
Design of strong and tough biofibers and their biomedical applications
Dongpeng Sun, Yuan Zheng, Anxun Zhang, Jing Wang, Yao Xiao, Dong Chen
MEDCOMM - Biomaterials and Applications ›› 2025, Vol. 4 ›› Issue (1) : e70005.
Design of strong and tough biofibers and their biomedical applications
Strong and tough biofibers, which have comparable mechanical performances with conventional synthetic fibers derived from petrochemicals, have demonstrated superior advantages in sustainability and biocompatibility and have provided innovative solutions for various areas over synthetic fibers. Studies on strong and tough biofibers have addressed the growing demand for sustainable products and biomedical applications. Here, recent advances in strong and tough biofibers are summarized and discussed, including their materials, spinning methods, strengthening strategies, and various applications. Four natural materials commonly used for biofibers are introduced first, including spider silk, silkworm silk, chitin, and cellulose, and then four different spinning techniques developed to prepare strong and tough biofibers are summarized, including dry spinning, wet spinning, 3D printing, and microfluidic spinning. Strengthening strategies, such as dual crosslinking and post treatment, are applied to further improve the mechanical performances of biofibers, and their applications, especially in clothing, suture, would dressing, tissue engineering, and sensor, are discussed in detail. Continuous innovations in strong and tough biofibers hold a great promise for driving further advancements and offering solutions to related global challenges.
biofiber / fiber / spinning / strong / tough
[1] |
CuiY, GongH, WangY, Li D, BaiH. A thermally insulating textile inspired by polar bear hair. Adv Mater. 2018;30(14):e1706807.
CrossRef
Google scholar
|
[2] |
ShaghalehH, XuX, WangS. Current progress in production of biopolymeric materials based on cellulose, cellulose nanofibers, and cellulose derivatives. RSC Adv. 2018;8(2):825-842.
CrossRef
Google scholar
|
[3] |
IsmailSO, AkpanE, DhakalHN. Review on natural plant fibres and their hybrid composites for structural applications: recent trends and future perspectives. Composites Part C: Open Access. 2022;9(10):100322.
CrossRef
Google scholar
|
[4] |
SuJ, LiuB, HeH, et al. Engineering high strength and super-toughness of unfolded structural proteins and their extraordinary anti-adhesion performance for abdominal hernia repair. Adv Mater. 2022;34(19):e2200842.
CrossRef
Google scholar
|
[5] |
ShengJ, WuJ, YinX, et al. Synergetic treatment of oxygen microcapsules and lenvatinib for enhanced therapy of HCC by alleviating hypoxia condition and activating anti-tumor immunity. Chin Chem Lett. 2023;34(4):107738.
CrossRef
Google scholar
|
[6] |
KimT, KimD, ParkY. Recent progress in regenerated fibers for “green” textile products. J Clean Prod. 2022;376(17):134226.
CrossRef
Google scholar
|
[7] |
TranHA, HoangTT, MaraldoA, et al. Emerging silk fibroin materials and their applications: new functionality arising from innovations in silk crosslinking. Mater Today. 2023;65(21):244-259.
CrossRef
Google scholar
|
[8] |
SunX, WangX, SunF, et al. Textile waste fiber regeneration via a green chemistry approach: a molecular strategy for sustainable fashion. Adv Mater. 2021;33(48):e2105174.
CrossRef
Google scholar
|
[9] |
SandinG, PetersGM. Environmental impact of textile reuse and recycling – a review. J Clean Prod. 2018;184(9):353-365.
CrossRef
Google scholar
|
[10] |
LiC, WuJ, ShiH, et al. Fiber-based biopolymer processing as a route toward sustainability. Adv Mater. 2022;34(1):e2105196.
CrossRef
Google scholar
|
[11] |
NiinimäkiK, PetersG, DahlboH, Perry P, RissanenT, GwiltA. The environmental price of fast fashion. Nat Rev Earth Environ. 2020;1(4):189-200.
