PDF
Abstract
Endoscopic submucosal dissection (ESD) is widely performed to treat superficial colorectal tumors because it enables en bloc resection of various types of lesions. However, ESD sometimes leads to deleterious adverse events, such as perforation and delayed bleeding. Therefore, determining the precise preoperative indication for ESD is vitally important. Furthermore, small lesions with fibrosis and semi-large lesions can be managed using underwater endoscopic mucosal resection, and the “true” indication for ESD is for the treatment of larger lesions, for which ESD carries a higher risk. Here, we reviewed the devices, techniques (i.e., pocket creation method, water pressure method, and clip and flap method), traction (i.e., clip with line, pulley method, and clip with ring), suturing (i.e., line-assisted complete closure, loop clip, clip-on-clip closure method, mucosal incision around the mucosal defect, and hand-suturing), and countermeasures to address complications (i.e., bleeding after ESD, perforation, and post-ESD coagulation syndrome) that facilitate easier and safer ESD.
Keywords
Colorectal tumors, endoscopic submucosal dissection, traction
/
suturing, pocket creation
Cite this article
Download citation ▾
Satoki Shichijo, Yoji Takeuchi.
Devices, techniques, traction, suturing, and countermeasures for endoscopic submucosal dissection complications.
Mini-invasive Surgery, 2022, 6(1): 19 DOI:10.20517/2574-1225.2021.121
| [1] |
Oka S,Saito Y.Colorectal Endoscopic Resection Standardization Implementation Working Group of the Japanese Society for Cancer of the Colon and Rectum, Tokyo, JapanLocal recurrence after endoscopic resection for large colorectal neoplasia: a multicenter prospective study in Japan.Am J Gastroenterol2015;110:697-707
|
| [2] |
Tanaka S,Saito Y.Japan Gastroenterological Endoscopy Society guidelines for colorectal endoscopic submucosal dissection/endoscopic mucosal resection.Dig Endosc2020;32:219-39
|
| [3] |
Binmoeller KF,Shah J,Kane S.“Underwater” EMR without submucosal injection for large sessile colorectal polyps (with video).Gastrointest Endosc2012;75:1086-91
|
| [4] |
Shichijo S,Uedo N.Management of local recurrence after endoscopic resection of neoplastic colonic polyps.World J Gastrointest Endosc2018;10:378-82 PMCID:PMC6323499
|
| [5] |
Ohmori M,Iwagami H.Propensity score-matched analysis of endoscopic resection for recurrent colorectal neoplasms: a pilot study.J Gastroenterol Hepatol2021;36:2568-74
|
| [6] |
Zhang X,Nithyanand S.Learning curve for endoscopic submucosal dissection with an untutored, prevalence-based approach in the United States.Clin Gastroenterol Hepatol2020;18:580-8.e1
|
| [7] |
Rönnow C,Toth E.Endoscopic submucosal dissection of 301 large colorectal neoplasias: outcome and learning curve from a specialized center in Europe.Endosc Int Open2018;06:E1340-8 PMCID:PMC6221812
|
| [8] |
De Ceglie A,Mangiavillano B.Endoscopic mucosal resection and endoscopic submucosal dissection for colorectal lesions: a systematic review.Crit Rev Oncol Hematol2016;104:138-55
|
| [9] |
Takeuchi Y,Tanaka S.Factors associated with technical difficulties and adverse events of colorectal endoscopic submucosal dissection: retrospective exploratory factor analysis of a multicenter prospective cohort.Int J Colorectal Dis2014;29:1275-84
|
| [10] |
Ohya T,Sumiyama K.Balloon overtube-guided colorectal endoscopic submucosal dissection.World J Gastroenterol2009;15:6086-90 PMCID:PMC2797666
|
| [11] |
Yamashina T,Sakamoto H.Balloon-assisted endoscopy facilitates endoscopic submucosal dissection of difficult superficial proximal colon tumors.Endoscopy2018;50:800-8
|
| [12] |
