mRNA therapy: a precise and efficient approach for disease treatment

Jia-Yi Zhou , Ying Yang

Life Medicine ›› 2024, Vol. 3 ›› Issue (4) : lnae035

PDF (393KB)
Life Medicine ›› 2024, Vol. 3 ›› Issue (4) : lnae035 DOI: 10.1093/lifemedi/lnae035
News & Opinions

mRNA therapy: a precise and efficient approach for disease treatment

Author information +
History +
PDF (393KB)

Cite this article

Download citation ▾
Jia-Yi Zhou, Ying Yang. mRNA therapy: a precise and efficient approach for disease treatment. Life Medicine, 2024, 3(4): lnae035 DOI:10.1093/lifemedi/lnae035

登录浏览全文

4963

注册一个新账户 忘记密码

References

[1]

Wolff JA , Malone RW , Williams P , et al. Direct gene transfer into mouse muscle in vivo. Science 1990; 247: 1465- 68.

[2]

Zhang G , Tang T , Chen Y , et al. mRNA vaccines in disease prevention and treatment. Signal Transduct Target Ther 2023; 8: 365.

[3]

Koeberl D , Schulze A , Sondheimer N , et al. Interim analyses of a first-in-human phase 1/2 mRNA trial for propionic acidaemia. Nature 2024; 628: 872- 7.

[4]

Jiang L , Park J-S , Yin L , et al. Dual mRNA therapy restores metabolic function in long-term studies in mice with propionic acidemia. Nat Commun 2020; 11: 5339.

[5]

Burris HA , Patel MR , Cho DC , et al. A phase I multicenter study to assess the safety, tolerability, and immunogenicity of mRNA-4157 alone in patients with resected solid tumors and in combination with pembrolizumab in patients with unresectable solid tumors. J Clin Oncol 2019; 37: 2523.

RIGHTS & PERMISSIONS

The Author(s). Published by Oxford University Press on behalf of Higher Education Press.

AI Summary AI Mindmap
PDF (393KB)

315

Accesses

0

Citation

Detail

Sections
Recommended

AI思维导图

/