Sagittal Inclination Angle of the Graft Affects Graft Maturity and Knee Stability After Anterior Cruciate Ligament Reconstruction

Ming Li , Fangang Meng , Dianbo Long , Dorje Wencheng , Yanlin Zhong , Yan Kang , Peihui Wu , Aishan He

Orthopaedic Surgery ›› 2025, Vol. 17 ›› Issue (2) : 427 -436.

PDF
Orthopaedic Surgery ›› 2025, Vol. 17 ›› Issue (2) : 427 -436. DOI: 10.1111/os.14305
CLINICAL ARTICLE

Sagittal Inclination Angle of the Graft Affects Graft Maturity and Knee Stability After Anterior Cruciate Ligament Reconstruction

Author information +
History +
PDF

Abstract

Objective: The influence of the graft sagittal inclination angle (SIA) on knee stability, biomechanics, and graft maturity has been elucidated. However, no study has comprehensively described the effects of SIA on the aforementioned postoperative prognostic indicators. So, we aimed to determine whether the sagittal inclination angle (SIA) of a graft is associated with postoperative graft maturity, joint stability, and joint function after anterior cruciate ligament (ACL) reconstruction.

Methods: Patients who had undergone ACL reconstruction between April 2019 and February 2022 and those with intact ACL were eligible. Using magnetic resonance imaging, graft maturity was evaluated as the mean signal-to-noise quotient (SNQ) measured in three regions. Anterior tibial translation (ATT) was used to evaluate knee stability. Correlation analysis was conducted for the SIA, ATT, and clinical outcome scores. Multivariate stepwise regression analysis was used on the SIA and potential risk factors to determine their association with the graft SNQ. The SIA threshold of knee instability was calculated by receiver-operating characteristic curves.

Results: Sixty-three postoperative patients were enrolled. The SIA was significantly negatively associated with graft SNQ value. A multivariate stepwise regression analysis showed that SIA and body mass index were significant influencing factors associated with the graft SNQ. Correlations between the SIA and medial and lateral ATT were statistically significant. A larger SIA resulted in a decreased probability of medial and lateral ATT ≥ 5 mm. The SIA threshold of an increased risk of lateral ATT ≥ 5 mm was < 44.4°. A positive correlation was observed between SIA and subjective symptom subscales in the KOOS.

Conclusions: A low SIA is not conducive to graft maturation after ACL reconstruction. A larger graft SIA was correlated with better postoperative knee stability. However, the effect of the SIA on joint function was only significant in terms of symptoms. Therefore, these new findings provide new ideas for preoperative assessment and intraoperative determination of the ideal graft inclination.

Keywords

anterior cruciate ligament reconstruction / graft / maturity / sagittal inclination angle

Cite this article

Download citation ▾
Ming Li, Fangang Meng, Dianbo Long, Dorje Wencheng, Yanlin Zhong, Yan Kang, Peihui Wu, Aishan He. Sagittal Inclination Angle of the Graft Affects Graft Maturity and Knee Stability After Anterior Cruciate Ligament Reconstruction. Orthopaedic Surgery, 2025, 17(2): 427-436 DOI:10.1111/os.14305

登录浏览全文

4963

注册一个新账户 忘记密码

References

[1]

S. M. Gianotti, S. W. Marshall, P. A. Hume, and L. Bunt, “Incidence of Anterior Cruciate Ligament Injury and Other Knee Ligament Injuries: A National Population-Based Study,” Journal of Science and Medicine in Sport 12, no. 6 (2009): 622–627.

[2]

D. Hensler, C. F. Van Eck, F. H. Fu, and J. J. Irrgang, “Anatomic Anterior Cruciate Ligament Reconstruction Utilizing the Double-Bundle Technique,” Journal of Orthopaedic and Sports Physical Therapy 42, no. 3 (2012): 184–195.

[3]

K. R. Reinhardt, I. Hetsroni, and R. G. Marx, “Graft Selection for Anterior Cruciate Ligament Reconstruction: A Level I Systematic Review Comparing Failure Rates and Functional Outcomes,” Orthopedic Clinics of North America 41, no. 2 (2010): 249–262.