Sakaguchi Y,Fujishiro M.Evaluation of endoscopic submucosal dissection using a new endosurgical knife DN-D2718B: a first clinical feasibility study.Endosc Int Open2017;5:E670-4 PMCID:PMC5500109
|
| [13] |
Yamashina T,Nagai K.Scissor-type knife significantly improves self-completion rate of colorectal endoscopic submucosal dissection: single-center prospective randomized trial.Dig Endosc2017;29:322-9
|
| [14] |
Hayashi Y,Takahashi H.Pocket-creation method of endoscopic submucosal dissection to achieve en bloc resection of giant colorectal subpedunculated neoplastic lesions.Endoscopy2014;46 Suppl 1 UCTN:E421-2
|
| [15] |
Yamashina T,Hayashi Y.Prospective randomized trial comparing the pocket-creation method and conventional method of colorectal endoscopic submucosal dissection.Gastrointest Endosc2020;92:368-79
|
| [16] |
Akasaka T,Uedo N,Iishi H.“Underwater” endoscopic submucosal dissection for superficial esophageal neoplasms.Gastrointest Endosc2017;85:251-2
|
| [17] |
Harada H,Murakami D.Saline-pocket endoscopic submucosal dissection for superficial colorectal neoplasms: a randomized controlled trial (with video).Gastrointest Endosc2019;90:278-87
|
| [18] |
Ozeki Y,Ikeda R.Safety and efficacy of water pressure endoscopic submucosal dissection for colorectal tumors with submucosal fibrosis (with video).Gastrointest Endosc2021;94:607-17.e2
|
| [19] |
Yahagi N,Sasaki M,Uraoka T.Water pressure method for duodenal endoscopic submucosal dissection.Endoscopy2017;49:E227-8
|
| [20] |
Kato M,Sasaki M.Water pressure method for duodenal endoscopic submucosal dissection (with video).Gastrointest Endosc2021;93:942-9
|
| [21] |
Yamamoto K,Nakabori T,Ichiba M.Endoscopic submucosal dissection using endoclips to assist in mucosal flap formation (novel technique: “clip flap method”).Endoscopy2012;44 Suppl 2 UCTN:E334-5
|
| [22] |
Yamamoto K,Saiki H.Endoscopic submucosal dissection for large superficial colorectal tumors using the “clip-flap method”.Endoscopy2015;47:262-5
|
| [23] |
Yamamoto K,Nishida T.Effective use of the “clip-flap” method for the endoscopic submucosal dissection of a difficult-to-approach superficial gastric tumor.Endoscopy2015;47 Suppl 1 UCTN:E318-9
|
| [24] |
Yoshida M,Suzuki S.CONNECT-G Study GroupConventional versus traction-assisted endoscopic submucosal dissection for gastric neoplasms: a multicenter, randomized controlled trial (with video).Gastrointest Endosc2018;87:1231-40
|
| [25] |
Yoshida M,Nonaka S.CONNECT-E Study GroupConventional versus traction-assisted endoscopic submucosal dissection for large esophageal cancers: a multicenter, randomized controlled trial (with video).Gastrointest Endosc2020;91:55-65.e2
|
| [26] |
Yamasaki Y,Hanaoka N.A novel traction method using an endoclip attached to a nylon string during colonic endoscopic submucosal dissection.Endoscopy2015;47 Suppl 1 UCTN:E238-9
|
| [27] |
Yamasaki Y,Uedo N.Efficacy of traction-assisted colorectal endoscopic submucosal dissection using a clip-and-thread technique: a prospective randomized study.Dig Endosc2018;30:467-76
|
| [28] |
Shichijo S,Takeuchi Y.Case of colonic adenoma involving a diverticulum resected by a traction-assisted endoscopic submucosal dissection technique.Dig Endosc2017;29:729-30
|
| [29] |
Rieder E,Martinec DV.The suture-pulley method for endolumenal triangulation in endoscopic submucosal dissection.Endoscopy2011;43 Suppl 2 UCTN:E319-20
|
| [30] |
Aihara H,Ryou M,Ryan MB.Facilitating endoscopic submucosal dissection: the suture-pulley method significantly improves procedure time and minimizes technical difficulty compared with conventional technique: an ex vivo study (with video).Gastrointest Endosc2014;80:495-502 PMCID:PMC4426966
