Long-Term Outcomes of Triple Cannulated Compression Screws Combined With Bone Graft Sleeve Parallel Implantation of DBM Crunch Internal Fixation for the Treatment of Femoral Neck Fractures in Middle-Aged and Young Adults

Peiyuan Wang , Zhiang Zhang , Zihang Zhao , Ziping Li , Lin Liu , Kuo Zhao , Lin Jin , Wei Chen , Shiqiang Zhang , Zhiyong Hou

Orthopaedic Surgery ›› 2025, Vol. 17 ›› Issue (11) : 3211 -3221.

PDF
Orthopaedic Surgery ›› 2025, Vol. 17 ›› Issue (11) :3211 -3221. DOI: 10.1111/os.70169
RESEARCH ARTICLE
Long-Term Outcomes of Triple Cannulated Compression Screws Combined With Bone Graft Sleeve Parallel Implantation of DBM Crunch Internal Fixation for the Treatment of Femoral Neck Fractures in Middle-Aged and Young Adults
Author information +
History +
PDF

Abstract

Objective: If the appropriate internal fixation surgical method is not adopted for femoral neck fractures in young people, it may lead to serious consequences such as poor fracture healing and femoral head necrosis, affecting the quality of life and working ability of young people. Therefore, it is crucial to conduct in-depth research on the internal fixation surgical methods. This study compared the therapeutic effects of triple cannulated screws combined with a bone graft sleeve for parallel implantation of DBM Crunch internal fixation (CCSBGS) and cannulated compression screws (CCS).

Methods: Medical records on the young and middle-aged patients with femoral neck fracture treated with two different internal fixation methods from January 2020 to June 2023 were collected and retrospectively analyzed in the Trauma Emergency Center of the Third Hospital of Hebei Medical University. Two internal fixation groups are: CCSBGS group with 50 patients, 35 males and 15 females, aged (42.44 ± 14.07) years; CCS group with 80 males and 39 females, aged (41.5 ± 13.48) years. This study compared the outcome measures of two groups of patients, including Garden alignment index, Operation duration time, Intraoperative blood loss, Length of hospital stay, Postoperative complications, Femoral neck shortening, Postoperative ambulation time, Walking with sticks, Barthel score, and Harris score.

Results: There was a statistically significant difference in blood loss between the CCS group and the CCSBGS group; at the same time, the amount of bleeding in the CCS group was lower than that in the CCSBGS group (p < 0.01). During the follow-up period, there was a statistically significant difference in the incidence of osteonecrosis of the femoral head among the two groups (p < 0.05), 20 patients in the CCS group and 2 patients in the CCSBGS group developed osteonecrosis of the femoral head. At the last follow-up, the average degree of femoral neck shortening in the CCSBGS group [(0.49 ± 0.28) cm] was significantly lower than that in the CCS group [(0.87 ± 0.35) cm] (p < 0.05). Meanwhile, the postoperative ambulation time of the CCSBGS group is earlier than that of the CCS group (p < 0.05). In addition, the CCSBGS group had the highest Barthel scores [(95.50 ± 2.90)] (p < 0.05). The average Harris score in the CCSBGS group [(92.52 ± 2.41)] was higher than that in the CCS group [(90.47 ± 2.88)] (p < 0.05).

Conclusions: Compared with CCSBGS and CCS, CCSBGS shows better efficacy in terms of quicker return to weight-bearing activities, preservation of femoral neck length, reduction of the rate of osteonecrosis of the femoral head, and overall enhancement of hip function.

Keywords

bone graft sleeve / cannulated compression screws / demineralized bone matrix crunch / femoral neck fractures / young and middle-aged

Cite this article

Download citation ▾
Peiyuan Wang, Zhiang Zhang, Zihang Zhao, Ziping Li, Lin Liu, Kuo Zhao, Lin Jin, Wei Chen, Shiqiang Zhang, Zhiyong Hou. Long-Term Outcomes of Triple Cannulated Compression Screws Combined With Bone Graft Sleeve Parallel Implantation of DBM Crunch Internal Fixation for the Treatment of Femoral Neck Fractures in Middle-Aged and Young Adults. Orthopaedic Surgery, 2025, 17(11): 3211-3221 DOI:10.1111/os.70169

登录浏览全文

4963

注册一个新账户 忘记密码

References

[1]

A. V. Florschutz, J. R. Langford, G. J. Haidukewych, and K. J. Koval, “Femoral Neck Fractures: Current Management,” Journal of Orthopaedic Trauma 29, no. 3 (2015): 121–129.