CrossRef
Google scholar
|
[12] |
RameshM, DeepaC, KumarLR, Sanjay M, SiengchinS. Life-cycle and environmental impact assessments on processing of plant fibres and its bio-composites: a critical review. J Indust Textiles. 2022;51(4):5518S-5542S.
CrossRef
Google scholar
|
[13] |
MannGS, SinghLP, KumarP, Singh S. Green composites: a review of processing technologies and recent applications. J Thermoplast Compos Mater. 2020;33(8):1145-1171.
CrossRef
Google scholar
|
[14] |
ShekarHSS, Ramachandra M. Green composites: a review. Mater Today: Proc. 2018;5(1):2518-2526.
CrossRef
Google scholar
|
[15] |
ShangL, YuY, LiuY, ChenZ, KongT, Zhao Y. Spinning and applications of bioinspired fiber systems. ACS Nano. 2019;13(3):2749-2772.
CrossRef
Google scholar
|
[16] |
XuZ, WuM, YeQ, ChenD, LiuK, BaiH. Spinning from nature: engineered preparation and application of high-performance bio-based fibers. Engineering. 2022;14:100-112.
CrossRef
Google scholar
|
[17] |
YangC, ChenL, ZhangR, Chen D, ArriagaLR, WeitzDA. Local high-density distributions of phospholipids induced by the nucleation and growth of smectic liquid crystals at the interface. Chin Chem Lett. 2022;33(8):3973-3976.
CrossRef
Google scholar
|
[18] |
LiuY, RenJ, LingS. Bioinspired and biomimetic silk spinning. Comp Commun. 2019;13:85-96.
CrossRef
Google scholar
|
[19] |
WangY, GuoJ, ZhouL, et al. Design, fabrication, and function of silk-based nanomaterials. Adv Funct Mater. 2018;28(52):1805305.
CrossRef
Google scholar
|
[20] |
ZhouG, ShaoZ, KnightDP, Yan J, ChenX. Silk fibers extruded artificially from aqueous solutions of regenerated bombyx mori silk fibroin are tougher than their natural counterparts. Adv Mater. 2009;21(3):366-370.
CrossRef
Google scholar
|
[21] |
XiaoY, YangC, ZhaiX, et al. Bioinspired tough and strong fibers with hierarchical core-shell structure. Adv Mater Interfaces. 2023;10(2):2201962.
CrossRef
Google scholar
|
[22] |
XiaoY, YangC, GuoB, et al. Bioinspired strong and tough organic–inorganic hybrid fibers. Small Struct. 2023;4(10):2300080.
CrossRef
Google scholar
|
[23] |
XiaoY, YangZ, GuoB, et al. Strong and tough biofibers designed by dual crosslinking for sutures. Adv Funct Mater. 2024;34(14):2313131.
CrossRef
Google scholar
|
[24] |
HuX, Shmelev K, SunL, et al. Regulation of silk material structure by temperature-controlled water vapor annealing. Biomacromolecules. 2011;12(5):1686-1696.
CrossRef
Google scholar
|
[25] |
GaoH-L, ZhaoR, CuiC, et al. Bioinspired hierarchical helical nanocomposite macrofibers based on bacterial cellulose nanofibers. Natl Sci Rev. 2019;7(1):73-83.
CrossRef
Google scholar
|
[26] |
YangL, WuY, YangF, Wu X, CaiY, ZhangJ. A wood textile fiber made from natural wood. J Mater Sci. 2021;56(27):15122-15133.
CrossRef
Google scholar
|
[27] |
WuM, ShaoZ, ZhaoN, et al. Biomimetic, knittable aerogel fiber for thermal insulation textile. Science. 2023;382(6677):1379-1383.
CrossRef
Google scholar
|
[28] |
SunD, ZhengL, XuX, et al. Multi-functional stimuli-responsive biomimetic flower assembled from CLCE and MOF-based pedals. Chin Chem Lett. 2023;34(1):107208.
