Novel single-cell mtDNA sequencing technology reveals hidden mutations in oocytes, blastoids, and stem cells

Ismail M. Shakir, Mo Li

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Life Medicine ›› 2023, Vol. 2 ›› Issue (4) : 1. DOI: 10.1093/lifemedi/lnad028
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Novel single-cell mtDNA sequencing technology reveals hidden mutations in oocytes, blastoids, and stem cells

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Ismail M. Shakir, Mo Li. Novel single-cell mtDNA sequencing technology reveals hidden mutations in oocytes, blastoids, and stem cells. Life Medicine, 2023, 2(4): 1 https://doi.org/10.1093/lifemedi/lnad028

References

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Bi C, Wang L, Fan Y, et al. Single-cell individual full-length mtDNA sequencing by iMiGseq uncovers unexpected heteroplasmy shifts in mtDNA editing. Nucleic Acids Res 2023;51:e48.
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Bi C, Wang L, Fan Y, et al. Quantitative haplotype-resolved analysis of mitochondrial DNA heteroplasmy in human single oocytes, blastoids, and pluripotent stem cells. Nucleic Acids Res 2023;51:3793–805.
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2023 The Author(s) 2023. Published by Oxford University Press on behalf of Higher Education Press.
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