Hypothalamic–pituitary–bone marrow axis promotes tumor-induced immunosuppression

Yueli Xu, Jiaxian Yan, Rongbin Zhou

PDF(186 KB)
PDF(186 KB)
Life Medicine ›› 2023, Vol. 2 ›› Issue (1) : 4. DOI: 10.1093/lifemedi/lnac058
Research Highlight
Research Highlight

Hypothalamic–pituitary–bone marrow axis promotes tumor-induced immunosuppression

Author information +
History +

Cite this article

Download citation ▾
Yueli Xu, Jiaxian Yan, Rongbin Zhou. Hypothalamic–pituitary–bone marrow axis promotes tumor-induced immunosuppression. Life Medicine, 2023, 2(1): 4 https://doi.org/10.1093/lifemedi/lnac058

References

[1]
Wang H, Zheng Q, Lu Z, et al. Role of the nervous system in cancers: a review. Cell Death Discov 2021;7:76.
CrossRef Google scholar
[2]
Jiang X, Wang J, Deng X, et al. Role of the tumor microenvironment in PD-L1/PD-1-mediated tumor immune escape. Mol Cancer 2019;18:10.
CrossRef Google scholar
[3]
Yang H, Xia L, Chen J, et al. Stress-glucocorticoid-TSC22D3 axis compromises therapy-induced antitumor immunity. Nat Med 2019;25:1428–41.
CrossRef Google scholar
[4]
Chakraborty B, Byemerwa J, Shepherd J, et al. Inhibition of estrogen signaling in myeloid cells increases tumor immunity in melanoma. J Clin Invest 2021;131:e151347.
CrossRef Google scholar
[5]
Hong JY, Lim J, Carvalho F, et al. Long-term programming of CD8 T cell immunity by perinatal exposure to glucocorticoids. Cell 2020;180:847–61.
CrossRef Google scholar
[6]
Özdemir BC, Dotto GP. Sex hormones and anticancer immunity. Clin Cancer Res 2019;25:4603–10.
CrossRef Google scholar
[7]
Yang C, Jin J, Yang Y, et al. Androgen receptor-mediated CD8(+) T cell stemness programs drive sex differences in antitumor immunity. Immunity 2022;55:1268–83.
CrossRef Google scholar
[8]
Xu Y, Yan J, Tao Y, et al. Pituitary hormone α-MSH promotes tumor-induced myelopoiesis and immunosuppression. Science 2022;377:1085–9–1.
CrossRef Google scholar

RIGHTS & PERMISSIONS

2022 The Author(s) 2022. Published by Oxford University Press on behalf of Higher Education Press.
AI Summary AI Mindmap
PDF(186 KB)

Accesses

Citations

Detail

Sections
Recommended

/