Key Roles in the Process of Extravasation and Colonization: Acyl-coenzyme A Synthetase Long-chain Family Member 4 and Polyunsaturated Lipids

Jiayu Han; Jie Zhang; Yicheng Chen

doi:10.1002/mco2.70264

MedComm ›› 2025, Vol. 6 ›› Issue (7) : e70264 DOI: 10.1002/mco2.70264

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Key Roles in the Process of Extravasation and Colonization: Acyl-coenzyme A Synthetase Long-chain Family Member 4 and Polyunsaturated Lipids

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Jiayu Han, Jie Zhang, Yicheng Chen. Key Roles in the Process of Extravasation and Colonization: Acyl-coenzyme A Synthetase Long-chain Family Member 4 and Polyunsaturated Lipids. MedComm, 2025, 6(7): e70264 DOI:10.1002/mco2.70264

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References

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[1]	Y. Wang, M. Hu, J. Cao, et al., “ACSL4 and Polyunsaturated Lipids Support Metastatic Extravasation and Colonization,” Cell 188, no. 2 (2025): 412-429.

[2]	S. Gerstberger, Q. Jiang, and G. K., “Metastasis,” Cell 186, no. 8 (2023): 1564-1579.

[3]	I. Elia, G. Doglioni, and S. M. Fendt, “Metabolic Hallmarks of Metastasis Formation,” Trends in Cell Biology 28, no. 8 (2018): 673-684.

[4]	X. Jiang, B. R. Stockwell, and M. Conrad, “Ferroptosis: Mechanisms, Biology and Role in Disease,” Nature Reviews Molecular Cell Biology 22, no. 4 (2021): 266-282.

[5]	S. Chen, N. E. Sanjana, K. Zheng, et al., “Genome-Wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis,” Cell 160, no. 6 (2015): 1246-1260.

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