Author's contributions
Hanyang Liu: Writing - review & editing, Writing - original draft, Supervision, Project administration, Investigation, Funding acquisition, Conceptualization.
Declaration of competing interest
The author received a visiting fellow scholar at the National Institutes of Health (NIH), USA. However, this work was done by the author independently without any resources from NIH, thereby not reflecting the views of the NIH or the U.S. Department of Health and Human Services. The author declares that there is no conflicts of interest.
Acknowledgements
This work was funded by National Natural Science Foundation of China (82300730) and Changzhou Science and Technology Bu-reau of China (CJ20241116). The author thanks the professional advice and academic transitioning support from Prof. Frank Tacke's and Dr. Adrien Guillot's Labs, in the Department of Hep-atology and Gastroenterology, Charité Universit € atsmedizin Berlin, Germany.