Local hyperthermia therapy: a novel strategy turning white fat brown

Lingyan Xu, Yu Li, Toren Finkel, Xinran Ma

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PDF(267 KB)
Life Medicine ›› 2022, Vol. 1 ›› Issue (2) : 78-80. DOI: 10.1093/lifemedi/lnac005
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Local hyperthermia therapy: a novel strategy turning white fat brown

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Lingyan Xu, Yu Li, Toren Finkel, Xinran Ma. Local hyperthermia therapy: a novel strategy turning white fat brown. Life Medicine, 2022, 1(2): 78‒80 https://doi.org/10.1093/lifemedi/lnac005

References

[1]
RedmanLM, de Jonge L, FangX, et al. Lack of an effect of a novel beta3-adrenoceptor agonist, TAK-677, on energy metabolism in obese individuals: a double-blind, placebo-controlled randomized study. J Clin Endocrinol Metab 2007;92:527–531
CrossRef Google scholar
[2]
ArcherAE, RogersRS, Von SchulzeAT, et al. Heat shock protein 72 regulates hepatic lipid accumulation. Am J Physiol Regul Integr Comp Physiol 2018;315:R696–R707
CrossRef Google scholar
[3]
HooperPL. Hot-tub therapy for type 2 diabetes mellitus. N Engl J Med 1999;341:924–925
CrossRef Google scholar
[4]
MasudaY, MaruiS, KatoI, et al. Thermal and cardiovascular responses and thermal sensation during hot-water bathing and the influence of room temperature. J Therm Biol 2019;82:83–89
CrossRef Google scholar
[5]
YeL, WuJ, CohenP, et al. Fat cells directly sense temperature to activate thermogenesis. Proc Natl Acad Sci USA 2013;110:12480–12485
CrossRef Google scholar
[6]
PatsourisD, QiP, AbdullahiA, et al. Burn Induces Browning of the Subcutaneous White Adipose Tissue in Mice and Humans. Cell Rep 2015;13:1538–1544
CrossRef Google scholar
[7]
MaX, XuL, AlberobelloAT, et al. Celastrol Protects against Obesity and Metabolic Dysfunction through Activation of a HSF1-PGC1alpha Transcriptional Axis. Cell Metab 2015;22:695–708.
CrossRef Google scholar
[8]
YunJ, FinkelT. Mitohormesis. Cell Metab 2014;19:757–766
CrossRef Google scholar
[9]
LiY, WangD, PingX, et al. Local hyperthermia therapy induces browning of white fat and treats obesity. Cell 2022;185:949–966
CrossRef Google scholar
[10]
XuL, MaX, BagattinA, et al. The transcriptional coactivator PGC1alpha protects against hyperthermic stress via cooperation with the heat shock factor HSF1. Cell Death Dis 2016;7:e2102
CrossRef Google scholar

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2022 The Author(s) 2022. Published by Oxford University Press on behalf of Higher Education Press.
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