Objective: Severe scoliosis is often accompanied by moderate-to-severe pulmonary dysfunction. Numerous surgical methods are available for the treatment of severe scoliosis, but the effect of each method on postoperative pulmonary function (PF) remains controversial. Apical region correction and global balance (ACGB) is an effective surgical strategy to treat severe scoliosis, using Schwab I–II osteotomies and simple one-stage surgery. Herein, we explore the effect of the ACGB surgical strategy on postoperative PF values in patients with severe scoliosis at 2-year follow-up.
Methods: Patients who underwent ACGB for scoliosis between 2015 and 2020 were enrolled, PF and radiological outcomes were evaluated preoperatively and at 2-year follow-up. PF values included forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC), and percent-predicted values (FVC% and FEV1%). Paired t-test, Pearson and Spearman correlation analyses, and multiple linear regression were used to analyze changes in PF values and associated factors.
Results: In total, 36 patients (12 male and 24 female; mean age, 20.1 years) who underwent ACGB surgery were enrolled. Preoperative PF values showed restrictive ventilatory dysfunction. At 2-year follow-up, the PF values showed significant improvements. FVC, FEV1, FVC%, and FEV1% showed mean increases of 0.72, 0.68 L, 10.3%, and 9.8%, respectively. Changes in PF values were significantly correlated with age, thoracic height, preoperative FVC%, and preoperative FEV1%.
Conclusion: ACGB significantly improves PF in patients with severe scoliosis at 2-year follow-up. The increased thoracic height may be crucial for improving PF values, while patients with poorer preoperative PF may show greater postoperative improvement.
| [1] |
H. Y. Lin, C. L. Nash, C. H. Herndon, and N. B. Andersen, “The Effect of Corrective Surgery on Pulmonary Function in Scoliosis,” Journal of Bone and Joint Surgery. American Volume 56 (1974): 1173–1179.
|
| [2] |
Y. Lin, J. Shen, L. Chen, et al., “Cardiopulmonary Function in Patients With Congenital Scoliosis: An Observational Study,” Journal of Bone and Joint Surgery. American Volume 101 (2019): 1109–1118.
|
| [3] |
K. W. Chang, “Cantilever Bending Technique for Treatment of Large and Rigid Scoliosis,” Spine (Phila Pa 1976) 28 (2003): 2452–2458.
|
| [4] |
K. Pehrsson, A. Danielsson, and A. Nachemson, “Pulmonary Function in Adolescent Idiopathic Scoliosis: A 25 Year Follow Up After Surgery or Start of Brace Treatment,” Thorax 56 (2001): 388–393.
|
| [5] |
J. M. Leaver, A. Alvik, and M. D. Warren, “Prescriptive Screening for Adolescent Idiopathic Scoliosis: A Review of the Evidence,” International Journal of Epidemiology 11 (1982): 101–111.
|
| [6] |
D. B. Bumpass, L. G. Lenke, K. H. Bridwell, et al., “Pulmonary Function Improvement After Vertebral Column Resection for Severe Spinal Deformity,” Spine (Phila Pa 1976) 39 (2014): 587–595.
|
| [7] |
H. Koller, J. Zenner, V. Gajic, O. Meier, L. Ferraris, and W. Hitzl, “The Impact of Halo-Gravity Traction on Curve Rigidity and Pulmonary Function in the Treatment of Severe and Rigid Scoliosis and Kyphoscoliosis: A Clinical Study and Narrative Review of the Literature,” European Spine Journal 21 (2012): 514–529.
|
| [8] |
V. Kumar, A. J. Vatkar, V. Baburaj, E. Najjar, and P. Bansal, “Pulmonary Function After Thoracoplasty for Adolescent Idiopathic Scoliosis: A Systematic Review and Meta-Analysis,” European Spine Journal 31 (2022): 2972–2986.
|
| [9] |
Y. Jiao, H. Tan, E. Feng, et al., “Apical Region Correction and Global Balance: A 3-Rods Surgical Strategy for the Treatment of Severe and Rigid Scoliosis,” BMC Musculoskeletal Disorders 23 (2022): 775.
