SARS-CoV-2 Omicron subvariants from BA.2 to BA.2.86 and JN.1: strong lung infection ability and evolving immune escape capacity

Bixia Hong1, Maochen Li1, Huahao Fan1,2,3()

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MedComm ›› 2024, Vol. 5 ›› Issue (7) : e578. DOI: 10.1002/mco2.578
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SARS-CoV-2 Omicron subvariants from BA.2 to BA.2.86 and JN.1: strong lung infection ability and evolving immune escape capacity

  • Bixia Hong1, Maochen Li1, Huahao Fan1,2,3()
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Bixia Hong, Maochen Li, Huahao Fan. SARS-CoV-2 Omicron subvariants from BA.2 to BA.2.86 and JN.1: strong lung infection ability and evolving immune escape capacity. MedComm, 2024, 5(7): e578 https://doi.org/10.1002/mco2.578

References

1 P Qu, K Xu, JN Faraone, et al. Immune evasion, infectivity, and fusogenicity of SARS-CoV-2 BA.2.86 and FLip variants. Cell. 2024;187(3):585-595. e6.
2 L Zhang, A Kempf, I Nehlmeier, et al. SARS-CoV-2 BA.2.86 enters lung cells and evades neutralizing antibodies with high efficiency. Cell. 2024;187(3):596-608. e17.
3 Q Wang, Y Guo, L Liu, et al. Antigenicity and receptor affinity of SARS-CoV-2 BA.2.86 spike. Nature. 2023;624(7992):639-644.
4 S Yang, Y Yu, Y Xu, et al. Fast evolution of SARS-CoV-2 BA.2.86 to JN.1 under heavy immune pressure. Lancet Infect Dis. 2024;24(2):e70-e72.
5 PV Markov, M Ghafari, M Beer, et al. The evolution of SARS-CoV-2. Nat Rev Microbiol. 2023;21(6):361-379.
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