[2]

N. Veronese and S. Maggi, “Epidemiology and Social Costs of Hip Fracture,” Injury 49, no. 8 (2018): 1458–1460, https://doi.org/10.1016/j.injury.2018.04.015.

[3]

M. Bhandari and M. Swiontkowski, “Management of Acute hip Fracture,” New England Journal of Medicine 377, no. 21 (November 2017): 2053–2062.

[4]

G. P. Slobogean, S. A. Sprague, T. Scott, and M. Bhandari, “Complications Following Young Femoral Neck Fractures,” Injury 46, no. 3 (March 2015): 484–491, https://doi.org/10.1016/j.injury.2014.10.010.

[5]

S. M. Zielinski, M. A. Meeuwis, M. J. Heetveld, et al., “Adherence to a Femoral Neck Fracture Treatment Guideline,” International Orthopaedics 37, no. 7 (2013): 1327–1334, https://doi.org/10.1007/s00264-013-1888-3.

[6]

M. Su, Z. He, N. Huang, X. Lin, K. Fang, and Z. Dai, “Superior Short-Term Outcomes of FNS in Combination With a Cannulated Screw in Treating Femoral Neck Fractures,” BMC Musculoskeletal Disorders 24, no. 1 (2023): 823, https://doi.org/10.1186/s12891-023-06959-w.

[7]

G. P. Slobogean, D. J. Stockton, B. Zeng, D. Wang, B. T. Ma, and A. N. Pollak, “Femoral Neck Fractures in Adults Treated With Internal Fixation: A Prospective Multicenter Chinese Cohort,” Journal of the American Academy of Orthopaedic Surgeons 25, no. 4 (April 2017): 297–303.

[8]

D. J. Stockton, K. A. Lefaivre, D. E. Deakin, G. Osterhoff, A. Yamada, and H. M. Broekhuyse, “Incidence, Magnitude, and Predictors of Shortening in Young Femoral Neck Fractures,” Journal of Orthopaedic Trauma 29, no. 9 (September 2015): e293–e298.

[9]

W. H. Harris, “Traumatic Arthritis of the Hip After Dislocation and Acetabular Fractures: Treatment by Mold Arthroplasty. An End-Result Study Using a New Method of Result Evaluation,” Journal of Bone and Joint Surgery. American Volume 51, no. 4 (1969): 737–755.

[10]

F. I. Mahoney and D. W. Barthel, “Functional Evaluation: The Barthel Index,” Maryland State Medical Journal 14 (February 1965): 61–65.

[11]

K. J. Lee, J. G. Roper, and J. C. Wang, “Demineralized Bone Matrix and Spinal Arthrodesis,” Spine Journal 5, no. 6 Suppl (2005): 217S–223S.

[12]

M. Miyazaki, H. Tsumura, J. C. Wang, and A. Alanay, “An Update on Bone Substitutes for Spinal Fusion,” European Spine Journal 18, no. 6 (June 2009): 783–799, https://doi.org/10.1007/s00586-009-0924-x.

[13]

M. R. Urist, “Bone: Formation by Autoinduction,” Science 150, no. 3698 (November 1965): 893–899.

[14]

Y. Güvercin, M. Yaylacı, A. Dizdar, et al., “Biomechanical Analysis and Solution Suggestions of Screw Replacement Scenarios in Femoral Neck Fracture Surgeries: Finite Element Method,” Orthopaedic Surgery 17, no. 2 (2025): 614–623, https://doi.org/10.1111/os.14337.

[15]

S. Cheung, K. Westerheide, and B. Ziran, “Efficacy of Contained Metaphyseal and Periarticular Defects Treated With Two Different Demineralized Bone Matrix Allografts,” International Orthopaedics 27, no. 1 (2003): 56–59.

[16]

J. L. Russell and J. E. Block, “Clinical Utility of Demineralized Bone Matrix for Osseous Defects, Arthrodesis, and Reconstruction: Impact of Processing Techniques and Study Methodology,” Orthopedics 22, no. 5 (May 1999): 524–531.