|
| [10] |
F. Solla, J. L. Clément, V. Cunin, C. M. Bertoncelli, V. Fière, and V. Rampal, “Patient-Specific Rods for Thoracic Kyphosis Correction in Adolescent Idiopathic Scoliosis Surgery: Preliminary Results,” Orthopaedics & Traumatology, Surgery & Research 106 (2020): 159–165.
|
| [11] |
E. N. Obikili and I. J. Okoye, “Transverse Thoracic Diameter in Frontal Chest Radiographs of an Adult Nigerian Population,” West African Journal of Medicine 25 (2006): 186–189.
|
| [12] |
M. R. Miller, J. Hankinson, V. Brusasco, et al., “Standardisation of Spirometry,” European Respiratory Journal 26 (2005): 319–338.
|
| [13] |
O. Dede, E. K. Motoyama, C. I. Yang, et al., “Pulmonary and Radiographic Outcomes of VEPTR (Vertical Expandable Prosthetic Titanium Rib) Treatment in Early-Onset Scoliosis,” Journal of Bone and Joint Surgery. American Volume 96 (2014): 1295–1302.
|
| [14] |
V. Bullmann, T. L. Schulte, C. Schmidt, G. Gosheger, N. Osada, and U. R. Liljenqvist, “Pulmonary Function After Anterior Double Thoracotomy Approach Versus Posterior Surgery With Costectomies in Idiopathic Thoracic Scoliosis,” European Spine Journal 22, no. Suppl 2 (2013): S164–S171.
|
| [15] |
B. S. Lonner, L. Haber, C. Toombs, et al., “Is Anterior Release Obsolete or Does It Play a Role in Contemporary Adolescent Idiopathic Scoliosis Surgery? A Matched Pair Analysis,” Journal of Pediatric Orthopedics 40 (2020): e161–e165.
|
| [16] |
B. Yaszay, P. P. Jankowski, T. P. Bastrom, et al., “Progressive Decline in Pulmonary Function 5 Years Post-Operatively in Patients Who Underwent Anterior Instrumentation for Surgical Correction of Adolescent Idiopathic Scoliosis,” European Spine Journal 28 (2019): 1322–1330.
|
| [17] |
Y. J. Kim, L. G. Lenke, K. H. Bridwell, G. Cheh, J. Whorton, and B. Sides, “Prospective Pulmonary Function Comparison Following Posterior Segmental Spinal Instrumentation and Fusion of Adolescent Idiopathic Scoliosis: Is There a Relationship Between Major Thoracic Curve Correction and Pulmonary Function Test Improvement?,” Spine (Phila Pa 1976) 32 (2007): 2685–2693.
|
| [18] |
L. G. Lenke, P. T. O'Leary, K. H. Bridwell, B. A. Sides, L. A. Koester, and K. M. Blanke, “Posterior Vertebral Column Resection for Severe Pediatric Deformity: Minimum Two-Year Follow-Up of Thirty-Five Consecutive Patients,” Spine (Phila Pa 1976) 34 (2009): 2213–2221.
|
| [19] |
Z. Zhang, Z. Song, X. Yang, T. Li, N. Bi, and Y. Wang, “Is There a Correlation Between Cobb Angle and Pulmonary Function Tests at 2-Year Follow-Up in Patients With Severe Spinal Deformity Treated by Posterior Vertebral Column Resection?,” Clinical Spine Surgery 35 (2022): E483–E489.
|
| [20] |
C. Zhou, L. Liu, Y. Song, G. Feng, X. Yang, and L. Wang, “Comparison of Anterior and Posterior Vertebral Column Resection Versus Anterior and Posterior Spinal Fusion for Severe and Rigid Scoliosis,” Spine Journal 18 (2018): 948–953.
|
| [21] |
L. G. Lenke, P. O. Newton, D. J. Sucato, et al., “Complications After 147 Consecutive Vertebral Column Resections for Severe Pediatric Spinal Deformity: A Multicenter Analysis,” Spine (Phila Pa 1976) 38 (2013): 119–132.
|
| [22] |
M. C. Gupta, L. G. Lenke, S. Gupta, et al., “Perioperative Complications and Health-Related Quality of Life Outcomes in Severe Pediatric Spinal Deformity,” Spine (Phila Pa 1976) 48, no. 21 (2023): 1492–1499.
