Neoadjuvant immunotherapy: new horizon for lymph node preservation

Nian-Nian Zhong1, Bing Liu1,2(), Lin-Lin Bu1,2()

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MedComm ›› 2024, Vol. 5 ›› Issue (5) : e577. DOI: 10.1002/mco2.577
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Neoadjuvant immunotherapy: new horizon for lymph node preservation

  • Nian-Nian Zhong1, Bing Liu1,2(), Lin-Lin Bu1,2()
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Keywords

cancer treatment / immunotherapy / lymph node / organ preservation / T cell / treatment de-escalation

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Nian-Nian Zhong, Bing Liu, Lin-Lin Bu. Neoadjuvant immunotherapy: new horizon for lymph node preservation. MedComm, 2024, 5(5): e577 https://doi.org/10.1002/mco2.577

References

1 MK Rahim, TLH Okholm, KB Jones, et al. Dynamic CD8(+) T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted in metastatic lymph nodes. Cell. 2023;186(6):1127-1143. .e18.
2 LM Cao, NN Zhong, ZZ Li, et al. Lymph node metastasis in oral squamous cell carcinoma: where we are and where we are going. Clin Transl Discov. 2023;3(4):e227.
3 AM Luoma, S Suo, Y Wang, et al. Tissue-resident memory and circulating T cells are early responders to pre-surgical cancer immunotherapy. Cell. 2022;185(16):2918-2935.e29.
4 MH Spitzer, Y Carmi, NE Reticker-Flynn, et al. Systemic immunity is required for effective cancer immunotherapy. Cell. 2017;168(3):487-502. .e15.
5 LM Cao, NN Zhong, B Liu, et al. A surge of hope: a case of lymph node hyperplasia after oral squamous cell carcinoma neoadjuvant immunotherapy. Oral Oncol. 2023;147:106613.
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