, and D. A. Gajewski, “Imaging of Synovial Chondromatosis With Radiologic-Pathologic Correlation,” Radiographics 27 (2007): 1465–1488, https://doi.org/10.1148/rg.275075116.
|
| [4] |
Y. Liu, J. Li, N. Ma, et al., “Arthroscopic Treatment of Synovial Chondromatosis of Hip Joint,” Journal of Orthopaedic Surgery and Research 15 (2020): 405, https://doi.org/10.1186/s13018-020-01928-8.
|
| [5] |
R. Zini, U. G. Longo, M. de Benedetto, et al., “Arthroscopic Management of Primary Synovial Chondromatosis of the Hip,” Arthroscopy 29 (2013): 420–426, https://doi.org/10.1016/j.arthro.2012.10.014.
|
| [6] |
J. H. Christensen and J. O. Poulsen, “Synovial Chondromatosis,” Acta Orthopaedica Scandinavica 46 (1975): 919–925, https://doi.org/10.3109/17453677508989279.
|
| [7] |
C. Duif, C. von Schulze Pellengahr, A. Ali, et al., “Primary Synovial Chondromatosis of the Hip – Is Arthroscopy Sufficient? A Review of the Literature and a Case Report,” Technology and Health Care 22 (2014): 667–675, https://doi.org/10.3233/THC-140844.
|
| [8] |
E. Hiza, B. D. Dierckman, C. Guanche, G. Applegate, D. Shah, and J. H. Ryu, “Reliability of the Tonnis Classification and Its Correlation With Magnetic Resonance Imaging and Intraoperative Chondral Damage,” Arthroscopy 35 (2019): 403–408, https://doi.org/10.1016/j.arthro.2018.08.036.
|
| [9] |
J. M. Crotty, J. U. Monu, and T. L. Pope, “Synovial Osteochondromatosis,” Radiologic Clinics of North America 34, no. 2 (1996): 327–342, xi.
|
| [10] |
V. E. Krebs, “The Role of Hip Arthroscopy in the Treatment of Synovial Disorders and Loose Bodies,” Clinical Orthopaedics and Related Research 406 (2003): 48–59, https://doi.org/10.1097/01.blo.0000043043.84315.5e.
|
| [11] |
X. Zhang, G. Gao, J. Wang, and Y. Xu, “Clinical Outcomes After Arthroscopic Treatment of Synovial Chondromatosis in the Hip,” Cartilage 13 (2021): 1324S–1330S, https://doi.org/10.1177/1947603520912316.
|
| [12] |
Y. Zhu, G. Gao, S. Luan, et al., “Longitudinal Assessment of Clinical Outcomes After Arthroscopic Treatment for Hip Synovial Chondromatosis and the Effect of Residual Loose Bodies: Minimum 4-Year and 8-Year Follow-Up,” American Journal of Sports Medicine 52 (2024): 2306–2313, https://doi.org/10.1177/03635465241260354.
|
| [13] |
J. B. Lee, C. Kang, C. H. Lee, P. S. Kim, and D. S. Hwang, “Arthroscopic Treatment of Synovial Chondromatosis of the Hip,” American Journal of Sports Medicine 40 (2012): 1412–1418, https://doi.org/10.1177/0363546512445150.
|
| [14] |
T. Boyer and H. Dorfmann, “Arthroscopy in Primary Synovial Chondromatosis of the Hip: Description and Outcome of Treatment,” Journal of Bone and Joint Surgery. British Volume (London) 90 (2008): 314–318, https://doi.org/10.1302/0301-620X.90B3.19664.
|
| [15] |
F. P. Ferro and M. J. Philippon, “Arthroscopy Provides Symptom Relief and Good Functional Outcomes in Patients With Hip Synovial Chondromatosis,” Journal of Hip Preservation Surgery 2 (2015): 265–271, https://doi.org/10.1093/jhps/hnv044.
|
| [16] |
U. Studler, F. Kalberer, M. Leunig, et al., “MR Arthrography of the Hip: Differentiation Between an Anterior Sublabral Recess as a Normal Variant and a Labral Tear,” Radiology 249 (2008): 947–954, https://doi.org/10.1148/radiol.2492080137.
|
| [17] |
M. Lequesne, J. Malghem, and E. Dion, “The Normal Hip Joint Space: Variations in Width, Shape, and Architecture on 223 Pelvic Radiographs,” Annals of the Rheumatic Diseases 63 (2004): 1145–1151, https://doi.org/10.1136/ard.2003.018424.
|
| [18] |
G. R. Norman, J. A. Sloan, and K. W. Wyrwich, “Interpretation of Changes in Health-Related Quality of Life: The Remarkable Universality of Half a Standard Deviation,” Medical Care 41 (2003): 582–592, https://doi.org/10.1097/01.MLR.0000062554.74615.4C.
