A gas-only bioreactor system maintains stable culture environments and reveals that moderate pH deviations trigger transcriptome-wide responses in human cells cultured in physioxia and physiological buffers

Silvia Arossa , Samhan M. Alsolami , Shannon G. Klein , Yingzi Zhang , Gerardo Ramos-Mandujano , Alexandra Steckbauer , Anieka J. Parry , Juan Carlos Izpisúa-Belmonte , Carlos M. Duarte , Mo Li

Life Medicine ›› 2022, Vol. 1 ›› Issue (2) : 236 -240.

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Life Medicine ›› 2022, Vol. 1 ›› Issue (2) : 236 -240. DOI: 10.1093/lifemedi/lnac056
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A gas-only bioreactor system maintains stable culture environments and reveals that moderate pH deviations trigger transcriptome-wide responses in human cells cultured in physioxia and physiological buffers

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Silvia Arossa, Samhan M. Alsolami, Shannon G. Klein, Yingzi Zhang, Gerardo Ramos-Mandujano, Alexandra Steckbauer, Anieka J. Parry, Juan Carlos Izpisúa-Belmonte, Carlos M. Duarte, Mo Li. A gas-only bioreactor system maintains stable culture environments and reveals that moderate pH deviations trigger transcriptome-wide responses in human cells cultured in physioxia and physiological buffers. Life Medicine, 2022, 1(2): 236-240 DOI:10.1093/lifemedi/lnac056

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The Author(s) 2022. Published by Oxford University Press on behalf of Higher Education Press.

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