Deciphering microbiota-host interplay: bacterial metabolites and protein post-translational modifications

Mingya Zhang , Sangkyu Lee , Min Huang , Minjia Tan

Life Medicine ›› 2024, Vol. 3 ›› Issue (1) : lnae003

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Life Medicine ›› 2024, Vol. 3 ›› Issue (1) : lnae003 DOI: 10.1093/lifemedi/lnae003
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Deciphering microbiota-host interplay: bacterial metabolites and protein post-translational modifications

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Mingya Zhang, Sangkyu Lee, Min Huang, Minjia Tan. Deciphering microbiota-host interplay: bacterial metabolites and protein post-translational modifications. Life Medicine, 2024, 3(1): lnae003 DOI:10.1093/lifemedi/lnae003

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Zhai Y, Chen L, Zhao Q, et al. Cysteine carboxyethylation generates neoantigens to induce HLA-restricted autoimmunity. Science 2023;379:eabg2482.

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Pietrocola F, Galluzzi L, Bravo-San Pedro JM, et al. Acetyl coenzyme a: a central metabolite and second messenger. Cell Metab 2015;21:805–21.

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O’Keefe SJ. Diet, microorganisms and their metabolites, and colon cancer. Nat Rev Gastroenterol Hepatol 2016;13:691–706.

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Fellows R, Denizot J, Stellato C, et al. Microbiota derived short chain fatty acids promote histone crotonylation in the colon through histone deacetylases. Nat Commun 2018;9:105.

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