|
| [23] |
J. J. Nepple and L. G. Lenke, “Severe Idiopathic Scoliosis With Respiratory Insufficiency Treated With Preoperative Traction and Staged Anteroposterior Spinal Fusion With a 2-Level Apical Vertebrectomy,” Spine Journal 9 (2009): e9–e13.
|
| [24] |
J. Shen, G. Qiu, Y. Wang, Z. Zhang, and Y. Zhao, “Comparison of 1-Stage Versus 2-Stage Anterior and Posterior Spinal Fusion for Severe and Rigid Idiopathic Scoliosis—A Randomized Prospective Study,” Spine (Phila Pa 1976) 31 (2006): 2525–2528.
|
| [25] |
Z. Chen and L. Rong, “Comparison of Combined Anterior-Posterior Approach Versus Posterior-Only Approach in Treating Adolescent Idiopathic Scoliosis: A Meta-Analysis,” European Spine Journal 25 (2016): 363–371.
|
| [26] |
B. Ran, Q. Li, C. Li, et al., “Effect of Anterior Thoracoscopic Release Combined With the Posterior Correction Operation on the Pulmonary Function of Patients With Idiopathic Scoliosis,” Thoracic and Cardiovascular Surgeon 63 (2015): 437–442.
|
| [27] |
S. Mehrpour, R. Sorbi, R. Rezaei, and K. Mazda, “Posterior-Only Surgery With Preoperative Skeletal Traction for Management of Severe Scoliosis,” Archives of Orthopaedic and Trauma Surgery 137 (2017): 457–463.
|
| [28] |
C. Yang, H. Wang, Z. Zheng, et al., “Halo-Gravity Traction in the Treatment of Severe Spinal Deformity: A Systematic Review and Meta-Analysis,” European Spine Journal 26 (2017): 1810–1816.
|
| [29] |
J. Qiao, L. Xiao, L. Xu, et al., “Skull-Femoral Traction After Posterior Release for Correction of Adult Severe Scoliosis: Efficacy and Complications,” BMC Musculoskeletal Disorders 19 (2018): 277.
|
| [30] |
Z. Yang, Y. Liu, L. Qi, et al., “Does Preoperative Halo-Gravity Traction Reduce the Degree of Deformity and Improve Pulmonary Function in Severe Scoliosis Patients With Pulmonary Insufficiency? A Systematic Review and Meta-Analysis,” Frontiers in Medicine 8 (2021): 767238.
|
| [31] |
G. De Giorgi, G. Stella, S. Becchetti, G. Martucci, and D. Miscioscia, “Cotrel-Dubousset Instrumentation for the Treatment of Severe Scoliosis,” European Spine Journal 8 (1999): 8–15.
|
| [32] |
F. Schwab, B. Blondel, E. Chay, et al., “The Comprehensive Anatomical Spinal Osteotomy Classification,” Neurosurgery 74 (2014): 112–120.
|
| [33] |
M. Glotzbecker, C. Johnston, P. Miller, et al., “Is There a Relationship Between Thoracic Dimensions and Pulmonary Function in Early-Onset Scoliosis?,” Spine (Phila Pa 1976) 39 (2014): 1590–1595.
|
| [34] |
L. A. Karol, C. Johnston, K. Mladenov, P. Schochet, P. Walters, and R. H. Browne, “Pulmonary Function Following Early Thoracic Fusion in Non-Neuromuscular Scoliosis,” Journal of Bone and Joint Surgery. American Volume 90 (2008): 1272–1281.
|
| [35] |
K. Pehrsson, A. Nachemson, J. Olofson, K. Ström, and S. Larsson, “Respiratory Failure in Scoliosis and Other Thoracic Deformities. A Survey of Patients With Home Oxygen or Ventilator Therapy in Sweden,” Spine (Phila Pa 1976) 17 (1992): 714–718.
|
| [36] |
Y. M. Byun, T. Iida, K. Yamada, et al., “Long-Term Pulmonary Function After Posterior Spinal Fusion in Main Thoracic Adolescent Idiopathic Scoliosis,” PLoS One 15 (2020): e0235123.
|
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