Human platelet lysate as a substitute for serum in natural killer cell generation and expansion

Chao Li , Hao Zhu , Lei Zhang , Xianwei Liu , Yibing Ji , Haihong Zhang , Zhongpeng Li , Chen Wu , Fangfang Zhu

Life Medicine ›› 2023, Vol. 2 ›› Issue (2) : 10

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Life Medicine ›› 2023, Vol. 2 ›› Issue (2) : 10 DOI: 10.1093/lifemedi/lnad011
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Human platelet lysate as a substitute for serum in natural killer cell generation and expansion

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Chao Li, Hao Zhu, Lei Zhang, Xianwei Liu, Yibing Ji, Haihong Zhang, Zhongpeng Li, Chen Wu, Fangfang Zhu. Human platelet lysate as a substitute for serum in natural killer cell generation and expansion. Life Medicine, 2023, 2(2): 10 DOI:10.1093/lifemedi/lnad011

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References

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Wu SY, Fu T, Jiang YZ, et al. Natural killer cells in cancer biology and therapy. Mol Cancer 2020;19:120.

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Dolstra H, Roeven MWH, Spanholtz J, et al. Successful transfer of umbilical cord blood CD34(+) hematopoietic stem and progenitor-derived NK cells in older acute myeloid leukemia patients. Clin Cancer Res 2017;23:4107–18.

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Bieback K, Hecker A, Kocaomer A, et al. Human alternatives to fetal bovine serum for the expansion of mesenchymal stromal cells from bone marrow. Stem Cells 2009;27:2331–41.

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Trebeden-Negre H, Vieillard V, Rosenzwajg M, et al. Polyvalent immunoglobulins, platelet lysate and lenalidomide: cocktail for polyfunctional NK cells expansion for multiple myeloma. Bone Marrow Transplant 2017;52:480–3.

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Johnson CDL, Zale NE, Frary ED, et al. Feeder-cell-free and serumfree expansion of natural killer cells using cloudz microspheres, G-Rex6M, and human platelet lysate. Front Immunol 2022;13:803380.

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The Author(s) 2023. Published by Oxford University Press on behalf of Higher Education Press.

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