Mosaic somatic HRAS mutation causes unilateral psoriasis

References

[1] Griffiths CEM, Armstrong AW, Gudjonsson JE, et al. Psoriasis. Lancet 2021;397:1301–15.

[2] Lin P, Baldassare JJ, Voorhees JJ, et al. Increased activation of Ras in psoriatic lesions. Skin Pharmacol Appl Skin Physiol 1999;12:90–7.

[3] Yu Z, Gong Y, Cui L, et al. High-throughput transcriptome and pathogenesis analysis of clinical psoriasis. J Dermatol Sci 2020;98:109–18.

[4] Murugan AK, Grieco M, Tsuchida N. RAS mutations in human cancers: roles in precision medicine. Semin Cancer Biol 2019;59:23–35.

[5] Denayer E, Parret A, Chmara M, et al. Mutation analysis in Costello syndrome: functional and structural characterization of the HRAS p.Lys117Arg mutation. Hum Mutat 2008;29:232–9.

[6] Groesser L, Herschberger E, Ruetten A, et al. Postzygotic HRAS and KRAS mutations cause nevus sebaceous and Schimmelpenning syndrome. Nat Genet 2012;44:783–7.

[7] Hafner C, Toll A, Gantner S, et al. Keratinocytic epidermal nevi are associated with mosaic RAS mutations. J Med Genet 2012;49:249–53.

[8] Gunderson AJ, Mohammed J, Horvath FJ, et al. CD8(+) T cells mediate RAS-induced psoriasis-like skin inflammation through IFN-γ. J Invest Dermatol 2013;133:955–63.

[9] Tarutani M, Imai Y, Yasuda K, et al. Neutrophil-dominant psoriasis-like skin inflammation induced by epidermal-specific expression of Raf in mice. J Dermatol Sci 2010;58:28–35.

[10] Wang S, Zhang Z, Peng H, et al. Recent advances on the roles of epidermal growth factor receptor in psoriasis. Am J Transl Res 2019;11:520–8.

RIGHTS & PERMISSIONS

2023 The Author(s) 2023. Published by Oxford University Press on behalf of Higher Education Press.