Postoperative concurrent chemoradiotherapy utilizing intensity-modulated radiation therapy (IMRT) for a young adult male with primary tracheal carcinoma: A case report demonstrating 5-year long-term survival

Abstract

Objective: The incidence of primary tracheal neoplasm is extremely rare. Squamous cell carcinoma (SCC) is the most prevalent histological type of tracheal malignancy. Postoperative adjuvant radiotherapy can be considered as a curative management option. However, there are limited data available on the use of radiotherapy or concurrent chemoradiotherapy for tracheal cancer, particularly intensity-modulated radiotherapy.

Patient and methods: Herein, we present a case report of a young adult male diagnosed with primary SCC of the trachea who underwent postoperative concurrent chemoradiotherapy utilizing intensity-modulated radiation therapy (IMRT). The treatment included 50.4 Gy radiation in 28 fractions and two cycles of chemotherapy.

Results: The patient experienced grade Ⅰ dermatitis and grade Ⅱ granulocytosis. Follow-up showed no evidence of recurrence or significant adverse effects. The patient achieved 5-year long-term survival with good quality of life.

Conclusion: Postoperative concurrent chemoradiotherapy using IMRT is effective for primary tracheal carcinoma, offering long-term survival and quality of life benefits.

Keywords

tracheal squamous cell carcinoma (SCC) / postoperative concurrent chemoradiotherapy / intensity-modulated radiation therapy (IMRT)

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The Author(s). Malignancy Spectrum published by John Wiley & Sons Australia, Ltd on behalf of Higher Education Press.