Research progress on the biological effects of BDNF and proBDNFs in post-traumatic stress disorder

Abstract

Many people were affected psychologically and even traumatized by the outbreak of new coronavirus pneumonia in 2020, which has the potential to lead to post-traumatic stress disorder. Many neuropsychiatric illnesses are aided by brain-derived neurotrophic factor and its predecessors. Brain-derived neurotrophic factor precursors have the biological impact of triggering neuronal apoptosis and hindering neural regeneration, and brain-derived neurotrophic factor itself can help increase the growth, survival, and differentiation of central and peripheral nerve cells. This article provides an in-depth study of their biological impacts in post-traumatic stress disorder in an attempt to understand the biological effects of brain-derived neurotrophic factor and its precursor proteins.

Keywords

brain-derived neurotrophic factor / brain-derived neurotrophic factor precursors / post-traumatic stress disorder