Linguistic profile in individuals with 22q11.2 syndrome: A systematic review

Abstract

22q11.2 syndrome is the second most common genetic condition worldwide, where communication, language, and speech are significantly affected to varying degrees. This has generated considerable interest among professionals working with this population. The objective of this research is to review studies conducted in recent years concerning language delays and difficulties experienced by individuals with 22q11.2 syndrome. A total of 21 articles were analyzed, focusing on the development of oral language, written language, and overall communication, following the PRISMA Statement guidelines and COSMIN methodology. The results highlight that individuals with 22q11.2 syndrome present significant difficulties, particularly in speech, various areas of expressive language, and in the acquisition of reading and writing skills when compared to their typically developing peers across different developmental stages. Therefore, linguistic intervention should be considered a fundamental area of support throughout the lifespan of individuals with 22q11.2 syndrome.

Keywords

22q11.2 syndrome / Language / Communication / Review

Declaration of Competing Interest

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Data availability

No data was used for the research described in the article.

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