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Abstract
Aim: The advent of minimally invasive abdominal and thoracic surgeries has led to a meaningful reduction in complication and mortality rates among patients undergoing esophagectomy, especially when used for the treatment of benign diseases such as megaesophagus.
Methods: Two hundred thirty-one patients, 152 (65.8%) men and 79 (34.2%) women, with a mean age of 52.46 (19-80) years, were treated for advanced megaesophagus between September 1996 and October 2016. Two hundred ten patients (90.91%) had chagasic megaesophagus and 21 patients (9.09%) had idiopathic megaesophagus.
Results: Immediate complications were observed in 37 patients (16.01%): hemopneumothorax in 22 cases (9.52%), gastric stasis in 11 (4.76%), cervical fistula in 11 (4.76%), dysphonia in 18 (7.8%), and mediastinitis in 1 case (0.43%). Two patients (0.86%) died: 1 patient with a pacemaker died of cardiorespiratory arrest on postoperative day 12 and the other patient died of mediastinitis on day 28. Our standardized protocol includes nutritional and pulmonary outpatient care.
Conclusion: With a standardized multidisciplinary protocol and a team adequately trained in laparoscopy, minimally invasive esophagectomy is an excellent option for the treatment of advanced megaesophagus. The technique is easily standardized and reproducible, and provides excellent postoperative outcomes.
Keywords
Advanced megaesophagus
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vagal preservation
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transhiatal esophagectomy
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laparoscopic esophagectomy
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Eduardo Crema, Júverson Alves Terra Júnior, Guilherme Azevedo Terra, Celso Junior de Oliveira Teles, Alex Augusto da Silva.
Minimally invasive esophagectomy in achalasia: a more liberal approach to esophageal resection.
Mini-invasive Surgery, 2017, 1(1): 160-6 DOI:10.20517/2574-1225.2017.26
| [1] |
Banki F,DeMeester SR,Balaji NS,Bremner CG,DeMeester TR.Vagal-sparing esophagectomy: a more physiologic alternative..Ann Surg2002;236:324-35; discussion 335-6 PMCID:PMC1422586
|
| [2] |
Eckardt VF,Bernhard G.Life expectancy, complications, and causes of death in patients with achalasia: results of a 33-year follow-up investigation..Eur J Gastroenterol Hepatol2008;20:956-60
|
| [3] |
Banbury MK,Goldblum JR,Baker ME,Rybicki LA.Esophagectomy with gastric reconstruction for achalasia..J Thorac Cardiovasc Surg1999;117:1077-84
|
| [4] |
Wang D,Sun K.The digestive functions of the stomach after esophagectomy with vagus nerve preserved or severed in esophageal cancer patients: a comparative study..Zhonghua Zhong Liu Za Zhi2000;22:414-6(in Chinese)
|
| [5] |
Eduardo C,Lima VG,Silva AA.Microflora in chagasic megaesophagus..Rev Soc Bras Med Trop2002;35:39-42(in Portuguese)
|
| [6] |
Crema E,Junqueira IS,Terra Júnior JA.Prevalence study of esophageal HPV infection in patients with megaesophagus and correlation with in situ and 24-hour PH measurement..Bras J Video-Sur2010;3:181-5
|
| [7] |
Fonseca FM,Rocha AM,Crema E,Ramirez LE.Seroprevalence of Helicobacter pylori infection in chagasic and nonchagasic patients from the same geographical region of Brazil..Rev Soc Bras Med Trop2012;45:194-8
|
| [8] |
DePaula AL,Ferreira EA,Grecco E.Laparoscopic transhiatal esophagectomy with esophagogastroplasty..Surg Laparosc Endosc1995;5:1-5
|
| [9] |
Crema E,Terra JAJr.Laparoscopic transhiatal subtotal esophagectomy for the treatment of advanced megaesophagus..Ann Thorac Surg2005;80:1196-201
|
| [10] |
Crema E,Sousa RC,Silva BF,Silva AV.Laparoscopic transhiatal esophagectomy for the treatment of advanced megaesophagus. An analysis of 60 cases..Rev Col Bras Cir2009;36:118-22(in Portuguese)
