Sutureless clampless partial nephrectomy: where do we stand? A narrative review

Abstract

This review aims to evaluate the current literature on sutureless clampless partial nephrectomy (sl-oc PN) and assess its potential advantages in terms of renal function preservation, oncological safety, and perioperative outcomes. We conducted a literature search across multiple databases, including MEDLINE, PubMed, and Embase, selecting studies published in the last 10 years that reported on clampless and sutureless partial nephrectomy in cohorts of 10 or more patients. Ten studies from 2015 to 2025 were included, mostly involving tumors with low RENAL (Radius, Exophytic/endophytic properties, Nearness of tumor to collecting system or sinus, Anterior/posterior descriptor, and Location relative to polar lines) scores (< 5). Key outcomes analyzed were estimated blood loss, positive surgical margin rates, major complications (Clavien-Dindo grade ≥ 3), and postoperative renal function changes. Overall, the sutureless clampless technique demonstrated comparable oncological safety, low complication rates, and favorable preservation of renal function. These findings support the feasibility and safety of sl-oc PN, with careful case selection being essential.

Keywords

Minimally invasive surgery / RAPN / laparoscopic / renal cancer / kidney cancer

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