SADI-S: personal experience after 8 years
Francesco Pennestrì , Livia Palmieri , Priscilla Francesca Procopio , Pierpaolo Gallucci , Antonio Laurino , Francesca Prioli , Francesco Greco , Luigi Ciccoritti , Piero Giustacchini , Annamaria Martullo , Giulio Perrone , Luca Sessa , Giulia Salvi , Amerigo Iaconelli , Barbara Aquilanti , Giuseppe Marincola , Caterina Guidone , Esmeralda Capristo , Geltrude Mingrone , Carmela De Crea , Marco Raffaelli
Mini-invasive Surgery ›› 2025, Vol. 9 ›› Issue (1) : 16
SADI-S: personal experience after 8 years
Aim: Biliopancreatic diversion with duodenal switch (BPD-DS) was simplified by the single anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S). It reduces the surgical duration and postoperative complications while maintaining effectiveness in weight loss and mitigating comorbidities.
Methods: This study aims to report personal experiences regarding short- and medium-term outcomes 8 years after the introduction of SADI-S in clinical practice and compare these with the current literature evidence.
Results: At our center, 4,854 bariatric procedures were executed from July 2016 to October 2024, with 157 (3.2%) patients undergoing SADI-S/SADI. This included 104 (66.2%) primary SADI-Ss, 8 (5.1%) conversions to SADI-S, and 45 (28.7%) SADI procedures. Conversion to SADI-S was planned in eight out of 157 after adjustable gastric banding (6 cases) and Roux-en-Y gastric bypass (2 cases). Median age and preoperative body mass index (BMI) were 46 (40-53) years and 51.6 (46.7-56.7) kg/m2, respectively. The median surgical duration was 120 min, with an interquartile range of 100 to 160 min. Reoperation was required for two of the four patients (2.5%) who experienced early postoperative complications. Furthermore, 5 (3.1%) patients developed late complications. At a median follow-up of 23 (12-31) months, the median %TWL, %EWL, and BMI were 42 (29.3-52.4), 82 (59.1-99.4), and 27.3 (21.2-33) kg/m2, respectively. Seven years of follow-up were eligible in 13 out of 157 patients: median %TWL, %EWL and BMI were 43 (40.1-52.7), 69 (66.4-85.6), and 31.1 (26.2-32.2) kg/m2, respectively.
Conclusion: SADI-S is regarded as an effective primary and conversion operation, balancing bariatric and metabolic outcomes with early and late complications.
SADI-S / SADI / bariatric outcomes / long-term outcomes / learning curve / robotic SADI-S / complications
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