Interplay of IL-17A/IL-17RA signaling with microbial homeostasis in systemic anti-tumoral responses

Shi-jun He1,2, Jian-ping Zuo1,3(), Ze-min Lin1,3()

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MedComm ›› 2024, Vol. 5 ›› Issue (4) : e524. DOI: 10.1002/mco2.524
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Interplay of IL-17A/IL-17RA signaling with microbial homeostasis in systemic anti-tumoral responses

  • Shi-jun He1,2, Jian-ping Zuo1,3(), Ze-min Lin1,3()
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Shi-jun He, Jian-ping Zuo, Ze-min Lin. Interplay of IL-17A/IL-17RA signaling with microbial homeostasis in systemic anti-tumoral responses. MedComm, 2024, 5(4): e524 https://doi.org/10.1002/mco2.524

References

1 V Chandra, L Li, O Le Roux, et al. Gut epithelial Interleukin-17 receptor A signaling can modulate distant tumors growth through microbial regulation. Cancer Cell. 2024;42(1):85-100.e6.
2 Q Luo, Y Liu, K Shi, et al. An autonomous activation of interleukin-17 receptor signaling sustains inflammation and promotes disease progression. Immunity. 2023;56(9):2006-2020.e6.
3 KHG Mills. IL-17 and IL-17-producing cells in protection versus pathology. Nat Rev Immunol. 2023;23(1):38-54.
4 G El Tekle, WS Garrett. Bacteria in cancer initiation, promotion and progression. Nat Rev Cancer. 2023;23(9):600-618.
5 S-J He, H-H Ding, L Chen, et al. Repression of interferon regulatory factor-4 (IRF4) hyperactivation restricts murine lupus. Signal Transduct Target Ther. 2023;8(1):188.
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