|
| [11] |
Crema E,Werneck AM,Silva AA.Manometric and radiologic aspects of Chagas' megaesophagus: the importance to its surgical treatment..Rev Soc Bras Med Trop2003;36:665-9(in Portuguese)
|
| [12] |
Molena D,Stem M.Hospitalization for esophageal achalasia in the United States..World J Gastrointest Endosc2015;7:1096-102 PMCID:PMC4580951
|
| [13] |
Loviscek MF,Hinojosa MW,Pajitnov D,Pellegrini CA.Recurrent dysphagia after Heller myotomy: is esophagectomy always the answer?.J Am Coll Surg2013;216:736-43; discussion 743-4
|
| [14] |
Orringer MB.Esophageal resection for achalasia: indications and results..Ann Thorac Surg1989;47:340-5
|
| [15] |
Devaney EJ,Orringer MB.Esophagectomy for achalasia: patient selection and clinical experience..Ann Thorac Surg2001;72:854-8
|
| [16] |
Rodgers M,O'Rourke RW,Diggs B.Case volume as a predictor of inpatient mortality after esophagectomy..Arch Surg2007;142:829-39
|
| [17] |
Patti MG,Fisichella PM,Yamada H,Way LW.Laparoscopic Heller myotomy and Dor fundoplication for achalasia: analysis of successes and failures..Arch Surg2001;136:870-7
|
| [18] |
Csendes A,Burdiles P,Csendes P.Very late results of esophagomyotomy for patients with achalasia: clinical, endoscopic, histologic, manometric, and acid reflux studies in 67 patients for a mean follow-up of 190 months..Ann Surg2006;243:196-203 PMCID:PMC1448918
|
| [19] |
Leeuwenburgh I,Alderliesten J,Looman CW,Kuipers EJ.Long-term esophageal cancer risk in patients with primary achalasia: a prospective study..Am J Gastroenterol2010;105:2144-9
|
| [20] |
Li SY,Shen LP,Zhao XY,Liu HT.Meta analysis on etiological relationship between human papillomavirus and esophageal carcinoma..Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi2009;23:85-7(in Chinese)
|
| [21] |
Devaney EJ,Orringer MB.Esophagectomy for achalasia: patient selection and clinical experience..Ann Thorac Surg2001;72:854-8
|
| [22] |
Molena D.Surgical management of end-stage achalasia..Semin Thorac Cardiovasc Surg2012;24:19-26
|
| [23] |
de Oliveira GC,Coelho-Neto Jde S,Lopes LR.Esophageal mucosal resection versus esophagectomy: a comparative study of surgical results in patients with advanced megaesophagus..Arq Bras Cir Dig2015;28:28-31(in English, Portuguese) PMCID:PMC4739237
|
| [24] |
Crema E,Franciscon PM,Martins Júnior A,Silva AA.Prevalence of cholelithiasis in patients with chagasic megaesophagus..Rev Soc Bras Med Trop2011;44:324-6
|
| [25] |
Zamuner M,Aquino JL.Standardized clinical pathways for esophagectomy are not a reality in Brazil, even with a high prevalence of esophageal cancer and achalasia..Arq Bras Cir Dig2015;28:190-2 PMCID:PMC4737360
|
| [26] |
Herbella FA,Moreno DG,Del Grande JC.Vagal integrity in vagal-sparing esophagectomy: a cadaveric study..Dis Esophagus2006;19:406-9
|
| [27] |
Peyre CG,Rizzetto C,Tang AL,Leers JM,Hagen JA.Vagal-sparing esophagectomy: the ideal operation for intramucosal adenocarcinoma and barrett with high-grade dysplasia..Ann Surg2007;246:665-71; discussion 671-4
|
| [28] |
Borovikova LV,Zhang M,Botchkina GI,Wang H,Eaton JW.Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin..Nature2000;405:458-62
|
| [29] |
van Westerloo DJ,Florquin S,Bruno MJ,Tracey KJ.The cholinergic anti-inflammatory pathway regulates the host response during septic peritonitis..J Infect Dis2005;191:2138-48
|
| [30] |
Crema E,Junqueira IS,Terra GA,Silva AA.Vagus nerve integrity in patients who underwent laparoscopic esophagectomy for the treatment of megaesophagus..Braz J Video-Sur2013;6:097-102
|
| [31] |
Oliveira GC,Andreollo NA.Surgically treated megaesophagus: epidemiological profile of patients operated in the Clinical Hospital of the State University of Campinas between 1989 and 2005..Rev Soc Bras Med Trop2008;41:183-8(in Portuguese)
|