Overview of gastroesophageal junction cancers

Abstract

Oesophageal and gastroesophageal junction (GEJ) malignancy is the fastest growing cancer in the Western population. This together with the deadly nature of the disease has attracted increased attention from doctors and researchers alike. The increasing incidence has been primarily attributed to the increase in rates of obesity that in turn causes increased gastroesophageal reflux disease leading to Barrett’s oesophagus and eventually adenocarcinoma of the oesophagus especially at the GEJ. We discuss the epidemiology, risk factors and the management of GEJ tumours.

Keywords

Cardioesophageal / gastroesophageal / upper gastrointestinal / cancer / tumour

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