CrossRef
Google scholar
|
[29] |
LuH, ZhangY, ZhuM, et al. Intelligent perceptual textiles based on ionic-conductive and strong silk fibers. Nat Commun. 2024;15(1):3289.
CrossRef
Google scholar
|
[30] |
LiuM, ZhangY, LiuK, et al. Biomimicking antibacterial opto-electro sensing sutures made of regenerated silk proteins. Adv Mater. 2021;33(1):2004733.
CrossRef
Google scholar
|
[31] |
HuW, WangZ, XuY, et al. Remodeling of inherent antimicrobial nanofiber dressings with melamine-modified fibroin into neoskin. J Mater Chem B. 2019;7(21):3412-3423.
CrossRef
Google scholar
|
[32] |
MengC, SongJ, MalekmohammadiS, et al. Hierarchical porous poly (L-lactic acid) fibrous vascular graft with controllable architectures and stable structure. Mater Des. 2024;240:112829.
CrossRef
Google scholar
|
[33] |
ChangH, LiuQ, ZimmermanJF, et al. Recreating the heart’s helical structure-function relationship with focused rotary jet spinning. Science. 2022;377(6602):180-185.
CrossRef
Google scholar
|
[34] |
MamidiN, García RG, MartínezJDH, et al. Recent advances in designing fibrous biomaterials for the domain of biomedical, clinical, and environmental applications. ACS Biomater Sci Eng. 2022;8(9):3690-3716.
CrossRef
Google scholar
|
[35] |
MiguelSP, Figueira DR, SimõesD, et al. Electrospun polymeric nanofibres as wound dressings. Colloids Surf B. 2018;169:60-71.
CrossRef
Google scholar
|
[36] |
LiY, WeiC, JiangY, et al. Continuous preparation of chitosan-based self-powered sensing fibers recycled from wasted materials for smart home applications. Adv Fiber Mater. 2022;4(6):1584-1594.
CrossRef
Google scholar
|
[37] |
DickoC, Vollrath F, KenneyJM. Spider silk protein refolding is controlled by changing pH. Biomacromolecules. 2004;5(3):704-710.
CrossRef
Google scholar
|
[38] |
DouY, WangZ-P, HeW, et al. Artificial spider silk from ion-doped and twisted core-sheath hydrogel fibres. Nat Commun. 2019;10(1):5293.
CrossRef
Google scholar
|
[39] |
SponnerA, VaterW, MonajembashiS, UngerE, GrosseF, WeisshartK. Composition and hierarchical organisation of a spider silk. PLoS One. 2007;2(10):e998.
CrossRef
Google scholar
|
[40] |
HeW, QianD, WangY, et al. A protein-like nanogel for spinning hierarchically structured artificial spider silk. Adv Mater. 2022;7(34):2201843.
CrossRef
Google scholar
|
[41] |
KonoN, Nakamura H, MoriM, et al. Multicomponent nature underlies the extraordinary mechanical properties of spider dragline silk. Proc Natl Acad Sci. 2021;118(31):e2107065118.
CrossRef
Google scholar
|
[42] |
WangQ, Schniepp HC. Strength of recluse spider’s silk originates from nanofibrils. ACS Macro Lett. 2018;7(11):1364-1370.
CrossRef
Google scholar
|
[43] |
RisingA, Johansson J. Toward spinning artificial spider silk. Nat Chem Biol. 2015;11(5):309-315.
CrossRef
Google scholar
|
[44] |
VollrathF. Strength and structure of spiders’ silks. Rev Mol Biotechnol. 2000;74(2):67-83.
CrossRef
Google scholar
|
[45] |
QinD, WangM, ChengW, et al. Spidroin-mimetic engineered protein fibers with high toughness and minimized batch-to-batch variations through β-sheets co-assembly. Angew Chem Int Ed. 2024;63(15):e202400595.
