Difference analysis of the influence of smoking on LDL, Cys-C, and hs-CRP in patients with cerebral infarction

Abstract

Objective: To compare the effects of smoking on low-density lipoprotein (LDL), cystatin C (Cys-C) and C-reactive protein (hs-CRP) in patients with cerebral infarction. Methods: The clinical data of acute stroke patients classified as large atherosclerosis by the trial of Org 10172 in acute stroke treatment (TOAST) classification were collected, and the differences of general data and results of LDL, Cys-C and hs-CRP in smoking and nonsmoking patients were compared to search for relevant clinical data with statistical significance. Results: A total of 116 patients with acute stroke classified as large atherosclerotic by TOAST were collected and divided into groups according to smoking status. Among the smoking patients, gender, age, occupation, drinking, hypertension, and diabetes were used as influencing factors to compare whether LDL was greater than or equal to 1.3 mmol/L, Cys-C≥0.8 mg/L and hs-CRP≥4 mg/L, with P values greater than 0.05. There was no statistical difference. Among non-smoking patients, occupation, alcohol consumption, and high blood pressure had statistical significance for whether LDL was greater than 1.3 mmol/L. Age, occupation, and diabetes had statistical significance for whether Cys-C was greater than 0.8 mg/L. Conclusion: In this study, there was no statistically significant impact on the test results of LDL, Cys-C, and CRP wheth- er the patients with ischemic stroke were smokers or non-smokers.

Keywords

ischemic stroke / smoke / low-density lipoprotein / cystatin C / C-reactive protein