[4]

C. Pedneault, C. Laverdière, A. Hart, M. Boily, M. Burman, and P. A. Martineau, “Evaluating the Accuracy of Tibial Tunnel Placement After Anatomic Single-Bundle Anterior Cruciate Ligament Reconstruction,” American Journal of Sports Medicine 47, no. 13 (2019): 3187–3194.

[5]

J. R. Giffin and C. D. Harner, “Failed Anterior Cruciate Ligament Surgery: Overview of the Problem,” American Journal of Knee Surgery 14, no. 3 (2001): 185–192.

[6]

J. Hashemi, N. Chandrashekar, H. Mansouri, et al., “Shallow Medial Tibial Plateau and Steep Medial and Lateral Tibial Slopes: New Risk Factors for Anterior Cruciate Ligament Injuries,” American Journal of Sports Medicine 38, no. 1 (2010): 54–62.

[7]

Y. Li, L. Hong, H. Feng, et al., “Posterior Tibial Slope Influences Static Anterior Tibial Translation in Anterior Cruciate Ligament Reconstruction: A Minimum 2-Year Follow-Up Study,” American Journal of Sports Medicine 42, no. 4 (2014): 927–933.

[8]

A. Schneider, C. Arias, C. Bankhead, R. Gaillard, S. Lustig, and E. Servien, “Greater Medial Tibial Slope Is Associated With Increased Anterior Tibial Translation in Females With an ACL-Deficient Knee,” Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA 28, no. 6 (2020): 1901–1908.

[9]

K. D. Illingworth, D. Hensler, Z. M. Working, J. A. Macalena, S. Tashman, and F. H. Fu, “A Simple Evaluation of Anterior Cruciate Ligament Femoral Tunnel Position: The Inclination Angle and Femoral Tunnel Angle,” American Journal of Sports Medicine 39, no. 12 (2011): 2611–2618.

[10]

B. S. Kyung, J. G. Kim, M. Chang, et al., “Anatomic Double-Bundle Reconstruction Techniques Result in Graft Obliquities That Closely Mimic the Native Anterior Cruciate Ligament Anatomy,” American Journal of Sports Medicine 41, no. 6 (2013): 1302–1309.

[11]

J. C. Reid, B. Yonke, and M. Tompkins, “The Angle of Inclination of the Native ACL in the Coronal and Sagittal Planes,” Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA 25, no. 4 (2017): 1101–1105.

[12]

K. Hagiwara, M. Terauchi, K. Hatayama, S. Yanagisawa, T. Ohsawa, and M. Kimura, “Sagittal Inclination Angle of Graft Is Associated With Knee Stability After Anatomic Anterior Cruciate Ligament Reconstruction,” Arthroscopy: The Journal of Arthroscopic & Related Surgery 37, no. 8 (2021): 2533–2541.

[13]

T. Oshima, S. Putnis, S. Grasso, A. Klasan, and D. A. Parker, “Graft Size and Orientation Within the Femoral Notch Affect Graft Healing at 1 Year After Anterior Cruciate Ligament Reconstruction,” American Journal of Sports Medicine 48, no. 1 (2020): 99–108.

[14]

F. Zampeli, A. Ntoulia, D. Giotis, et al., “Correlation Between Anterior Cruciate Ligament Graft Obliquity and Tibial Rotation During Dynamic Pivoting Activities in Patients With Anatomic Anterior Cruciate Ligament Reconstruction: An In Vivo Examination,” Arthroscopy: The Journal of Arthroscopic & Related Surgery 28, no. 2 (2012): 234–246.

[15]

A. Weiler, G. Peters, J. Mäurer, F. N. Unterhauser, and N. P. Südkamp, “Biomechanical Properties and Vascularity of an Anterior Cruciate Ligament Graft Can Be Predicted by Contrast-Enhanced Magnetic Resonance Imaging. A Two-Year Study in Sheep,” American Journal of Sports Medicine 29, no. 6 (2001): 751–761.