|
| [31] |
Oyama T.Counter traction makes endoscopic submucosal dissection easier.Clin Endosc2012;45:375-8 PMCID:PMC3521938
|
| [32] |
Shichijo S,Takeuchi Y,Ishihara R.Pulley traction-assisted colonic endoscopic submucosal dissection affords good visibility of submucosal layer.VideoGIE2018;3:358-60 PMCID:PMC6206323
|
| [33] |
Shichijo S,Matsuno K.Pulley traction-assisted colonic endoscopic submucosal dissection: a retrospective case series.Dig Dis2019;37:473-7
|
| [34] |
Mori H,Nishiyama N,Matsunaga T.Novel effective and repeatedly available ring-thread counter traction for safer colorectal endoscopic submucosal dissection.Surg Endosc2017;31:3040-7 PMCID:PMC5487838
|
| [35] |
Ritsuno H,Osada T.Prospective clinical trial of traction device-assisted endoscopic submucosal dissection of large superficial colorectal tumors using the S-O clip.Surg Endosc2014;28:3143-9
|
| [36] |
Sakamoto N,Shibuya T.The facilitation of a new traction device (S-O clip) assisting endoscopic submucosal dissection for superficial colorectal neoplasms.Endoscopy2008;40 Suppl 2:E94-5
|
| [37] |
Sakamoto N,Shibuya T.Endoscopic submucosal dissection of large colorectal tumors by using a novel spring-action S-O clip for traction (with video).Gastrointest Endosc2009;69:1370-4
|
| [38] |
Osada T,Shibuya T.“Loops-attached rubber band” facilitation of endoscopic submucosal dissection of superficial colorectal neoplasm.Endoscopy2008;40 Suppl 2:E101-2
|
| [39] |
Harada H,Murakami D.Clinical impact of prophylactic clip closure of mucosal defects after colorectal endoscopic submucosal dissection.Endosc Int Open2017;5:E1165-71 PMCID:PMC5698008
|
| [40] |
Kato M,Yamasaki Y.Technical feasibility of line-assisted complete closure technique for large mucosal defects after colorectal endoscopic submucosal dissection.Endosc Int Open2017;5:E11-6 PMCID:PMC5361877
|
| [41] |
Yamasaki Y,Iwatsubo T.Line-assisted complete closure for a large mucosal defect after colorectal endoscopic submucosal dissection decreased post-electrocoagulation syndrome.Dig Endosc2018;30:633-41
|
| [42] |
Sakamoto N,Matsumoto K.“Loop Clip”, a new closure device for large mucosal defects after EMR and ESD.Endoscopy2008;40 Suppl 2:E97-8
|
| [43] |
Nomura T,Sugimoto S,Kamei A.Clip-on-clip closure method for a mucosal defect after colorectal endoscopic submucosal dissection: a prospective feasibility study.Surg Endosc2020;34:1412-6
|
| [44] |
Otake Y,Sakamoto T.New closure technique for large mucosal defects after endoscopic submucosal dissection of colorectal tumors (with video).Gastrointest Endosc2012;75:663-7
|
| [45] |
Abe S,Tanaka Y.A novel endoscopic hand-suturing technique for defect closure after colorectal endoscopic submucosal dissection: a pilot study.Endoscopy2020;52:780-5
|
| [46] |
Kantsevoy SV,Mitrakov AA.Endoscopic suturing closure of large mucosal defects after endoscopic submucosal dissection is technically feasible, fast, and eliminates the need for hospitalization (with videos).Gastrointest Endosc2014;79:503-7
|
| [47] |
Yamashina T,Akasaka T.Comparison of underwater vs conventional endoscopic mucosal resection of intermediate-size colorectal polyps.Gastroenterology2019;157:451-61.e2
|
| [48] |
Yamasaki Y,Oka S.Feasibility of underwater clip closure for large mucosal defects after colorectal endoscopic submucosal dissection.Digestion2019;99:327-32
|
| [49] |
Takeuchi Y,Matsui F,Uedo N.Indication, strategy and outcomes of endoscopic submucosal dissection for colorectal neoplasm.Dig Endosc2012;24 Suppl 1:100-4
|
| [50] |
Niimi K,Kodashima S.Long-term outcomes of endoscopic submucosal dissection for colorectal epithelial neoplasms.Endoscopy2010;42:723-9
|
