Correlation Between Functional Scores and Objective Gait Parameters Following Rotating Hinge Knee Megaprosthesis Reconstruction

Meng-Yu Chen , Ming-Yong Gu , Sheng-Rui Chu , Chong Li , Xue-Fei Fu , Kuan Zhang , Ji-Zhou Zeng , Yan-Cheng Liu

Orthopaedic Surgery ›› 2026, Vol. 18 ›› Issue (5) : 1042 -1053.

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Orthopaedic Surgery ›› 2026, Vol. 18 ›› Issue (5) :1042 -1053. DOI: 10.1111/os.70300
RESEARCH ARTICLE
Correlation Between Functional Scores and Objective Gait Parameters Following Rotating Hinge Knee Megaprosthesis Reconstruction
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Abstract

Objective: Although the Musculoskeletal Tumor Society (MSTS) score, Toronto Extremity Salvage Score (TESS), and Knee Society Score (KSS) are widely used for postoperative functional evaluation in patients undergoing rotating hinge knee (RHK) megaprosthesis reconstruction, their accuracy in reflecting objective gait performance remains uncertain. The study aimed to analyze the correlations between these scoring systems and gait parameters.

Methods: This retrospective study included 21 patients who underwent RHK between April 2023 and April 2025. At one-year follow-up, functional outcomes were assessed using MSTS, TESS, and KSS. Gait parameters were collected using the Intelligent Device for Energy Expenditure and Activity (IDEEA v3.1, MiniSun LLC). All functional assessments were completed on the same day as the gait analysis. Linear regression analyzed correlations between each scoring system and gait parameters. Friedman and Wilcoxon signed-rank tests compared median coefficients of determination across scoring systems. Stepwise multiple linear regression was used to examine the relationships between the scoring system subitems and gait parameters.

Results: Significant correlations were observed between all three scoring systems and multiple gait parameters after RHK (p < 0.05). The TESS had a significantly greater median R2 than did the MSTS score and KSS (p < 0.05), especially for walking velocity (R2 = 0.76), step length (R2 = 0.75), initial contact phase (R2 = 0.65), and stride length (R2 = 0.58). Multiple linear regression analysis revealed that the MSTS “walking” and KSS “function” subitems independently or jointly predicted key gait parameters, including walking velocity, step length, and cadence (R2 > 0.48).

Conclusions: All three scoring systems showed correlations with multiple key gait parameters in patients who underwent RHK. However, TESS demonstrated stronger and more consistent correlations and therefore appeared to be a more representative score of gait recovery.

Keywords

functional score / gait analysis / IDEEA / megaprosthesis

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Meng-Yu Chen, Ming-Yong Gu, Sheng-Rui Chu, Chong Li, Xue-Fei Fu, Kuan Zhang, Ji-Zhou Zeng, Yan-Cheng Liu. Correlation Between Functional Scores and Objective Gait Parameters Following Rotating Hinge Knee Megaprosthesis Reconstruction. Orthopaedic Surgery, 2026, 18 (5) : 1042-1053 DOI:10.1111/os.70300

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References

[1]

E. Pala, G. Trovarelli, T. Calabrò, A. Angelini, C. N. Abati, and P. Ruggieri, “Survival of Modern Knee Tumor Megaprostheses: Failures, Functional Results, and a Comparative Statistical Analysis,” Clinical Orthopaedics and Related Research 473, no. 3 (2015): 891–899.

[2]

L. A. Broström, M. A. Harris, M. A. Simon, D. R. Cooperman, and U. Nilsonne, “The Effect of Biopsy on Survival of Patients With Osteosarcoma,” Journal of Bone and Joint Surgery (British Volume) 61-b, no. 2 (1979): 209–212.

[3]

C. Zhang, J. Hu, K. Zhu, T. Cai, and X. Ma, “Survival, Complications and Functional Outcomes of Cemented Megaprostheses for High-Grade Osteosarcoma Around the Knee,” International Orthopaedics 42, no. 4 (2018): 927–938.

[4]

W. M. S. Sadek, W. A. Ebeid, A. E. Ghoneimy, E. Ebeid, and W. G. A. Senna, “Functional and Oncological Outcome of Patients With Distal Femoral Osteosarcoma Managed by Limb Salvage Using Modular Endoprosthesis,” Annals of Surgical Oncology 30, no. 8 (2023): 5150–5158.

[5]

L. M. Westphal, C. Theil, G. Gosheger, M. Ellerbrock, N. Deventer, and K. N. Schneider, “Patients Regularly Return to Medium- and Low-Impact Types of Sporting Activities Following Distal Femoral or Proximal Tibial Replacement After Resection of a Primary Bone Sarcoma,” Journal of Arthroplasty 39, no. 12 (2024): 3046–3055.

