Time – The fourth dimension of immune cells

Guiming Li; Wenjun Zhang; Jing Yang

doi:10.1002/mco2.682

MedComm ›› 2024, Vol. 5 ›› Issue (8) : e682 DOI: 10.1002/mco2.682

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Time – The fourth dimension of immune cells

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CAR-T therapy / drug discovery / immunotherapy

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Guiming Li, Wenjun Zhang, Jing Yang. Time – The fourth dimension of immune cells. MedComm, 2024, 5(8): e682 DOI:10.1002/mco2.682

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References

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[1]	Kirschenbaum D, Xie K, Ingelfinger F, et al. Time-resolved single-cell transcriptomics defines immune trajectories in glioblastoma. Cell. 2024; 187(1): 149-165. e23.

[2]	Dagar G, Gupta A, Masoodi T, et al. Harnessing the potential of CAR-T cell therapy: progress, challenges, and future directions in hematological and solid tumor treatments. J Transl Med. 2023; 21(1): 449.

[3]	Yofe I, Dahan R, Amit I. Single-cell genomic approaches for developing the next generation of immunotherapies. Nat Med. 2020; 26(2): 171-177.

[4]	Vasan N, Baselga J, Hyman DM. A view on drug resistance in cancer. Nature. 2019; 575(7782): 299-309.

[5]	Falcomata C, Baerthel S, Widholz SA, et al. Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment. Nat Cancer. 2022; 3(3): 318-336.

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2024 The Author(s). MedComm published by Sichuan International Medical Exchange & Promotion Association (SCIMEA) and John Wiley & Sons Australia, Ltd.