Waist-To-Hip Ratio Is More Predictive of Patients-Reported Outcomes After Total Joint Arthroplasty Than Body Mass Index: A Prospective Cohort Study

Long Zhao , Yinghao Wang , Duan Wang , Zongke Zhou

Orthopaedic Surgery ›› 2025, Vol. 17 ›› Issue (12) : 3495 -3501.

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Orthopaedic Surgery ›› 2025, Vol. 17 ›› Issue (12) :3495 -3501. DOI: 10.1111/os.70201
RESEARCH ARTICLE
Waist-To-Hip Ratio Is More Predictive of Patients-Reported Outcomes After Total Joint Arthroplasty Than Body Mass Index: A Prospective Cohort Study
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Abstract

Objectives: Obesity has an important impact on the future of total joint arthroplasty (TKA). We aimed to determine whether waist-to-hip ratio (WHR) is a useful measurement in predicting postoperative outcomes associated with obesity in patients undergoing primary TKA and compared the predictive value of WHR to that of body mass index (BMI).

Methods: Prospective data from patients undergoing unilateral primary TKA from February to May 2024 were analyzed, including BMI and WHR. Outcomes included complications, hospitalization details, and 12-month patient-reported function (University of California, Los Angeles [UCLA] activity scale, the Hospital for Special Surgery [HSS] score). Multivariable regression models were used to identify significant obesity-related predictors of outcomes.

Results: A total of 195 patients were included, with the mean BMI of 28.2 ± 5.2 kg/m2 (range: 17.6–40.8) and the mean WHR of 1.03 ± 0.08 (range: 0.83–1.27). WHR was a significant predictor of wound complication (OR: 1.087, p = 0.016). Both WHR (OR: 1.153, p = 0.004) and BMI (OR: 1.058, p = 0.021) independently predicted systemic complications, with WHR explaining greater variance (R2 = 0.241 vs. 0.107 for BMI). For functional outcomes, higher WHR was associated with poorer UCLA activity scores (RR: 0.877, p = 0.012) and HSS function scores (RR: 0.921, p < 0.001), whereas BMI only showed significance for HSS function scores (RR: 0.960, p = 0.002). WHR again explained more variance in HSS function scores (R2 = 0.233 vs. 0.124). In contrast, neither WHR nor BMI correlated with surgical records, hospitalization days, or HSS pain scores (all p > 0.05).

Conclusions: The WHR demonstrates superior predictive value over BMI for perioperative complications and 12-month patient-reported functional outcomes following primary TKA. Preoperative WHR assessment may help surgeons improve risk stratification and better educate obese patients regarding postoperative expectations prior to elective TKA.

Keywords

body mass index (BMI) / total knee arthroplasty (TKA) / waist-to-hip ratio (WHR)

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Long Zhao, Yinghao Wang, Duan Wang, Zongke Zhou. Waist-To-Hip Ratio Is More Predictive of Patients-Reported Outcomes After Total Joint Arthroplasty Than Body Mass Index: A Prospective Cohort Study. Orthopaedic Surgery, 2025, 17(12): 3495-3501 DOI:10.1111/os.70201

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