[16]

H. Li, H. Tao, S. Cho, S. Chen, Z. Yao, and S. Chen, “Difference in Graft Maturity of the Reconstructed Anterior Cruciate Ligament 2 Years Postoperatively: A Comparison Between Autografts and Allografts in Young Men Using Clinical and 3.0-T Magnetic Resonance Imaging Evaluation,” American Journal of Sports Medicine 40, no. 7 (2012): 1519–1526.

[17]

P. Van Dyck, K. Zazulia, C. Smekens, C. H. W. Heusdens, T. Janssens, and J. Sijbers, “Assessment of Anterior Cruciate Ligament Graft Maturity With Conventional Magnetic Resonance Imaging: A Systematic Literature Review,” Orthopaedic Journal of Sports Medicine 7, no. 6 (2019): 2325967119849012.

[18]

S. S. Chiu, “The Anterior Tibial Translocation Sign,” Radiology 239, no. 3 (2006): 914–915.

[19]

B. Haughom, W. Schairer, R. B. Souza, D. Carpenter, C. B. Ma, and X. Li, “Abnormal Tibiofemoral Kinematics Following ACL Reconstruction Are Associated With Early Cartilage Matrix Degeneration Measured by MRI T1rho,” Knee 19, no. 4 (2012): 482–487.

[20]

Ž. Snoj, O. Zupanc, K. Stražar, and V. Salapura, “A Descriptive Study of Potential Effect of Anterior Tibial Translation, Femoral Tunnel and Anterior Cruciate Ligament Graft Inclination on Clinical Outcome and Degenerative Changes,” International Orthopaedics 41, no. 4 (2017): 789–796.

[21]

T. N. Vahey, J. E. Hunt, and K. D. Shelbourne, “Anterior Translocation of the Tibia at MR Imaging: A Secondary Sign of Anterior Cruciate Ligament Tear,” Radiology 187, no. 3 (1993): 817–819.

[22]

R. O’brien, “A Caution Regarding Rules of Thumb for Variance Inflation Factors,” Quality and Quantity 41, no. 5 (2007): 673–690.

[23]

R. Fluss, D. Faraggi, and B. Reiser, “Estimation of the Youden Index and Its Associated Cutoff Point,” Biometrical Journal 47, no. 4 (2005): 458–472.

[24]

J. N. Mandrekar, “Receiver Operating Characteristic Curve in Diagnostic Test Assessment,” Journal of Thoracic Oncology 5, no. 9 (2010): 1315–1316.

[25]

H. Li, S. Chen, H. Tao, H. Li, and S. Chen, “Correlation Analysis of Potential Factors Influencing Graft Maturity After Anterior Cruciate Ligament Reconstruction,” Orthopaedic Journal of Sports Medicine 2, no. 10 (2014): 2325967114553552.

[26]

W. P. Chan, C. Peterfy, R. C. Fritz, and H. K. Genant, “MR Diagnosis of Complete Tears of the Anterior Cruciate Ligament of the Knee: Importance of Anterior Subluxation of the Tibia,” AJR. American Journal of Roentgenology 162, no. 2 (1994): 355–360.

[27]

M. J. Tanaka, K. J. Jones, A. M. Gargiulo, et al., “Passive Anterior Tibial Subluxation in Anterior Cruciate Ligament-Deficient Knees,” American Journal of Sports Medicine 41, no. 10 (2013): 2347–2352.

[28]

H. K. Kim, T. Laor, N. J. Shire, J. A. Bean, and B. J. Dardzinski, “Anterior and Posterior Cruciate Ligaments at Different Patient Ages: MR Imaging Findings,” Radiology 247, no. 3 (2008): 826–835.

[29]

S. Hosseinzadeh and A. M. Kiapour, “Age-Related Changes in ACL Morphology During Skeletal Growth and Maturation Are Different Between Females and Males,” Journal of Orthopaedic Research 39, no. 4 (2021): 841–849.