CrossRef
Google scholar
|
[46] |
DomiganLJ, Andersson M, AlbertiKA, et al. Carbonic anhydrase generates a pH gradient in bombyx mori silk glands. Insect Biochem Mol Biol. 2015;65:100-106.
CrossRef
Google scholar
|
[47] |
OmenettoFG, KaplanDL. New opportunities for an ancient material. Science. 2010;329(5991):528-531.
CrossRef
Google scholar
|
[48] |
VepariC, KaplanDL. Silk as a biomaterial. Prog Polym Sci. 2007;32(8):991-1007.
CrossRef
Google scholar
|
[49] |
ZhangY, ChenC, QiuY, et al. Meso-reconstruction of silk fibroin based on molecular and nano-templates for electronic skin in medical applications. Adv Funct Mater. 2021;31(21):2100150.
CrossRef
Google scholar
|
[50] |
ChenS, LiuM, HuangH, Cheng L, ZhaoHP. Mechanical properties of bombyx mori silkworm silk fibre and its corresponding silk fibroin filament. Mater Des. 2019;181:108077.
CrossRef
Google scholar
|
[51] |
LingS, JinK, KaplanDL, Buehler MJ. Ultrathin free-standing bombyx mori silk nanofibril membranes. Nano Lett. 2016;16(6):3795-3800.
CrossRef
Google scholar
|
[52] |
RockwoodDN, PredaRC, YücelT, Wang X, LovettML, KaplanDL. Materials fabrication from bombyx mori silk fibroin. Nat Protoc. 2011;6(10):1612-1631.
CrossRef
Google scholar
|
[53] |
HollandC, NumataK, Rnjak-KovacinaJ, et al. The biomedical use of silk. Adv Healthc Mater. 2019;8(1):1800465.
|
[54] |
YaoX, ZouS, FanS, et al Bioinspired silk fibroin materials. Mater Today Bio. 2022;16:100381.
CrossRef
Google scholar
|
[55] |
KohL-D, ChengY, TengC-P, et al. Structures, mechanical properties and applications of silk fibroin materials. Prog Polym Sci. 2015;46:86-110.
CrossRef
Google scholar
|
[56] |
HuangW, LingS, LiC, Omenetto FG, KaplanDL. Silkworm silk-based materials and devices generated using bio-nanotechnology. Chem Soc Rev. 2018;47(17):6486-6504.
CrossRef
Google scholar
|
[57] |
ZhouZ, ZhangS, CaoY, Marelli B, XiaX, TaoTH. Engineering the future of silk materials through advanced manufacturing. Adv Mater. 2018;30(33):1706983.
CrossRef
Google scholar
|
[58] |
KlemmD, Cranston ED, FischerD, et al. Nanocellulose as a natural source for groundbreaking applications in materials science. Mater Today. 2018;21(7):720-748.
CrossRef
Google scholar
|
[59] |
KlemmD, KramerF, MoritzS, et al. Nanocelluloses: a new family of nature-based materials. Angew Chem Int Ed. 2011;50(24):5438-5466.
CrossRef
Google scholar
|
[60] |
MittalN, AnsariF, Gowda VK, et al. Multiscale control of nanocellulose assembly. ACS Nano. 2018;12(7):6378-6388.
CrossRef
Google scholar
|
[61] |
KontturiE, Laaksonen P, LinderMB, et al. Advanced materials through assembly of nanocelluloses. Adv Mater. 2018;30(24):e1703779.
CrossRef
Google scholar
|
[62] |
NishinoT, TakanoK, NakamaeK. Elastic modulus of the crystalline regions of cellulose polymorphs. J Polym Sci Part B Polym Phys. 1995;33(11):1647-1651.
CrossRef
Google scholar
|
[63] |
El-HosseinyF, PageDH. The mechanical properties of single wood pulp fibres: theories of strength. Fibre Sci Technol. 1975;8(1):21-31.
