New Insights Into the Human Dopamine Transporter: Structure, Function, and Therapeutic Potential

Qi Weng; Qi Wu; Quan Zheng

doi:10.1002/mco2.70187

MedComm ›› 2025, Vol. 6 ›› Issue (5) : e70187 DOI: 10.1002/mco2.70187

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New Insights Into the Human Dopamine Transporter: Structure, Function, and Therapeutic Potential

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Qi Weng, Qi Wu, Quan Zheng. New Insights Into the Human Dopamine Transporter: Structure, Function, and Therapeutic Potential. MedComm, 2025, 6(5): e70187 DOI:10.1002/mco2.70187

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References

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[1]	Y. Li, X. Wang, Y. Meng, et al., “Dopamine Reuptake and Inhibitory Mechanisms in Human Dopamine Transporter,” Nature 632 (2024): 686-694.

[2]	D. K. Srivastava, V. Navratna, D. K. Tosh, et al., “Structure of the Human Dopamine Transporter and Mechanisms of Inhibition,” Nature 632 (2024): 672-677.

[3]	J. C. Nielsen, K. Salomon, I. E. Kalenderoglou, et al., “Structure of the Human Dopamine Transporter in Complex With Cocaine,” Nature 632 (2024): 678-685.

[4]	B. Channer, S. M. Matt, E. A. Nickoloff-Bybel, et al., “Dopamine, Immunity, and Disease,” Pharmacological Reviews 75, no. 1 (2023): 62-158.

[5]	M. E. A. Reith, S. Kortagere, C. E. Wiers, et al., “The Dopamine Transporter Gene SLC6A3: Multidisease Risks,” Molecular Psychiatry 27, no. 2 (2022): 1031-1046.

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