Mutations in TUBA4A lead to human zygotic arrest and early developmental failure

Lin Li , Linfan Mao , Zhiguo Zhang , Yiying Yu , Miaohui Ding , Yongyan Zhi , Yunxia Cao , Beili Chen , Jie Na

Life Medicine ›› 2023, Vol. 2 ›› Issue (5) : 9

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Life Medicine ›› 2023, Vol. 2 ›› Issue (5) : 9 DOI: 10.1093/lifemedi/lnad032
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Mutations in TUBA4A lead to human zygotic arrest and early developmental failure

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Lin Li, Linfan Mao, Zhiguo Zhang, Yiying Yu, Miaohui Ding, Yongyan Zhi, Yunxia Cao, Beili Chen, Jie Na. Mutations in TUBA4A lead to human zygotic arrest and early developmental failure. Life Medicine, 2023, 2(5): 9 DOI:10.1093/lifemedi/lnad032

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References

[1]

Chen B, Guo J, Wang T, et al. Maternal heterozygous mutation in CHEK1 leads to mitotic arrest in human zygotes. Protein Cell 2022;13:148–54.

[2]

Sang Q, Ray PF, Wang L. Understanding the genetics of human infertility. Science 2023;380:158–63.

[3]

Sui H, Downing KH. Structural basis of interprotofilament interaction and lateral deformation of microtubules. Structure 2010;18:1022–31.

[4]

Hu W, Zeng H, Shi Y, et al. Single-cell transcriptome and translatome dual-omics reveals potential mechanisms of human oocyte maturation. Nat Commun 2022;13:5114.

[5]

Zou Z, Zhang C, Wang Q, et al. Translatome and transcriptome co-profiling reveals a role of TPRXs in human zygotic genome activation. Science 2022;378:abo7923.

[6]

Feng R, Sang Q, Kuang Y, et al. Mutations in TUBB8 and human oocyte meiotic arrest. N Engl J Med 2016;374:223–32.

[7]

Wu T, Dong J, Fu J, et al. The mechanism of acentrosomal spindle assembly in human oocytes. Science 2022;378:eabq7361.

[8]

Li Q, Zhao L, Zeng Y, et al. Large-scale analysis of de novo mutations identifies risk genes for female infertility characterized by oocyte and early embryo defects. Genome Biol 2023;24:68.

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The Author(s) 2023. Published by Oxford University Press on behalf of Higher Education Press.

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