An Ultrasound-Programmable System for Highly Sensitive and Spatiotemporally Controlled Drug Release in Deep Tissues

Chenyao Wu , Lili Xia , Wei Feng

MEDCOMM - Biomaterials and Applications ›› 2025, Vol. 4 ›› Issue (2) : e70014

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MEDCOMM - Biomaterials and Applications ›› 2025, Vol. 4 ›› Issue (2) : e70014 DOI: 10.1002/mba2.70014
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An Ultrasound-Programmable System for Highly Sensitive and Spatiotemporally Controlled Drug Release in Deep Tissues

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Chenyao Wu, Lili Xia, Wei Feng. An Ultrasound-Programmable System for Highly Sensitive and Spatiotemporally Controlled Drug Release in Deep Tissues. MEDCOMM - Biomaterials and Applications, 2025, 4(2): e70014 DOI:10.1002/mba2.70014

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References

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W. Wang, Y. Shi, W. Chai, et al., “H-Bonded Organic Frameworks as Ultrasound-Programmable Delivery Platform,” Nature 638, no. 8050 (2025): 401–410.

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M. T. Manzari, Y. Shamay, H. Kiguchi, N. Rosen, M. Scaltriti, and D. A. Heller, “Targeted Drug Delivery Strategies for Precision Medicines,” Nature Reviews Materials 6, no. 4 (2021): 351–370.

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A. Gavish, M. Tyler, A. C. Greenwald, et al., “Hallmarks of Transcriptional Intratumour Heterogeneity Across a Thousand Tumours,” Nature 618, no. 7965 (2023): 598–606.

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S. Huo, P. Zhao, Z. Shi, et al., “Mechanochemical Bond Scission for the Activation of Drugs,” Nature Chemistry 13, no. 2 (2021): 131–139.

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L. Chen, R. Nixon, and G. De Bo, “Force-Controlled Release of Small Molecules With a Rotaxane Actuator,” Nature 628, no. 8007 (2024): 320–325.

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2025 The Author(s). MedComm – Biomaterials and Applications published by John Wiley & Sons Australia, Ltd on behalf of Sichuan International Medical Exchange & Promotion Association (SCIMEA).

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