[6]

Y. L. Zhao, H. R. Zhang, J. Y. Zhang, and Y. C. Hu, “Postoperative Functional Assessment in Patients With Tumors Around the Knee Treated With Endoprosthetic Reconstruction: A Multicenter Retrospective Cohort Study,” Technology in Cancer Research & Treatment 22 (2023): 15330338231181283.

[7]

Y. Sharma, L. Cheung, K. K. Patterson, and A. Iaboni, “Factors Influencing the Clinical Adoption of Quantitative Gait Analysis Technologies for Adult Patient Populations With a Focus on Clinical Efficacy and Clinician Perspectives: Protocol for a Scoping Review,” JMIR Research Protocols 12 (2023): e39767.

[8]

T. Gao, H. Huang, Y. Yu, H. Liu, and Y. Ao, “Effect of Knee Extension Constraint Training on Walking Biomechanics 6 Months After Anterior Cruciate Ligament Reconstruction: A Double-Blind Randomized Controlled Clinical Trial,” Journal of Orthopaedic Surgery and Research 20, no. 1 (2025): 20.

[9]

M. Y. Gu, J. Y. Zhang, M. Y. Chen, et al., “Portable Gait Analysis of Patients With Rotating Hinge Knee Megaprosthesis Compared With Total Knee Arthroplasty,” Orthopaedic Surgery 16, no. 12 (2024): 3141–3150.

[10]

P. Pellegrino, A. Conti, A. Pautasso, et al., “Gait Analysis: Comparative Evaluation of Conventional Total Knee Replacement and Modular Distal Femoral Megaprosthesis,” Knee 27, no. 5 (2020): 1567–1576.

[11]

W. F. Enneking, W. Dunham, M. C. Gebhardt, M. Malawar, and D. J. Pritchard, “A System for the Functional Evaluation of Reconstructive Procedures After Surgical Treatment of Tumors of the Musculoskeletal System,” Clinical Orthopaedics and Related Research 286 (1993): 241–246.

[12]

M. Colangeli, D. Donati, M. G. Benedetti, et al., “Total Knee Replacement Versus Osteochondral Allograft in Proximal Tibia Bone Tumours,” International Orthopaedics 31, no. 6 (2007): 823–829.

[13]

S. Wood-Dauphinee and J. I. Williams, “Reintegration to Normal Living as a Proxy to Quality of Life,” Journal of Chronic Diseases 40, no. 6 (1987): 491–502.

[14]

S. J. Janssen, N. R. Paulino Pereira, K. A. Raskin, et al., “A Comparison of Questionnaires for Assessing Physical Function in Patients With Lower Extremity Bone Metastases,” Journal of Surgical Oncology 114, no. 6 (2016): 691–696.

[15]

L. E. Podleska, N. Kaya, F. Farzaliyev, C. Pöttgen, S. Bauer, and G. Taeger, “Lower Limb Function and Quality of Life After ILP for Soft-Tissue Sarcoma,” World Journal of Surgical Oncology 15, no. 1 (2017): 84.

[16]

A. M. Davis, J. G. Wright, J. I. Williams, C. Bombardier, A. Griffin, and R. S. Bell, “Development of a Measure of Physical Function for Patients With Bone and Soft Tissue Sarcoma,” Quality of Life Research 5, no. 5 (1996): 508–516.

[17]

J. N. Insall, L. D. Dorr, R. D. Scott, and W. N. Scott, “Rationale of the Knee Society Clinical Rating System,” Clinical Orthopaedics and Related Research 248 (1989): 13–14.

[18]

J. F. Item-Glatthorn, N. C. Casartelli, J. Petrich-Munzinger, U. K. Munzinger, and N. A. Maffiuletti, “Validity of the Intelligent Device for Energy Expenditure and Activity Accelerometry System for Quantitative Gait Analysis in Patients With Hip Osteoarthritis,” Archives of Physical Medicine and Rehabilitation 93, no. 11 (2012): 2090–2093.

[19]

L. Andreani, E. Ipponi, F. Falcinelli, et al., “Distal Femur Megaprostheses in Orthopedic Oncology: Evaluation of a Standardized Post-Operative Rehabilitation Protocol,” Health 11, no. 22 (2023): 2984.

[20]

A. Tanaka, M. Okamoto, M. Kito, et al., “Muscle Strength and Functional Recovery for Soft-Tissue Sarcoma of the Thigh: A Prospective Study,” International Journal of Clinical Oncology 28, no. 7 (2023): 922–927.

[21]

J. D. Evans, Straightforward Statistics for the Behavioral Sciences (Cole Publishing, 1996).

[22]

Y. Akiyama, K. Kazumura, S. Okamoto, and Y. Yamada, “Utilizing Inertial Measurement Units for Detecting Dynamic Stability Variations in a Multi-Condition Gait Experiment,” Sensors 24, no. 21 (2024): 7044.

