SADI-S: personal experience after 8 years

Francesco Pennestrì , Livia Palmieri , Priscilla Francesca Procopio , Pierpaolo Gallucci , Antonio Laurino , Francesca Prioli , Francesco Greco , Luigi Ciccoritti , Piero Giustacchini , Annamaria Martullo , Giulio Perrone , Luca Sessa , Giulia Salvi , Amerigo Iaconelli , Barbara Aquilanti , Giuseppe Marincola , Caterina Guidone , Esmeralda Capristo , Geltrude Mingrone , Carmela De Crea , Marco Raffaelli

Mini-invasive Surgery ›› 2025, Vol. 9 ›› Issue (1) : 16

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Mini-invasive Surgery ›› 2025, Vol. 9 ›› Issue (1) :16 DOI: 10.20517/2574-1225.2025.03
Original Article

SADI-S: personal experience after 8 years

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Abstract

Aim: Biliopancreatic diversion with duodenal switch (BPD-DS) was simplified by the single anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S). It reduces the surgical duration and postoperative complications while maintaining effectiveness in weight loss and mitigating comorbidities.

Methods: This study aims to report personal experiences regarding short- and medium-term outcomes 8 years after the introduction of SADI-S in clinical practice and compare these with the current literature evidence.

Results: At our center, 4,854 bariatric procedures were executed from July 2016 to October 2024, with 157 (3.2%) patients undergoing SADI-S/SADI. This included 104 (66.2%) primary SADI-Ss, 8 (5.1%) conversions to SADI-S, and 45 (28.7%) SADI procedures. Conversion to SADI-S was planned in eight out of 157 after adjustable gastric banding (6 cases) and Roux-en-Y gastric bypass (2 cases). Median age and preoperative body mass index (BMI) were 46 (40-53) years and 51.6 (46.7-56.7) kg/m2, respectively. The median surgical duration was 120 min, with an interquartile range of 100 to 160 min. Reoperation was required for two of the four patients (2.5%) who experienced early postoperative complications. Furthermore, 5 (3.1%) patients developed late complications. At a median follow-up of 23 (12-31) months, the median %TWL, %EWL, and BMI were 42 (29.3-52.4), 82 (59.1-99.4), and 27.3 (21.2-33) kg/m2, respectively. Seven years of follow-up were eligible in 13 out of 157 patients: median %TWL, %EWL and BMI were 43 (40.1-52.7), 69 (66.4-85.6), and 31.1 (26.2-32.2) kg/m2, respectively.

Conclusion: SADI-S is regarded as an effective primary and conversion operation, balancing bariatric and metabolic outcomes with early and late complications.

Keywords

SADI-S / SADI / bariatric outcomes / long-term outcomes / learning curve / robotic SADI-S / complications

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Francesco Pennestrì, Livia Palmieri, Priscilla Francesca Procopio, Pierpaolo Gallucci, Antonio Laurino, Francesca Prioli, Francesco Greco, Luigi Ciccoritti, Piero Giustacchini, Annamaria Martullo, Giulio Perrone, Luca Sessa, Giulia Salvi, Amerigo Iaconelli, Barbara Aquilanti, Giuseppe Marincola, Caterina Guidone, Esmeralda Capristo, Geltrude Mingrone, Carmela De Crea, Marco Raffaelli. SADI-S: personal experience after 8 years. Mini-invasive Surgery, 2025, 9(1): 16 DOI:10.20517/2574-1225.2025.03

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