Brain assembloid: a human model for neural circuits research

Shanshan Wu , Da Wang , Yan Liu

Life Medicine ›› 2023, Vol. 2 ›› Issue (5) : 1

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Life Medicine ›› 2023, Vol. 2 ›› Issue (5) : 1 DOI: 10.1093/lifemedi/lnad031
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Brain assembloid: a human model for neural circuits research

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Shanshan Wu, Da Wang, Yan Liu. Brain assembloid: a human model for neural circuits research. Life Medicine, 2023, 2(5): 1 DOI:10.1093/lifemedi/lnad031

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BireyF, Andersen J, MakinsonCD, et al. Assembly of functionally integrated human forebrain spheroids. Nature 2017;545:54–9.

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PaşcaSP, Arlotta P, BateupHS, et al. A nomenclature consensus for nervous system organoids and assembloids. Nature 2022;609:907–10.

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XiangY, TanakaY, CakirB, et al. hESC-derived thalamic organoids form reciprocal projections when fused with cortical organoids. Cell Stem Cell 2019;24:487–497.e7.

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BireyF, LiM-Y, GordonA, et al. Dissecting the molecular basis of human interneuron migration in forebrain assembloids from Timothy syndrome. Cell Stem Cell 2022;29:248–264.e7.

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AndersenJ, RevahO, MiuraY, et al. Generation of functional human 3D cortico-motor assembloids. Cell 2020;183:1913–1929.e26.

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