[23]

S. Furtado, A. Godfrey, S. Del Din, L. Rochester, and C. Gerrand, “Are Accelerometer-Based Functional Outcome Assessments Feasible and Valid After Treatment for Lower Extremity Sarcomas?,” Clinical Orthopaedics and Related Research 478, no. 3 (2020): 482–503.

[24]

J. C. Rompen, S. J. Ham, J. P. Halbertsma, and J. R. van Horn, “Gait and Function in Patients With a Femoral Endoprosthesis After Tumor Resection: 18 Patients Evaluated 12 Years After Surgery,” Acta Orthopaedica Scandinavica 73, no. 4 (2002): 439–446.

[25]

H. Sugiura, H. Katagiri, M. Yonekawa, K. Sato, S. Yamamura, and H. Iwata, “Walking Ability and Activities of Daily Living After Limb Salvage Operations for Malignant Bone and Soft-Tissue Tumors of the Lower Limbs,” Archives of Orthopaedic and Trauma Surgery 121, no. 3 (2001): 131–134.

[26]

D. Rosenbaum, M. Brandes, J. Hardes, G. Gosheger, and R. Rödl, “Physical Activity Levels After Limb Salvage Surgery Are Not Related to Clinical Scores-Objective Activity Assessment in 22 Patients After Malignant Bone Tumor Treatment With Modular Prostheses,” Journal of Surgical Oncology 98, no. 2 (2008): 97–100.

[27]

V. Freijo, C. Navarro, B. Molina, and J. Villalba, “Low Correlation Between Gait and Quality of Life in Advanced Knee Osteoarthritis,” Journal of Functional Morphology and Kinesiology 8, no. 2 (2023): 77.

[28]

M. C. Liebensteiner, A. Herten, M. Gstoettner, M. Thaler, M. Krismer, and C. M. Bach, “Correlation Between Objective Gait Parameters and Subjective Score Measurements Before and After Total Knee Arthroplasty,” Knee 15, no. 6 (2008): 461–466.

[29]

Y. Oshima and T. Majima, “Improvement in Gait Pattern After Total Knee Arthroplasty for Knee Osteoarthritis,” Journal of Experimental Orthopaedics 12, no. 2 (2025): e70103.

[30]

M. Zhang, H. Wang, Z. Cai, et al., “A Systematic Comparative Analysis of Gait Characteristics in Patients Undergoing Total Knee Arthroplasty and Unicompartmental Knee Arthroplasty: A Review Study,” Journal of Orthopaedic Surgery and Research 19, no. 1 (2024): 821.

[31]

M. Clayer, S. Doyle, N. Sangha, and R. Grimer, “The Toronto Extremity Salvage Score in Unoperated Controls: An Age, Gender, and Country Comparison,” Sarcoma 2012 (2012): 717213.

[32]

E. Yiou, T. Caderby, A. Delafontaine, P. Fourcade, and J. L. Honeine, “Balance Control During Gait Initiation: State-Of-The-Art and Research Perspectives,” World Journal of Orthopedics 8, no. 11 (2017): 815–828.

[33]

S. M. Bruijn and J. H. van Dieën, “Control of Human Gait Stability Through Foot Placement,” Journal of the Royal Society Interface 15, no. 143 (2018): 20170816.

[34]

R. Debi, A. Mor, G. Segal, et al., “Correlation Between Single Limb Support Phase and Self-Evaluation Questionnaires in Knee Osteoarthritis Populations,” Disability and Rehabilitation 33, no. 13–14 (2011): 1103–1109.

[35]

J. Takacs, S. J. Garland, M. G. Carpenter, and M. A. Hunt, “Validity and Reliability of the Community Balance and Mobility Scale in Individuals With Knee Osteoarthritis,” Physical Therapy 94, no. 6 (2014): 866–874.

[36]

A. Leica, M. P. Sava, Z. A. Khan, R. W. Hügli, and M. T. Hirschmann, “Limitations of the Knee Society Score in Kinematically Aligned Total Knee Arthroplasty,” Journal of Experimental Orthopaedics 11, no. 3 (2024): e12054.

[37]

K. P. Vatcheva, M. Lee, J. B. McCormick, and M. H. Rahbar, “Multicollinearity in Regression Analyses Conducted in Epidemiologic Studies,” Epidemiology 6, no. 2 (2016): 227.

[38]

L. Wang, P. Song, C. Cheng, et al., “The Added Value of Combined Timed up and Go Test, Walking Speed, and Grip Strength on Predicting Recurrent Falls in Chinese Community-Dwelling Elderly,” Clinical Interventions in Aging 16 (2021): 1801–1812.

[39]

P. Khanal, L. He, G. K. Stebbings, et al., “Static One-Leg Standing Balance Test as a Screening Tool for Low Muscle Mass in Healthy Elderly Women,” Aging Clinical and Experimental Research 33, no. 7 (2021): 1831–1839.

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