[30]

S. Claes, P. Verdonk, R. Forsyth, and J. Bellemans, “The ‘ligamentization’ process in anterior cruciate ligament reconstruction: what happens to the human graft? A systematic review of the literature,” American Journal of Sports Medicine 39, no. 11 (2011): 2476–2483.

[31]

E. Cavaignac, V. Marot, M. Faruch, et al., “Hamstring Graft Incorporation According to the Length of the Graft Inside Tunnels,” American Journal of Sports Medicine 46, no. 2 (2018): 348–356.

[32]

M. Hofbauer, F. Soldati, P. Szomolanyi, et al., “Hamstring Tendon Autografts Do Not Show Complete Graft Maturity 6 Months Postoperatively After Anterior Cruciate Ligament Reconstruction,” Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA 27, no. 1 (2019): 130–136.

[33]

R. Lin, Q. Zhong, X. Wu, et al., “Randomized Controlled Trial of All-Inside and Standard Single-Bundle Anterior Cruciate Ligament Reconstruction With Functional, MRI-Based Graft Maturity and Patient-Reported Outcome Measures,” BMC Musculoskeletal Disorders 23, no. 1 (2022): 289.

[34]

Y. Ma, C. D. Murawski, A. A Rahnemai-Azar, C. Maldjian, A. D. Lynch, and F. H. Fu, “Graft Maturity of the Reconstructed Anterior Cruciate Ligament 6 Months Postoperatively: A Magnetic Resonance Imaging Evaluation of Quadriceps Tendon With Bone Block and Hamstring Tendon Autografts,” Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA 23, no. 3 (2015): 661–668.

[35]

I. A. Khowailed, J. Petrofsky, E. Lohman, N. Daher, and O. Mohamed, “17β-Estradiol Induced Effects on Anterior Cruciate Ligament Laxness and Neuromuscular Activation Patterns in Female Runners,” Journal of Women’s Health (2002) 24, no. 8 (2015): 670–680.

[36]

M. Miyawaki, D. Hensler, K. D. Illingworth, J. J. Irrgang, and F. H. Fu, “Signal Intensity on Magnetic Resonance Imaging After Allograft Double-Bundle Anterior Cruciate Ligament Reconstruction,” Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA 22, no. 5 (2014): 1002–1008.

[37]

A. W. H Ng, J. F. Griffith, E. H. Y. Hung, K. Y. Law, E. P. Y. Ho, and P. S. H. Yung, “Can MRI Predict the Clinical Instability and Loss of the Screw Home Phenomenon Following ACL Tear?,” Clinical Imaging 37, no. 1 (2013): 116–123.

[38]

Y. Kato, S. J. M. Ingham, S. Kramer, P. Smolinski, A. Saito, and F. H. Fu, “Effect of Tunnel Position for Anatomic Single-Bundle ACL Reconstruction on Knee Biomechanics in a Porcine Model,” Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA 18, no. 1 (2010): 2–10.

[39]

R. P. A. Janssen and S. U. Scheffler, “Intra-Articular Remodelling of Hamstring Tendon Grafts After Anterior Cruciate Ligament Reconstruction,” Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA 22, no. 9 (2014): 2102–2108.

[40]

E. Fujimoto, Y. Sumen, Y. Urabe, et al., “An Early Return to Vigorous Activity May Destabilize Anterior Cruciate Ligaments Reconstructed With Hamstring Grafts,” Archives of Physical Medicine and Rehabilitation 85, no. 2 (2004): 298–302.

[41]

J. Ménétrey, V. B. Duthon, T. Laumonier, and D. Fritschy, ““Biological Failure” of the Anterior Cruciate Ligament Graft,” Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA 16, no. 3 (2008): 224–231.

RIGHTS & PERMISSIONS

2024 The Author(s). Orthopaedic Surgery published by Tianjin Hospital and John Wiley & Sons Australia, Ltd.

AI Summary AI Mindmap
PDF

167

Accesses

0

Citation

Detail

Sections
Recommended

AI思维导图

/