Sphingolipids mediate lipotoxicity in muscular dystrophies

Yuefan Wang , Ng Shyh-Chang

Life Medicine ›› 2022, Vol. 1 ›› Issue (3) : 273 -275.

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Life Medicine ›› 2022, Vol. 1 ›› Issue (3) : 273 -275. DOI: 10.1093/lifemedi/lnac015
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Sphingolipids mediate lipotoxicity in muscular dystrophies

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Yuefan Wang, Ng Shyh-Chang. Sphingolipids mediate lipotoxicity in muscular dystrophies. Life Medicine, 2022, 1(3): 273-275 DOI:10.1093/lifemedi/lnac015

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Laurila PP, Luan P, Wohlwend M, et al. Inhibition of sphingolipid de novo synthesis counteracts muscular dystrophy. Sci Adv 2022;8:eabh4423.

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Li CW, Yu K, Shyh-Chang N, et al. Pathogenesis of sarcopenia and the relationship with fat mass: descriptive review. J Cachexia Sarcopenia Muscle 2022;13:781–94.

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Chaurasia B, Summers SA. Ceramides in metabolism: key lipotoxic players. Annu Rev Physiol 2021;83:303–30.

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