Progress in research on the relationship between autism and folate receptor autoantibody expression

Abstract

Autism spectrum disorder (ASD) is a serious neurodevelopmental disorder, the etiology and mechanism of which are not yet clear. Studies have shown that folate deficiency can lead to abnormalities in the development of the central nervous system. Patients with autism spectrum disorders develop folate-alpha receptor autoantibodies. Folate-alpha receptor autoantibodies block folate transport, leading to a deficiency of folate in nerve tissues. Folate is effective in treating patients with folate-alpha receptor autoantibodies.

Keywords

autism spectrum disorder (ASD) / folic acid / folate alpha receptor autoantibody