Tumor cells utilize acetate for tumor growth and immune evasion

Peng Sun; Juanjuan Liu; Deliang Guo

doi:10.1002/mco2.717

MedComm ›› 2024, Vol. 5 ›› Issue (9) : e717 DOI: 10.1002/mco2.717

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Tumor cells utilize acetate for tumor growth and immune evasion

Peng Sun ¹^,^†
, Juanjuan Liu ¹
, Deliang Guo ²^,^†

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Peng Sun, Juanjuan Liu, Deliang Guo. Tumor cells utilize acetate for tumor growth and immune evasion. MedComm, 2024, 5(9): e717 DOI:10.1002/mco2.717

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References

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[1]	Wang J, Yang Y, Shao F, et al. Acetate reprogrammes tumour metabolism and promotes PD-L1 expression and immune evasion by upregulating c-Myc. Nat Metab. 2024; 6(5): 914-932.

[2]	Cheng C, Ru P, Geng F, et al. Glucose-mediated N-glycosylation of SCAP is essential for SREBP-1 activation and tumor growth. Cancer Cell. 2015; 28(5): 569-581.

[3]	Guo D. SCAP links glucose to lipid metabolism in cancer cells. Mol Cell Oncol. 2016; 3(2): e1132120.

[4]	Bian X, Jiang H, Meng Y, Li YP, Fang J, Lu Z, Regulation of gene expression by glycolytic and gluconeogenic enzymes. Trends Cell Biol. 2022; 32(9): 786-799.

[5]	Cheng C, Geng F, Cheng X, Guo D. Lipid metabolism reprogramming and its potential targets in cancer. Cancer Commun. 2018; 38(1): 27.

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2024 The Author(s). MedComm published by Sichuan International Medical Exchange & Promotion Association (SCIMEA) and John Wiley & Sons Australia, Ltd.