Integrating GLP-1 receptor agonists with anti-amyloid immunotherapy for Alzheimer's disease: a phased clinical roadmap

Junzhe Huang , Shengya Wang , Vincent C. T. Mok , Weihong Song , Ho Ko , Yun Zhang

Life Medicine ›› 2025, Vol. 4 ›› Issue (6) : lnaf036

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Life Medicine ›› 2025, Vol. 4 ›› Issue (6) :lnaf036 DOI: 10.1093/lifemedi/lnaf036
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Integrating GLP-1 receptor agonists with anti-amyloid immunotherapy for Alzheimer's disease: a phased clinical roadmap
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Junzhe Huang, Shengya Wang, Vincent C. T. Mok, Weihong Song, Ho Ko, Yun Zhang. Integrating GLP-1 receptor agonists with anti-amyloid immunotherapy for Alzheimer's disease: a phased clinical roadmap. Life Medicine, 2025, 4(6): lnaf036 DOI:10.1093/lifemedi/lnaf036

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Cummings JL , Atri A , Feldman HH et al. Evoke and evoke+: design of two large-scale, double-blind, placebo-controlled, phase 3 studies evaluating efficacy, safety, and tolerability of semaglutide in early-stage symptomatic Alzheimer's disease. Alzheimers Res Ther 2025; 17: 14.

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