CrossRef
Google scholar
|
[64] |
TashiroK, Kobayashi M. Theoretical evaluation of three-dimensional elastic constants of native and regenerated celluloses. Polymer. 1991;32(8):1516-1526.
CrossRef
Google scholar
|
[65] |
WangB, QiuS, ChenZ, et al. Assembling nanocelluloses into fibrous materials and their emerging applications. Carbohydr Polym. 2023;299:120008.
CrossRef
Google scholar
|
[66] |
TsurkanMV, Voronkina A, KhrunykY, WysokowskiM, Petrenko I, EhrlichH. Progress in chitin analytics. Carbohydr Polym. 2021;252:117204.
CrossRef
Google scholar
|
[67] |
DanielE, Hamblin MR. Chitin and chitosan: production and application of versatile biomedical nanomaterials. Int J Adv Res (Indore). 2016;4(3):411-427.
|
[68] |
Ravi KumarMNV. A review of chitin and chitosan applications. Reactive Funct Polym. 2000;46(1):1-27.
CrossRef
Google scholar
|
[69] |
LatgéJP. The cell wall: a carbohydrate armour for the fungal cell. Mol Microbiol. 2007;66(2):279-290.
CrossRef
Google scholar
|
[70] |
WangM, ChenLJ, NiJ, WengJ, YueCY. Manufacture and evaluation of bioactive and biodegradable materials and scaffolds for tissue engineering. J Mater Sci: Mater Med. 2001;12(10):855-860.
CrossRef
Google scholar
|
[71] |
ManjulaK, PodileAR. Chitin-supplemented formulations improve biocontrol and plant growth promoting efficiency of Bacillus subtilis AF 1. Can J Microbiol. 2001;47(7):618-625.
CrossRef
Google scholar
|
[72] |
Zainol AbidinNA, KorminF, Zainol AbidinNA, Mohamed AnuarNAF, Abu Bakar MF. The potential of insects as alternative sources of chitin. Int J Mol Sci. 2020;21(14):4978.
CrossRef
Google scholar
|
[73] |
HahnT, TafiE, PaulA, Salvia R, FalabellaP, ZibekS. Current state of chitin purification and chitosan production from insects. J Chem Technol Biotechnol. 2020;95(11):2775-2795.
CrossRef
Google scholar
|
[74] |
AhmadSI, AhmadR, KhanMS, et al. Chitin and its derivatives: structural properties and biomedical applications. Int J Biiol Macromol. 2020;164:526-539.
CrossRef
Google scholar
|
[75] |
JinH-J, KaplanDL. Mechanism of silk processing in insects and spiders. Nature. 2003;424(6952):1057-1061.
CrossRef
Google scholar
|
[76] |
LiuS, CuiZ, LiuZ, ZhaoW, ZhouX. Research progress on spider-inspired tough fibers. Chin J Chem. 2023;41(23):3401-3418.
CrossRef
Google scholar
|
[77] |
MuX, WangY, GuoC, et al. 3D printing of silk protein structures by aqueous solvent-directed molecular assembly. Macromol Biosci. 2020;20(1):1900191.
CrossRef
Google scholar
|
[78] |
LingS, QinZ, LiC, HuangW, KaplanDL, Buehler MJ. Polymorphic regenerated silk fibers assembled through bioinspired spinning. Nat Commun. 2017;8(1):1387.
CrossRef
Google scholar
|
[79] |
ZhangC, XiaoP, ZhangD, et al. Wet-spinning knittable hygroscopic organogel fibers toward moisture-capture-enabled multifunctional devices. Adv Fiber Mater. 2023;5(2):588-602.
CrossRef
Google scholar
|
[80] |
ChengJ, JunY, QinJ, LeeSH. Electrospinning versus microfluidic spinning of functional fibers for biomedical applications. Biomaterials. 2017;114:121-143.
CrossRef
Google scholar
|
[81] |
YueX, ZhangF, WuH, MingJ, FanZ, ZuoB. A novel route to prepare dry-spun silk fibers from CaCl2–formic acid solution. Mater Lett. 2014;128:175-178.
