Mitochondrial fission factor: a living way for mitochondria sensing food

Mengmeng Zhi , Rong Cao , Xianghui Fu , Ling Li

MedComm ›› 2024, Vol. 5 ›› Issue (10) : e770

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MedComm ›› 2024, Vol. 5 ›› Issue (10) : e770 DOI: 10.1002/mco2.770
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Mitochondrial fission factor: a living way for mitochondria sensing food

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Mengmeng Zhi, Rong Cao, Xianghui Fu, Ling Li. Mitochondrial fission factor: a living way for mitochondria sensing food. MedComm, 2024, 5(10): e770 DOI:10.1002/mco2.770

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References

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Henschke S, Nolte H, Magoley J, et al. Food perception promotes phosphorylation of MFFS131 and mitochondrial fragmentation in liver. Science. 2024; 384(6694): 438-446.

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Hammerschmidt P, Ostkotte D, Nolte H, et al. CerS6-derived sphingolipids interact with Mff and promote mitochondrial fragmentation in obesity. Cell. 2019; 177(6): 1536-1552.e1523.

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Kwon E, Joung HY, Liu SM, Chua SC Jr, Schwartz GJ, Jo YH. Optogenetic stimulation of the liver-projecting melanocortinergic pathway promotes hepatic glucose production. Nat Commun. 2020; 11(1): 6295.

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Brandt C, Nolte H, Henschke S, et al. Food perception primes hepatic ER homeostasis via melanocortin-dependent control of mTOR activation. Cell. 2018; 175(5): 1321-1335.e1320.

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Kraus F, Roy K, Pucadyil TJ, Ryan MT. Function and regulation of the divisome for mitochondrial fission. Nature. 2021; 590(7844): 57-66.

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2024 The Author(s). MedComm published by Sichuan International Medical Exchange & Promotion Association (SCIMEA) and John Wiley & Sons Australia, Ltd.

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