|
| [19] |
M. A. Adelani, R. M. Wupperman, and G. E. Holt, “Benign Synovial Disorders,” Journal of the American Academy of Orthopaedic Surgeons 16 (2008): 268–275, https://doi.org/10.5435/00124635-200805000-00005.
|
| [20] |
S. J. Lim, H. W. Chung, Y. L. Choi, Y. W. Moon, J. G. Seo, and Y. S. Park, “Operative Treatment of Primary Synovial Osteochondromatosis of the Hip,” Journal of Bone and Joint Surgery. American Volume 88 (2006): 2456–2464, https://doi.org/10.2106/JBJS.F.00268.
|
| [21] |
A. Marchie, I. Panuncialman, and J. C. McCarthy, “Efficacy of Hip Arthroscopy in the Management of Synovial Chondromatosis,” American Journal of Sports Medicine 39 (2011): 126S–131S, https://doi.org/10.1177/0363546511414014.
|
| [22] |
J. W. Milgram, “The Classification of Loose Bodies in Human Joints,” Clinical Orthopaedics and Related Research 124 (1977): 282–291.
|
| [23] |
J. Morel, R. Audo, M. Hahne, and B. Combe, “Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) Induces Rheumatoid Arthritis Synovial Fibroblast Proliferation Through Mitogen-Activated Protein Kinases and Phosphatidylinositol 3-Kinase/Akt,” Journal of Biological Chemistry 280 (2005): 15709–15718, https://doi.org/10.1074/jbc.M414469200.
|
| [24] |
D. de Sa, N. S. Horner, A. MacDonald, et al., “Arthroscopic Surgery for Synovial Chondromatosis of the Hip: A Systematic Review of Rates and Predisposing Factors for Recurrence,” Arthroscopy 30 (2014): 1499–1504.e2, https://doi.org/10.1016/j.arthro.2014.05.033.
|
| [25] |
M. Abolghasemian, K. Gharanizadeh, P. Kuzyk, Z. Masdari, M. Fakharian, and O. Safir, “Hips With Synovial Chondromatosis May Display the Features of Femoroacetabular Impingement,” Journal of Bone and Joint Surgery. American Volume 96 (2014): e11, https://doi.org/10.2106/JBJS.L.01550.
|
| [26] |
D. Padhy, S. W. Park, W. K. Jeong, D. H. Lee, J. H. Park, and S. B. Han, “Femoroacetabular Impingement due to Synovial Chondromatosis of the Hip Joint,” Orthopedics 32 (2009): 921–923, https://doi.org/10.3928/01477447-20091020-30.
|
| [27] |
A. Startzman, D. Collins, and D. Carreira, “A Systematic Literature Review of Synovial Chondromatosis and Pigmented Villonodular Synovitis of the Hip,” Physician and Sportsmedicine 44 (2016): 425–431, https://doi.org/10.1080/00913847.2016.1216238.
|
| [28] |
R. Ganz, T. J. Gill, E. Gautier, K. Ganz, N. Krügel, and U. Berlemann, “Surgical Dislocation of the Adult Hip: A Technique With Full Access to the Femoral Head and Acetabulum Without the Risk of Avascular Necrosis,” Journal of Bone and Joint Surgery. British Volume (London) 83 (2001): 1119–1124, https://doi.org/10.1302/0301-620x.83b8.11964.
|
| [29] |
N. P. Mahajan, P. K. GS, A. Marfatia, A. V. Mane, A. Gop, and T. C. Patil, “Synovial Chondromatosis of Hip in a Young Patient Salvaged With Mini Arthrotomy Without Hip Dislocation – A Case Report,” Journal of Orthopedic Case Reports 11 (2021): 28–32, https://doi.org/10.13107/jocr.2021.v11.i01.1952.
|
| [30] |
D. A. Doward, M. L. Troxell, and M. Fredericson, “Synovial Chondromatosis in an Elite Cyclist: A Case Report,” Archives of Physical Medicine and Rehabilitation 87 (2006): 860–865, https://doi.org/10.1016/j.apmr.2006.02.030.
|
| [31] |
Y. K. Lee, K. H. Moon, J. W. Kim, J. S. Hwang, Y. C. Ha, and K. H. Koo, “Remaining Loose Bodies After Arthroscopic Surgery Including Extensive Capsulectomy for Synovial Chondromatosis of the Hip,” Clinics in Orthopedic Surgery 10 (2018): 393–397, https://doi.org/10.4055/cios.2018.10.4.393.
|
| [32] |
W. J. Robertson and B. T. Kelly, “The Safe Zone for Hip Arthroscopy: A Cadaveric Assessment of Central, Peripheral, and Lateral Compartment Portal Placement,” Arthroscopy 24 (2008): 1019–1026, https://doi.org/10.1016/j.arthro.2008.05.008.
|
RIGHTS & PERMISSIONS
2026 The Author(s). Orthopaedic Surgery published by Tianjin Hospital and John Wiley & Sons Australia, Ltd.