CrossRef
Google scholar
|
[82] |
OhzawaY, NaganoY, MatsuoT. Studies on dry spinning. I. Fundamental equations. J Appl Polym Sci. 1969;13(2):257-283.
CrossRef
Google scholar
|
[83] |
WeiW, ZhangY, ZhaoY, Luo J, ShaoH, HuX. Bio-inspired capillary dry spinning of regenerated silk fibroin aqueous solution. Mater Sci Eng: C. 2011;31(7):1602-1608.
CrossRef
Google scholar
|
[84] |
ChaochaiT, ImaiY, FuruikeT, Tamura H. Preparation and properties of gelatin fibers fabricated by dry spinning. Fibers. 2016;4(1):2.
CrossRef
Google scholar
|
[85] |
LuL, FanS, NiuQ, et al. Strong silk fibers containing cellulose nanofibers generated by a bioinspired microfluidic chip. ACS Sustain Chem Eng. 2019;7(17):14765-14774.
CrossRef
Google scholar
|
[86] |
FuC, ShaoZ, FritzV. Animal silks: their structures, properties and artificial production. Chem Commun. 2009;(43):6515-6529.
CrossRef
Google scholar
|
[87] |
KarakeçiliA, Topuz B, KorpayevS, ErdekM. Metal-organic frameworks for on-demand pH controlled delivery of vancomycin from chitosan scaffolds. Mater Sci Eng: C. 2019;105:110098.
CrossRef
Google scholar
|
[88] |
ChenS, HuangT, ZuoH, et al. A single integrated 3d-printing process customizes elastic and sustainable triboelectric nanogenerators for wearable electronics. Adv Funct Mater. 2018;28(46):1805108.
CrossRef
Google scholar
|
[89] |
ZarekM, LayaniM, CoopersteinI, SachyaniE, CohnD, MagdassiS. 3D printing:3D printing of shape memory polymers for flexible electronic devices (Adv. Mater. 22/2016). Adv Mater. 2016;28(22):4166
CrossRef
Google scholar
|
[90] |
BracciniS, ChenC-B, ŁucejkoJJ, et al. Additive manufacturing of wet-spun chitosan/hyaluronic acid scaffolds for biomedical applications. Carbohydr Polymers. 2024;329(13):121788.
CrossRef
Google scholar
|
[91] |
ZhangM, ZhaoM, JianM, et al. Printable smart pattern for multifunctional energy-management E-textile. Matter. 2019;1(1):168-179.
CrossRef
Google scholar
|
[92] |
MercaderC, LucasA, DerréA, et al. Kinetics of fiber solidification. Proc Natl Acad Sci. 2010;107(43):18331-18335.
CrossRef
Google scholar
|
[93] |
RenN, ChenS, CuiM, et al. Ultrastrong and flame-retardant microfibers via microfluidic wet spinning of phosphorylated cellulose nanofibrils. Carbohydr Polymers. 2022;296:119945.
CrossRef
Google scholar
|
[94] |
KongL, JinX, HuD, FengL, ChenD, Li H. Functional delivery vehicle of organic nanoparticles in inorganic crystals. Chin Chem Lett. 2019;30(12):2351-2354.
CrossRef
Google scholar
|
[95] |
KinahanME, Filippidi E, KösterS, et al. Tunable silk: using microfluidics to fabricate silk fibers with controllable properties. Biomacromolecules. 2011;12(5):1504-1511.
CrossRef
Google scholar
|
[96] |
LiD, Jacobsen MM, Gyune RimN, BackmanD, KaplanDL, WongJY. Introducing biomimetic shear and ion gradients to microfluidic spinning improves silk fiber strength. Biofabrication. 2017;9(2):025025.
CrossRef
Google scholar
|
[97] |
YuY, ShangL, GuoJ, WangJ, ZhaoY. Design of capillary microfluidics for spinning cell-laden microfibers. Nat Protoc. 2018;13(11):2557-2579.