| [51] |
Oka S,Kanao H.Current status in the occurrence of postoperative bleeding, perforation and residual/local recurrence during colonoscopic treatment in Japan.Dig Endosc2010;22:376-80
|
| [52] |
Saito Y,Yamaguchi Y.A prospective, multicenter study of 1111 colorectal endoscopic submucosal dissections (with video).Gastrointest Endosc2010;72:1217-25
|
| [53] |
Toyonaga T,Man-I M,Azuma T.Principles of quality controlled endoscopic submucosal dissection with appropriate dissection level and high quality resected specimen.Clin Endosc2012;45:362-74 PMCID:PMC3521937
|
| [54] |
Nakajima T,Tanaka S.Current status of endoscopic resection strategy for large, early colorectal neoplasia in Japan.Surg Endosc2013;27:3262-70
|
| [55] |
Lee EJ,Lee SH.Endoscopic submucosal dissection for colorectal tumors--1,000 colorectal ESD cases: one specialized institute’s experiences.Surg Endosc2013;27:31-9
|
| [56] |
Veitch AM,Gershlick AH.Endoscopy in patients on antiplatelet or anticoagulant therapy, including direct oral anticoagulants: British Society of Gastroenterology (BSG) and European Society of Gastrointestinal Endoscopy (ESGE) guidelines.Gut2016;65:374-89 PMCID:PMC4789831
|
| [57] |
Acosta RD,Chandrasekhara V.ASGE Standards of Practice CommitteeThe management of antithrombotic agents for patients undergoing GI endoscopy.Gastrointest Endosc2016;83:3-16
|
| [58] |
Chan FKL,Reddy N.Management of patients on antithrombotic agents undergoing emergency and elective endoscopy: joint Asian Pacific Association of Gastroenterology (APAGE) and Asian Pacific Society for Digestive Endoscopy (APSDE) practice guidelines.Gut2018;67:405-17 PMCID:PMC5868286
|
| [59] |
Douketis JD,Dunn AS.The perioperative management of antithrombotic therapy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).Chest2008;133:299S-339S
|
| [60] |
Kato M,Hokimoto S.Guidelines for gastroenterological endoscopy in patients undergoing antithrombotic treatment: 2017 appendix on anticoagulants including direct oral anticoagulants.Dig Endosc2018;30:433-40
|
| [61] |
Fujimoto K,Kato M.Japan Gastroenterological Endoscopy SocietyGuidelines for gastroenterological endoscopy in patients undergoing antithrombotic treatment.Dig Endosc2014;26:1-14
|
| [62] |
Rechenmacher SJ.Bridging anticoagulation: primum non nocere.J Am Coll Cardiol2015;66:1392-403
|
| [63] |
Takizawa K,Gotoda T.Routine coagulation of visible vessels may prevent delayed bleeding after endoscopic submucosal dissection--an analysis of risk factors.Endoscopy2008;40:179-83
|
| [64] |
Liu M,Wang Y,Xu H.Effect of prophylactic closure on adverse events after colorectal endoscopic submucosal dissection: a meta-analysis.J Gastroenterol Hepatol2020;35:1869-77
|
| [65] |
Taku K,Fu KI.Iatrogenic perforation associated with therapeutic colonoscopy: a multicenter study in Japan.J Gastroenterol Hepatol2007;22:1409-14
|
| [66] |
Repici A,Strangio G,Fagoonee S.Endoscopic mucosal resection for early colorectal neoplasia: pathologic basis, procedures, and outcomes.Dis Colon Rectum2009;52:1502-15
|
| [67] |
Nakahira H,Garcia JS.Line-assisted endoscopic complete closure of a large perforation during colonic endoscopic submucosal dissection.Endoscopy2018;50:E32-3
|
| [68] |
Iwatsubo T,Yamasaki Y.Differences in clinical course of intraprocedural and delayed perforation caused by endoscopic submucosal dissection for colorectal neoplasms: a retrospective study.Dig Dis2019;37:53-62
|
| [69] |
Xiao YF,Yu J.Endoscopic treatment of delayed colon perforation: the enteroscopy overtube approach.Endoscopy2014;46:503-8
|
| [70] |
Kuwabara H,Tachikawa J,Arimoto J.Endoscopic closure using over-the-scope clip for delayed colonic perforation after hybrid endoscopic submucosal dissection.Endoscopy2020;52:E368-9