[17]

F. P. Cammisa,, G. Lowery, S. R. Garfin, et al., “Two-Year Fusion Rate Equivalency Between Grafton DBM Gel and Autograft in Posterolateral Spine Fusion: A Prospective Controlled Trial Employing a Side-By-Side Comparison in the Same Patient,” Spine 29, no. 6 (2004): 660–666.

[18]

A. R. Vaccaro, H. A. Stubbs, and J. E. Block, “Demineralized Bone Matrix Composite Grafting for Posterolateral Spinal Fusion,” Orthopedics 30, no. 7 (July 2007): 567–570.

[19]

H. W. Park, J. K. Lee, S. J. Moon, S. K. Seo, J. H. Lee, and S. H. Kim, “The Efficacy of the Synthetic Interbody Cage and Grafton for Anterior Cervical Fusion,” Spine 34, no. 17 (August 2009): E591–E595.

[20]

O. Pieske, A. Wittmann, J. Zaspel, et al., “Autologous Bone Graft Versus Demineralized Bone Matrix in Internal Fixation of Ununited Long Bones,” Journal of Trauma Management & Outcomes 3 (December 2009): 11.

[21]

R. W. Lindsey, G. W. Wood, K. K. Sadasivian, H. A. Stubbs, and J. E. Block, “Grafting Long Bone Fractures With Demineralized Bone Matrix Putty Enriched With Bone Marrow: Pilot Findings,” Orthopedics 29, no. 10 (2006): 939–941.

[22]

C. M. LeCroy, M. Rizzo, E. E. Gunneson, and J. R. Urbaniak, “Free Vascularized Fibular Bone Grafting in the Management of Femoral Neck Nonunion in Patients Younger Than Fifty Years,” Journal of Orthopaedic Trauma 16, no. 7 (August 2002): 464–472.

[23]

D. S. Damany, M. J. Parker, and A. Chojnowski, “Complications After Intracapsular Hip Fractures in Young Adults. A Meta-Analysis of 18 Published Studies Involving 564 Fractures,” Injury 36, no. 1 (2005): 131–141.

[24]

X. Li, L. Jin, G. Balian, C. T. Laurencin, and A. D. Greg, “Demineralized Bone Matrix Gelatin as Scaffold for Osteochondral Tissue Engineering,” Biomaterials 27, no. 11 (2006): 2426–2433, https://doi.org/10.1016/j.biomaterials.2005.11.040.

[25]

J. R. Mauney, S. Sjostorm, J. Blumberg, et al., “Mechanical Stimulation Promotes Osteogenic Differentiation of Human Bone Marrow Stromal Cells on 3-D Partially Demineralized Bone Scaffolds In Vitro,” Calcified Tissue International 74, no. 5 (May 2004): 458–468, https://doi.org/10.1007/s00223-003-0104-7.

[26]

M. Zlowodzki, O. Ayeni, B. A. Petrisor, and M. Bhandari, “Femoral Neck Shortening After Fracture Fixation With Multiple Cancellous Screws: Incidence and Effect on Function,” Journal of Trauma 64, no. 1 (2008): 163–169, https://doi.org/10.1097/01.ta.0000241143.71274.63.

[27]

Y. Ma, Y. Liu, Z. Liu, J. Chang, M. Li, and T. Wu, “Risk Factors of Aseptic Loosening After Total Hip Arthroplasty With Collum Femoris Preserving Stem: A Long-Term Follow-Up Study,” Orthopaedic Surgery 17 (June 2025): 2321–2330, https://doi.org/10.1111/os.70099.

[28]

M. R. Urist, Y. K. Huo, A. G. Brownell, et al., “Purification of Bovine Bone Morphogenetic Protein by Hydroxyapatite Chromatography,” Proceedings of the National Academy of Sciences of the United States of America 81, no. 2 (January 1984): 371–375.

RIGHTS & PERMISSIONS

2025 The Author(s). Orthopaedic Surgery published by Tianjin Hospital and John Wiley & Sons Australia, Ltd.

PDF

2

Accesses

0

Citation

Detail

Sections
Recommended

/