Continuous antioxidant drug exposure: a bridge from ideal world to real world of therapy for amyotrophic lateral sclerosis

Jun Wang, Xin-Fu Zhou, Yan-Jiang Wang

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PDF(226 KB)
Life Medicine ›› 2023, Vol. 2 ›› Issue (1) : 1. DOI: 10.1093/lifemedi/lnac042
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Continuous antioxidant drug exposure: a bridge from ideal world to real world of therapy for amyotrophic lateral sclerosis

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Jun Wang, Xin-Fu Zhou, Yan-Jiang Wang. Continuous antioxidant drug exposure: a bridge from ideal world to real world of therapy for amyotrophic lateral sclerosis. Life Medicine, 2023, 2(1): 1 https://doi.org/10.1093/lifemedi/lnac042

References

[1]
Ferrante RJ, Browne SE, Shinobu LA, et al. Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis. J Neurochem. 1997;69:2064–74.
CrossRef Google scholar
[2]
Abe K, Itoyama Y, Sobue G, et al. Confirmatory double-blind, parallel-group, placebo-controlled study of efficacy and safety of edaravone (MCI-186) in amyotrophic lateral sclerosis patients. Amyotroph Lateral Scler Frontotemporal Degener. 2014;15:610–7.
CrossRef Google scholar
[3]
Writing G, Edaravone ALSSG. Safety and efficacy of edaravone in well defined patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial. Lancet Neurol. 2017;16:505–12.
CrossRef Google scholar
[4]
Witzel S, Maier A, Steinbach R, et al. Safety and effectiveness of long-term intravenous administration of edaravone for treatment of patients with amyotrophic lateral sclerosis. JAMA Neurol. 2022;79:121–30.
CrossRef Google scholar
[5]
Jiao SS, Yao XQ, Liu YH, et al. Edaravone alleviates Alzheimer’s disease-type pathologies and cognitive deficits. Proc Natl Acad Sci USA. 2015;112:5225–30.
CrossRef Google scholar

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2022 The Author(s) 2022. Published by Oxford University Press on behalf of Higher Education Press.
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