|
| [71] |
Nagami Y,Kanamori A.Endoscopic closure using polyglycolic acid sheets for delayed perforation after colonic endoscopic submucosal dissection.Endoscopy2020;52:E11-2
|
| [72] |
Yamashina T,Uedo N.Features of electrocoagulation syndrome after endoscopic submucosal dissection for colorectal neoplasm.J Gastroenterol Hepatol2016;31:615-20
|
| [73] |
Arimoto J,Kato S.Risk factors for post-colorectal endoscopic submucosal dissection (ESD) coagulation syndrome: a multicenter, prospective, observational study.Endosc Int Open2018;6:E342-9 PMCID:PMC5842075
|
| [74] |
Ito S,Imai K.Risk factors of post-endoscopic submucosal dissection electrocoagulation syndrome for colorectal neoplasm.J Gastroenterol Hepatol2018;33:2001-6
|
| [75] |
Hong MJ,Lee SY,Park HS.Prevalence and clinical features of coagulation syndrome after endoscopic submucosal dissection for colorectal neoplasms.Dig Dis Sci2015;60:211-6
|
| [76] |
Jung D,Jahng J,Park H.Risk of electrocoagulation syndrome after endoscopic submucosal dissection in the colon and rectum.Endoscopy2013;45:714-7
|
| [77] |
Lee SP,Kim JH.A randomized controlled trial of prophylactic antibiotics in the prevention of electrocoagulation syndrome after colorectal endoscopic submucosal dissection.Gastrointest Endosc2017;86:349-57.e2
|
| [78] |
Shichijo S,Shimodate Y.Kansai Endoscopic Device Selection Conference in Kansai Research GroupPerformance of perioperative antibiotics against post-endoscopic submucosal dissection coagulation syndrome: a multicenter randomized controlled trial.Gastrointest Endosc2022;95:349-59
|
| [79] |
Fukuda H,Shoji A.Curative value of underwater endoscopic mucosal resection for submucosally invasive colorectal cancer.J Gastroenterol Hepatol2021;36:2471-8
|
| [80] |
Inoue T,Yamasaki Y.Underwater endoscopic mucosal resection versus endoscopic submucosal dissection for 20-30 mm colorectal polyps.J Gastroenterol Hepatol2021;36:2549-57
|
| [81] |
Zhou PH,Qin XY.Endoscopic full-thickness resection without laparoscopic assistance for gastric submucosal tumors originated from the muscularis propria.Surg Endosc2011;25:2926-31
|
| [82] |
Yu C,Fan C.Long-term outcomes of endoscopic resection of gastric GISTs.Surg Endosc2017;31:4799-804
|
| [83] |
Shichijo S,Yanagimoto Y.Endoscopic full-thickness resection of gastric gastrointestinal stromal tumor: a Japanese case series.Ann Gastroenterol2019;32:593-9 PMCID:PMC6826078
|
| [84] |
Andrisani G,Martino M.Endoscopic full-thickness resection of superficial colorectal neoplasms using a new over-the-scope clip system: a single-centre study.Dig Liver Dis2017;49:1009-13
|
| [85] |
Li P,Gong S,Li W.Efficacy and safety of endoscopic full-thickness resection in the colon and rectum using an over-the-scope device: a meta-analysis.Surg Endosc2021;35:249-59
|
| [86] |
Noguchi T,Nishimura T,Awazu K.Enhancement of the safety and efficacy of colorectal endoscopic submucosal dissection using a CO2 laser.Lasers Med Sci2020;35:421-7
|
| [87] |
Tsiamoulos ZP,Morris S,Saunders BP.A novel multimodality endoscopic device for colonic submucosal dissection using a combination of bipolar radiofrequency and microwave modalities.Endoscopy2016;48:271-6
|
| [88] |
Chiu PWY,Phee SJ.Colonic endoscopic submucosal dissection using a novel robotic system (with video).Gastrointest Endosc2021;93:1172-7
|
| [89] |
Turiani Hourneaux de Moura D,Jirapinyo P.Robot-assisted endoscopic submucosal dissection versus conventional ESD for colorectal lesions: outcomes of a randomized pilot study in endoscopists without prior ESD experience (with video).Gastrointest Endosc2019;90:290-8
|