CrossRef
Google scholar
|
[98] |
DuX-Y, LiQ, WuG, ChenS. Multifunctional micro/nanoscale fibers based on microfluidic spinning technology. Adv Mater. 2019;31(52):1903733.
CrossRef
Google scholar
|
[99] |
CuiQ, BellDJ, RauerSB, Wessling M. Wet-spinning of biocompatible core–shell polyelectrolyte complex fibers for tissue engineering. Adv Mater Interfaces. 2020;7(23):2000849.
CrossRef
Google scholar
|
[100] |
WeiD, SunJ, BoldersonJ, et al. Continuous fabrication and assembly of spatial cell-laden fibers for a tissue-Like construct via a photolithographic-based microfluidic chip. ACS Appl Mater Interfaces. 2017;9(17):14606-14617.
CrossRef
Google scholar
|
[101] |
Song,Y, YuXQ, ChenS. Recent advances in microfluidic fiber-spinning chemistry. J Polym Sci. 2024;62(3):447-462.
CrossRef
Google scholar
|
[102] |
LiY, LiJ, SunJ, et al. Bioinspired and mechanically strong fibers based on engineered non-spider chimeric proteins. Angew Chem Int Ed. 2020;59(21):8148-8152.
CrossRef
Google scholar
|
[103] |
SuJ, ZhaoK, RenY, et al. Biosynthetic structural proteins with super plasticity, extraordinary mechanical performance, biodegradability, biocompatibility and information storage ability. Angew Chem Int Ed. 2022;61(12):e202117538.
CrossRef
Google scholar
|
[104] |
SunJ, LiB, WangF, et al. Proteinaceous fibers with outstanding mechanical properties manipulated by supramolecular interactions. CCS Chemistry. 2021;3(6):1669-1677.
CrossRef
Google scholar
|
[105] |
OksmanK, MathewAP, LångströmR, NyströmB, JosephK. The influence of fibre microstructure on fibre breakage and mechanical properties of natural fibre reinforced polypropylene. Compos Sci Technol. 2009;69(11-12):1847-1853.
CrossRef
Google scholar
|
[106] |
WuY, ZhangY, WuH, et al. Solvent-exchange-assisted wet annealing: a new strategy for superstrong, tough, stretchable, and anti-fatigue hydrogels. Adv Mater. 2023;35(15):2210624.
CrossRef
Google scholar
|
[107] |
LuL, FanS, GengL, Yao X, ZhangY. Low-loss light-guiding, strong silk generated by a bioinspired microfluidic chip. Chem Eng J. 2021;405:126793.
CrossRef
Google scholar
|
[108] |
LiY, MengQ, ChenS, et al. Advances, challenges, and prospects for surgical suture materials. Acta Biomater. 2023;168:78-112.
CrossRef
Google scholar
|
[109] |
PengX, LiuG, ZhuL, YuK, QianK, Zhan X. In vitro and in vivo study of novel antimicrobial gellan-polylysine polyion complex fibers as suture materials. Carbohydr Res. 2020;496:108115.
CrossRef
Google scholar
|
[110] |
WangQ, ZhangS, JiangJ, et al. Electrospun radially oriented berberine-PHBV nanofiber dressing patches for accelerating diabetic wound healing. Regen Biomater. 2024;11:rbae063.
CrossRef
Google scholar
|
[111] |
YaoS, XieZ, YeL, et al. Ultrasmall sized calcium phosphate nanoclusters based organic-inorganic biofiber for accelerated bone fracture healing. Mater Today Nano. 2023;21:100290.
CrossRef
Google scholar
|
[112] |
CaoX, YeC, CaoL, ShanY, RenJ, LingS. Biomimetic spun silk ionotronic fibers for intelligent discrimination of motions and tactile stimuli. Adv Mater. 2023;35(36):2300447.
CrossRef
Google scholar
|
/
〈 |
|
〉 |